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CD117dim/CD34+CD117bri myeloblast-associated gene expression in t(8;21

Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 608-620 doi: 10.1007/s11684-021-0836-7

Abstract: t(8;21)(q22;q22) acute myeloid leukemia (AML) is a highly heterogeneous hematological malignancy withTwo leukemic myeloblast populations (CD34 CD117 and CD34 CD117 ) were previously identified in t(8;21Here, we examined the impact of CD34 CD117 /CD34 CD117 myeloblast-associated gene expression on t(8;21In this study, 85 patients with t(8;21) AML were enrolled.CD117 myeloblast-associated gene expression may provide new clinically prognostic markers for t(8;21

Keywords： t(8     21)(q22     q22) AML     CD34+CD117dim/ CD34+CD117bri cell population    

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Development of a new method for RMR and Q classification method to optimize support system in tunneling

Asghar RAHMATI,Lohrasb FARAMARZI,Manouchehr SANEI

Frontiers of Structural and Civil Engineering 2014, Volume 8, Issue 4,   Pages 448-455 doi: 10.1007/s11709-014-0262-x

Abstract: Rock mass classification system is very suitable for various engineering design and stability analysis. classification method is confirmed by Japan Highway Public Corporation that this method can figure out either strength or deformability of rock mass, further appropriating the amount of rock bolts, thickness of shotcrete, and size of pitch of steel ribs just after the blasting procedure. Based on these advantages of method, in this study, according to data of five deep and long tunnels in Iran, two equations for estimating the value of method from and classification systems were developed. These equations as a new method were able to optimize the support system for and classification systems. From classification and its application in these case studies, it is pointed out that the method for the design of support systems in underground working is more reliable than the and classification systems.

Keywords： JH classification     Q and RMR classification     new method    

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An approach for evaluating fire resistance of high strength Q460 steel columns

Wei-Yong WANG, Guo-Qiang LI, Bao-lin YU

Frontiers of Structural and Civil Engineering 2014, Volume 8, Issue 1,   Pages 26-35 doi: 10.1007/s11709-014-0239-9

Abstract: To develop a methodology for evaluating fire resistance of high strength Q460 steel columns, the loadbearing capacity of high strength Q460 steel columns is investigated.evaluating load bearing capacity of mild steel columns at room temperature is extended to high strength Q460steel columns with due consideration to high temperature properties of high strength Q460 steel.The critical temperature of high strength Q460 steel column is presented and compared with mild steel

Keywords： high strength Q460 steel     load bearing capacity     temperature    

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Orienting the Forest Remote Sensing of the 21st Century in China

Zhao Xianwen

Strategic Study of CAE 1999, Volume 1, Issue 3,   Pages 16-21

Abstract:

In the light of the mentioned above, the forest remote sensing perspective of the 21 st century

Keywords： forestry     remote sensing     developing of sustainable forestry     forestry towards the 21 st century    

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Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology

Huating Li, Jing Zhang, Weiping Jia

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 25-30 doi: 10.1007/s11684-013-0244-8

Abstract:

Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor family.It is demonstrated that FGF21 acts on multiple tissue to coordinate carbohydrate and lipid metabolismMoreover, FGF21 also plays important roles in some physiological processes, such as fasting and feedingClinical relevance of FGF21 in humans is still unclear, and the basis and consequences of increased FGF21This article concentrates on recent advances in our understanding of FGF21.

Keywords： FGF21     metabolism     pharmacology     physiology     clinical relevance    

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Clinical characteristics and prognostic values of 1p32.3 deletion detected through fluorescence

Huanping Wang, Haitao Meng, Jinghan Wang, Yinjun Lou, Yile Zhou, Peipei Lin, Fenglin Li, Lin Liu, Huan Xu, Min Yang, Jie Jin

Frontiers of Medicine 2020, Volume 14, Issue 3,   Pages 327-334 doi: 10.1007/s11684-019-0712-x

Abstract: hybridization (FISH) was performed to detect six cytogenetic abnormalities, namely, del(1p32.3), gain(1q21), del(17p13), del(13q14), t(4;14), and t(11;14).

Keywords： 1p32.3 deletion     1q21 gain     prognosis     multiple myeloma     FISH     bortezomib     thalidomide    

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R158Q and G212S, novel pathogenic compound heterozygous variants in of Gitelman syndrome

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 932-945 doi: 10.1007/s11684-022-0963-9

Abstract: The prediction of mutant protein showed that p.R158Q and p.G212S could alter protein’s three-dimensionalMeanwhile, we conducted a compound heterozygous model—Ncc R156Q/G210S mice corresponding to human NCCR158Q/G212S.The hydrochlorothiazide test showed a loss of function of mutant Ncc in NccR156Q/G210S miceThese findings indicated that R158Q and G212S variants of SLC12A3 were pathogenic variants of

Keywords： Gitelman syndrome     mouse model     compound heterozygous     hypokalemia     Slc12a3    

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An Opinion on the Development of Oil and Gas Industry in the 21st Century

Chen Junwu

Strategic Study of CAE 2000, Volume 2, Issue 4,   Pages 21-24

Abstract:

The speed of international social-economic development closely depends upon the growth of world energy consumption, which in turn has to meet the stringent environmental protection policy that controls the total amount of greenhouse gas released to the atmosphere in the burning of fuel. In order to achieve the sustainable development of all nations, it is advisable to give an outlook to the future situation of world oil and gas industry as the representatives of the non-regenerable energy resources. This paper presents an opinion on the future development of oil and gas industry based on limited data published in literature together with controversial forecasts by different authors and covers four subjects： (1) the demand and supply of oil and gas in the new century; (2) the specifications of oil products to meet the environmental regulations; (3) the role of unconventional oil in the energy industry and (4) the brilliant future of natural gas.

Keywords： 21st centurey     petroleum     natural gas     oil and gas industry    

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Science and Technology in Human's Living and Survival in the 21st Century

Jiang Zhenghua

Strategic Study of CAE 2002, Volume 4, Issue 4,   Pages 1-11

Abstract:

This article, from the angle of management, reviews the world history over the past century, studies the prospective progress in the new century, and discusses ways for promoting world peace and cooperation and realizing common development.

Keywords： 21st century     progress in science and technology     human's living and survival    

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Simultaneous Screening of 733 Pesticide Residues in Fruits and Vegetables by a GC/LC-Q-TOFMS Combination Article

Guofang Pang, Qiaoying Chang, Ruobin Bai, Chunlin Fan, Zijuan Zhang, Hongyuan Yan, Xingqiang Wu

Engineering 2020, Volume 6, Issue 4,   Pages 432-441 doi: 10.1016/j.eng.2019.08.008

Abstract: chromatography (LC)– and gas chromatography (GC)–quadru pole-time-of-flight mass spectrometry (Q-TOFMSstandard materials as references through one sample preparation and the combination of GC/LC–Q-TOFMStechnique, the combination technique shows an improvement of 51.1% (GC–QTOFMS) and 39.6% (LC–Q-TOFMS

Keywords： Pesticide multi-residues     GC–Q-TOFMS      LC–Q-TOFMS     Accurate mass database      Spectra library      Fruits and    

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Digital manufacturing—the development direction of the manufacturing technology in the 21st century

XIONG You-lun, YIN Zhou-ping

Frontiers of Mechanical Engineering 2006, Volume 1, Issue 2,   Pages 125-130 doi: 10.1007/s11465-006-0021-3

Abstract: After introducing the concepts of digital manufacturing technology, the discipline framework of digital manufacturing is presented in the paper by discussing its basic concept, theory foundation, key technology and scientific problems in detail. As the core of the advanced manufacturing technology, digital manufacturing is gradually becoming the main manufacturing technology of the twenty-first century. Firstly, the main features of digital manufacturing are indicated and its key supporting technologies are investigated by grouping them into four levels related to product development, numerical control, production management, and enterprise collaboration, respectively. Moreover, the existing problems in the research on the multi-discipline theory foundation of digital manufacturing such as manufacturing informatics, computational manufacturing, and manufacturing intelligence, are also indicated. Then, the core scientific problems of digital manufacturing are discussed in depth, which focuses on digitization of manufacturing information, modeling of manufacturing constraints, high-speed and high-precision numerical control theory, and Internet-based collaboration and integration. Lastly, the development trends and application perspectives of digital manufacturing are concluded.

Keywords： development     foundation     multi-discipline     scientific     supporting    

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The Challenge of Computing and Information Technology in the 21st Century

Wm. A. Wulf

Strategic Study of CAE 2000, Volume 2, Issue 10,   Pages 9-12

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A New Type of Q-switched and Frequency-doubling Green Laser

Chen Fei,Huo Yujing,He Shufang,Feng Lichun

Strategic Study of CAE 2000, Volume 2, Issue 4,   Pages 39-42

Abstract:

A new type of LD pumped Nd： YV04- KTP Q-switched green laser is demonstrated.By using the KTP crystal as both an electro-optic Q-switcher and a frequency-doubling crystal in type

Keywords： KTP     green laser     electro-optic Q-switcher     frequency-doubling    

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Application research of Q&P concept in hot rolled AHSS production

Yuan Guo,Kang Jian,Zhang He,Li Yunjie,Hu Hongling and Wang Guodong

Strategic Study of CAE 2014, Volume 16, Issue 1,   Pages 59-65

Abstract: industry，the development of advanced high strength steel obtained using the quenching and partitioning （Q&In the present work，the application of Q&P concept during hot rolling was investigated for wide useof Q&P process on the conventional hot rolling production line.It was shown that introducing thermo-mechanical treatment during the conventional Q&P process wasThe feasibility of producing the hot rolled Q&P steel（DQ（direct quenching）&P steel）was determined

Keywords： advanced high strength steel     Q&P     DQ&P     hot rolling     retained austenite    

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Title Author Date Type Operation

CD117dim/CD34+CD117bri myeloblast-associated gene expression in t(8;21

Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang

Journal Article

Development of a new method for RMR and Q classification method to optimize support system in tunneling

Asghar RAHMATI,Lohrasb FARAMARZI,Manouchehr SANEI

Journal Article

An approach for evaluating fire resistance of high strength Q460 steel columns

Wei-Yong WANG, Guo-Qiang LI, Bao-lin YU

Journal Article

Orienting the Forest Remote Sensing of the 21st Century in China

Zhao Xianwen

Journal Article

Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology

Huating Li, Jing Zhang, Weiping Jia

Journal Article

Clinical characteristics and prognostic values of 1p32.3 deletion detected through fluorescence

Huanping Wang, Haitao Meng, Jinghan Wang, Yinjun Lou, Yile Zhou, Peipei Lin, Fenglin Li, Lin Liu, Huan Xu, Min Yang, Jie Jin

Journal Article

R158Q and G212S, novel pathogenic compound heterozygous variants in of Gitelman syndrome

Journal Article

An Opinion on the Development of Oil and Gas Industry in the 21st Century

Chen Junwu

Journal Article

Science and Technology in Human's Living and Survival in the 21st Century

Jiang Zhenghua

Journal Article

Simultaneous Screening of 733 Pesticide Residues in Fruits and Vegetables by a GC/LC-Q-TOFMS Combination

Guofang Pang, Qiaoying Chang, Ruobin Bai, Chunlin Fan, Zijuan Zhang, Hongyuan Yan, Xingqiang Wu

Journal Article

Digital manufacturing—the development direction of the manufacturing technology in the 21st century

XIONG You-lun, YIN Zhou-ping

Journal Article

The Challenge of Computing and Information Technology in the 21st Century

Wm. A. Wulf

Journal Article

A New Type of Q-switched and Frequency-doubling Green Laser

Chen Fei,Huo Yujing,He Shufang,Feng Lichun

Journal Article

Seminar on the Current Situation and Development Trend of New Materials in the 21st Century

Journal Article

Application research of Q&P concept in hot rolled AHSS production

Yuan Guo,Kang Jian,Zhang He,Li Yunjie,Hu Hongling and Wang Guodong

Journal Article