Resource Type

Journal Article 2

Year

2019 1

2014 1

Keywords

Dorper sheep 1

SCNT 1

cloned 1

cloned animal ecology 1

death 1

free-grazing synchronization 1

pig 1

placenta 1

somatic cell nuclear transfer 1

umbilical cord 1

open ︾

Search scope:

排序： Display mode:

Comparison of birth weight and umbilical and placental characteristics of cloned and artificial insemination-derived

Zheng AO, Chengfa ZHAO, Yanmin GAN, Xiao WU, Junsong SHI, Enqin ZHENG, Dewu LIU, Gengyuan CAI, Zhenfang WU, Zicong LI

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 1,   Pages 54-60 doi: 10.15302/J-FASE-2018249

Abstract:

Somatic cell nuclear transfer (SCNT)-derived piglets have significantly higher stillbirth rate and postnatal mortality rate than artificial insemination (AI)-generated piglets. The question whether the low survival rate of SCNT piglets was related to birth weight, umbilical cord or placenta development was investigated. In this study, stillbirth rate, neonatal death rate, birth weight, umbilical cord status, placental parameters and placental gene expression patterns were compared between SCNT and AI piglets. Results showed that mortality rates at birth and during the neonatal stage of SCNT piglets were significantly higher than those of AI piglets. The incidence of abnormal umbilical cord in SCNT and SCNT-liveborn (SCNT-LB) piglets was significantly higher than in AI and AI-liveborn (AI-LB) piglets. Birth weight, placental weight, placental surface area and placental efficiency in SCNT and SCNT-LB piglets were significantly lower than those of AI and AI-LB piglets. Placental expression profiles of imprinting, angiopoiesis and nutrient transport-related genes were defective in SCNT-LB piglets compared with those in AI-LB piglets. Thus, the low survival rate of SCNT piglets may be associated with abnormal umbilical cord and placenta development. These characteristics may have resulted from aberrant expression of angiogenesis, nutrient transport, and imprinting-related genes in the placentas.

Keywords： cloned     pig     death     placenta     SCNT     umbilical cord    

HTML PDF Collect

The ecological adaptability of cloned sheep to free-grazing in the Tengger Desert of Inner Mongolia,

Xinxin LI,Huijuan WANG,Guanghua SU,Zhuying WEI,Chunling BAI,Wuni-MENGHE,Yanhui HOU,Changqing YU,Shorgan BOU,Guangpeng LI

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 3,   Pages 191-200 doi: 10.15302/J-FASE-2014029

Abstract: Since the birth of the first cloned sheep, somatic cell nuclear transfer technology has been successfullyCloned livestock have no apparent health risks, and the quality and safety of the cloned animal productsare similar to non-cloned animals.The social behavior and environmental adaptability of postnatal cloned animals, especially when usedIn the present study, the cloned Dorper sheep equipped with GPS location devices were free-grazed in

Keywords： somatic cell nuclear transfer     free-grazing synchronization     Dorper sheep     cloned animal ecology    

HTML PDF Collect

Title Author Date Type Operation

Comparison of birth weight and umbilical and placental characteristics of cloned and artificial insemination-derived

Zheng AO, Chengfa ZHAO, Yanmin GAN, Xiao WU, Junsong SHI, Enqin ZHENG, Dewu LIU, Gengyuan CAI, Zhenfang WU, Zicong LI

Journal Article

The ecological adaptability of cloned sheep to free-grazing in the Tengger Desert of Inner Mongolia,

Xinxin LI,Huijuan WANG,Guanghua SU,Zhuying WEI,Chunling BAI,Wuni-MENGHE,Yanhui HOU,Changqing YU,Shorgan BOU,Guangpeng LI

Journal Article