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Synthesis of depsipeptides from

Hongfei CAO, Yakai FENG, Heyun WANG, Li ZHANG, Musammir KHAN, Jintang GUO

Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 4, Pages 409-415 doi: 10.1007/s11705-011-1141-9

Abstract: caprolactone-depsipeptides CL-Ala and CL-Leu were prepared by the reactions of -caprolactone (CL) with -alanine and -leucinerespectively, and -dioxanone-depsipeptide (PDO-Leu) was prepared by the reaction of -dioxanone (PDO) with -leucine

Keywords： -caprolactone p-dioxanone L-alanine L-leucine

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Insulin resistance and the metabolism of branched-chain amino acids

Jingyi Lu, Guoxiang Xie, Weiping Jia, Wei Jia

Frontiers of Medicine 2013, Volume 7, Issue 1, Pages 53-59 doi: 10.1007/s11684-013-0255-5

Abstract: Branched-chain amino acids (BCAAs), namely valine, leucine and isoleucine, are among the nine essential

Keywords： branched-chain amino acids leucine isoleucine valine insulin resistance

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Regulation of NLR stability in plant immunity

Tao WANG, Jiaxin LI, Qian-Hua SHEN

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 2, Pages 97-104 doi: 10.15302/J-FASE-2018248

Abstract:

Plant nucleotide binding domain and leucine-rich repeat (NLR) receptors recognize pathogen effectors

Keywords： E3 ubiquitin ligase degradation nucleotide-binding leucine-rich repeat receptor plant immunity proteasome

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Leucine Supplementation in a Chronically Protein-Restricted Diet Enhances Muscle Weight and Postprandial

Bo Zhang, Licui Chu, Hong Liu, Chunyuan Xie, Shiyan Qiao, Xiangfang Zeng

Engineering 2017, Volume 3, Issue 5, Pages 760-765 doi: 10.1016/J.ENG.2017.03.008

Abstract: The purpose of this study was to investigate whether leucine supplementation would increase the synthesistreatments including a 20% casein diet (CON), a 10% casein+ 0.44% alanine diet (R), and a 10% casein+ 0.87% leucineRegarding the plasma amino acid level, the RL group had the highest concentration of leucine (P<0.05In conclusion, when protein is chronically restricted in adult rat diets, leucine supplementation moderately

Keywords： Low-protein diet Leucine Growth performance Muscle weight Protein synthesis Adult rats

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Comments on the special issue on forestry of

John L. INNES

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 4, Pages 502-503 doi: 10.15302/J-FASE-2017189

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PD-1/PD-L1 blockade in cervical cancer: current studies and perspectives

Yumeng Wang, Guiling Li

Frontiers of Medicine 2019, Volume 13, Issue 4, Pages 438-450 doi: 10.1007/s11684-018-0674-4

Abstract: Checkpoint blockades targeting the PD-1/PD-L1 axis have achieved effective clinical responses with acceptableIn this review, we summarize recent advances in our understanding of the PD-1/PD-L1 signaling pathway, including the expression patterns of PD-1/PD-L1 and potential PD-1/PD-L1-related therapeutic strategies

Keywords： PD-1 PD-L1 immune checkpoint blockade antibody immunotherapy cervical cancer

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In memory of Perry L. McCarty, seminal founder of Environmental Biotechnology

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 10, doi: 10.1007/s11783-023-1730-0

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Shear design of high strength concrete prestressed girders

Emad L. LABIB,Hemant B. DHONDE,Thomas T. C. HSU,Y. L. MO

Frontiers of Structural and Civil Engineering 2014, Volume 8, Issue 4, Pages 373-387 doi: 10.1007/s11709-014-0087-7

Abstract: Normal strength prestressed concrete I-girders are commonly used as the primary superstructure components in highway bridges. However, shear design guidelines for high strength PC girders are not available in the current structural codes. Recently, ten 7.62 m (25 feet) long girders made with high strength concrete were designed, cast, and tested at the University of Houston (UH) to study the ultimate shear strength and the shear concrete contribution ( ) as a function of concrete strength ( ). A simple semi-empirical set of equations was developed based on the test results to predict the ultimate shear strength of prestressed concrete I-girders. The UH-developed set of equations is a function of concrete strength ( ), web area ( ), shear span to effective depth ratio ( / ), and percentage of transverse steel ( ). The proposed UH-Method was found to accurately predict the ultimate shear strength of PC girders with concrete strength up to 117 MPa (17000 psi) ensuring satisfactory ductility. The UH-Method was found to be not as overly conservative as the ACI-318 (2011) code provisions, and also not to overestimate the ultimate shear strength of high strength PC girders as the AASHTO LRFD (2010) code provisions. Moreover, the proposed UH-Method was found fairly accurate and not exceedingly conservative in predicting the concrete contribution to shear for concrete strength up to 117 MPa (17000 psi).

Keywords： shear design high strength concrete prestressed girders full-scale tests

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Deeply missing my career idol and role model ― Professor Perry L. McCarty

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 9, doi: 10.1007/s11783-023-1717-x

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Urban watershed management under rapid urbanization

Pengfei DU, Haifeng JIA, Shaw L. YU

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 5, Pages 595-595 doi: 10.1007/s11783-012-0452-5

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Recombinant aspartate aminotransferase-catalyzed synthesis of L-4-fluorophenylalanine

CHEN Meijuan, JIA Honghua, CHEN Yongsheng, JIANG Min, WEI Ping

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 2, Pages 220-223 doi: 10.1007/s11705-008-0041-0

Abstract: L-4-Fluorophenylalanine (FPhe) was prepared from 4-fluorophenylpyruvate (FPPA) catalyzed by aspartateconditions: 37°C, pH value range of 5.0–8.0, 5.5 mass ratio of cell to FPPA, 0.6% (w/v) of Tween 80, 7.08 g/LFPPA, and 1.6 of molar ratio of L-Asp to FPPA.

Keywords： L-4-Fluorophenylalanine Asp-AT aspartate aminotransferase 4-fluorophenylpyruvate FPPA

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Effects of different doses of cadmium on secondary metabolites and gene expression in Artemisia annua L.

Liangyun Zhou,Guang Yang,Haifeng Sun,Jinfu Tang,Jian Yang,Yizhan Wang,Thomas Avery Garran,Lanping Guo

Frontiers of Medicine 2017, Volume 11, Issue 1, Pages 137-146 doi: 10.1007/s11684-016-0486-3

Abstract: The effects of different Cd concentrations (0, 20, 60, and 120 μmol/L) on the biosynthesis of Artemisia annua L. were examined.The results showed that the application of treatment with 60 and 120 μmol/L Cd for 3 days significantlyThe concentrations of artemisinic acid, arteannuin B, and artemisinin in the 120 μmol/L Cd-treated;DBR2, ALDH1, and DXR were up-regulated in the 120 μmol/L

Keywords： Cd secondary metabolites gene expressions Artemisia annua L.

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Reactive extraction for preparation of hydrogen peroxide under pressure

CHENG Yongxi, LI Hongtao, WANG Li, LÜ Shuxiang

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 3, Pages 335-340 doi: 10.1007/s11705-008-0042-z

Abstract: The preparation of hydrogen peroxide from anthrahydroquinone by reactive extraction was investigated. The integration process of oxidation of anthrahydroquinone by air and extraction of hydrogen peroxide from the organic phase with water was carried out in a sieve plate column under pressure. The conversion of anthrahydroquinone increased with increasing pressure resulting in an increase of hydrogen peroxide concentration in the aqueous phase. However, no change in extraction efficiency of hydrogen peroxide was observed. A mathematical model for gas-liquid-liquid reactive extraction was established. In the model, the effects of pressure and gas superficial velocity on reaction were considered. With increasing gas superficial velocity, the conversion of anthrahydroquinone increased, and the fraction of hydrogen peroxide extracted reached a plateau with a maximum of 72.94%. However, both the conversion of anthrahydroquinone and the fraction of hydrogen peroxide extracted decreased with increasing organic phase superficial velocity.

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Advances in Underground Construction Help Provide Quality of Life for Modern Societies

Raymond L. Sterling

Engineering 2017, Volume 3, Issue 6, Pages 780-781 doi: 10.1016/j.eng.2017.12.006

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Size-controlled green synthesis of silver nanoparticles assisted by L-cysteine

Wenchao Zhang,Lin Zhang,Yan Sun

Frontiers of Chemical Science and Engineering 2015, Volume 9, Issue 4, Pages 494-500 doi: 10.1007/s11705-015-1527-1

Abstract: size-controlled synthesis of silver nanoparticles (Ag NPs) in aqueous solution with the assistance of L-cysteineThe size of Ag NPs decreases with the increase of L-cysteine concentration, and thus can be controlledby adjusting L-cysteine concentration.analysis shows that Ag NPs with an average size of 3 nm can be produced in the presence of 1.0 mmol/LL-cysteine, about one sixth of the size of Ag NPs obtained in the absence of L-cysteine (17 nm).

Keywords： nanoparticles silver L-cysteine size distribution synthesis