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FGF23 associated bone diseases

Eryuan Liao

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 65-80 doi: 10.1007/s11684-013-0254-6

Abstract:

Recently, fibroblast growth factor 23 (FGF23) has sparked widespread interest because of its potentialIn this review, we summarized the FGF superfamily, the mechanism of FGF23 on phosphate and vitamin Dmetabolism, and the FGF23 related bone disease.

Keywords： fibroblast growth factor 23     FGF receptor     phosphate metabolism     Klotho     bone disease    

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The FGF metabolic axis

Xiaokun Li

Frontiers of Medicine 2019, Volume 13, Issue 5,   Pages 511-530 doi: 10.1007/s11684-019-0711-y

Abstract: Members of the fibroblast growth factor (FGF) family play pleiotropic roles in cellular and metabolicBy contrast, FGF19, 21, and 23 coevolve through losing binding affinity for extracellular matrix heparanFGF19 metabolic axis from the ileum to liver negatively controls diurnal bile acid biosynthesis.FGF23 axes from the bone to kidney and parathyroid regulate metabolic homeostasis of phosphate, calcium, and 23 in cellular and organismal metabolism instead of cell proliferation and growth sufficiently

Keywords： FGF19     FGF21     FGF23     FGFR     metabolism     endocrine     Klotho    

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FGF13 suppresses acute myeloid leukemia by regulating bone marrow niches

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 896-908 doi: 10.1007/s11684-022-0944-z

Abstract: Fibroblast growth factor 13 (FGF13) is aberrantly expressed in multiple cancer types, suggesting itsResults showed that FGF13 was lowly expressed in patients with AML and that its elevated expression wasUnivariate and multivariate Cox regression analyses identified FGF13 as an independent prognostic factorA prognostic nomogram integrating FGF13 and clinicopathologic variables was constructed to predict 1-The xenograft study indicated that FGF13 overexpression prolonged the survival of recipient mice.

Keywords： acute myeloid leukemia     FGF13     prognosis     immune-related genes     bone marrow niches    

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Influence of retinoic acid on TBX1 expression in myocardial cells induced by Shh and Fgf8

Miao LIU, Xiaoyan WU, Jiawei XU, Runming JIN

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 61-66 doi: 10.1007/s11684-009-0007-8

Abstract: The expression of Shh and Fgf8 at mRNA and protein levels in neonatal rat myocardial cells were measuredThere was basal expression of Shh and Fgf8 in the control group.Meanwhile, we could detect that the expression of Fgf8 mRNA and protein were up-regulated by 2.50 timesThe results indicated that RA could induce the expression of Shh and Fgf8 in neonatal rat myocardialAt the same time, it has shown that Shh and Fgf8 were involved in the regulation process of RA on TBX1

Keywords： retinoic acid     Tbx1 protein     Shh protein     Fgf8 protein    

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pancreatic carcinoma by β-elemene combined with dendritic cells modified with genes encoding interleukin-23

TAN Guang, WANG Zhongyu, CHE Luanqing, YIN Shuo

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 41-45 doi: 10.1007/s11684-007-0008-4

Abstract: The dendritic cell vaccine is a treatment vaccine with potent clinical applications. Functional cytokines can enhance dendritic cell anti-tumor immune responses. This experiment was conducted to study the effects of bone marrow-deriv

Keywords： Functional     experiment     anti-tumor     dendritic     clinical    

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The important revelation of “7·23” passenger train accident

Sun Yongfu

Strategic Study of CAE 2012, Volume 14, Issue 12,   Pages 4-9

Abstract:

The process and reasons of “7·23” passenger train

Keywords： passenger train accident     the research and development management     the access management     the emergency response     the railway construction management    

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Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology

Huating Li, Jing Zhang, Weiping Jia

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 25-30 doi: 10.1007/s11684-013-0244-8

Abstract:

Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor family.It is demonstrated that FGF21 acts on multiple tissue to coordinate carbohydrate and lipid metabolismMoreover, FGF21 also plays important roles in some physiological processes, such as fasting and feedingClinical relevance of FGF21 in humans is still unclear, and the basis and consequences of increased FGF21This article concentrates on recent advances in our understanding of FGF21.

Keywords： FGF21     metabolism     pharmacology     physiology     clinical relevance    

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Artificial intelligence and wireless communications

Wang, Yi-qun Ge, Qi-fan Zhang, Wu-xian Shi,justin.wangjun@huawei.com,lirongone.li@huawei.com,wangjian23

Frontiers of Information Technology & Electronic Engineering 2020, Volume 21, Issue 10,   Pages 1413-1534 doi: 10.1631/FITEE.1900527

Abstract: The applications of (AI) and (ML) technologies in have drawn significant attention recently. AI has demonstrated real success in speech understanding, image identification, and natural language processing domains, thus exhibiting its great potential in solving problems that cannot be easily modeled. AI techniques have become an enabler in to fulfill the increasing and diverse requirements across a large range of application scenarios. In this paper, we elaborate on several typical wireless scenarios, such as channel modeling, channel decoding and signal detection, and channel coding design, in which AI plays an important role in . Then, AI and information theory are discussed from the viewpoint of the information bottleneck. Finally, we discuss some ideas about how AI techniques can be deeply integrated with wireless communication systems.
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High-quality industrial n-type silicon wafers with an efficiency of over 23% for Si heterojunction solar

Fanying MENG,Jinning LIU,Leilei SHEN,Jianhua SHI,Anjun HAN,Liping ZHANG,Yucheng LIU,Jian YU,Junkai ZHANG,Rui ZHOU,Zhengxin LIU

Frontiers in Energy 2017, Volume 11, Issue 1,   Pages 78-84 doi: 10.1007/s11708-016-0435-5

Abstract: Fortunately, over 23% of the conversion efficiency of the SHJ solar cell with a wafer thickness of 100

Keywords： n-type Cz-Si     thinner wafer     surface texture     high efficiency     SHJ solar cell    

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Research and Development of Heat-Resistant Materials for Advanced USC Power Plants with Steam Temperatures of 700 °C and Above Review

Fujio Abe

Engineering 2015, Volume 1, Issue 2,   Pages 211-224 doi: 10.15302/J-ENG-2015031

Abstract:

Materials-development projects for advanced ultra-supercritical (A-USC) power plants with steam temperatures of 700 °C and above have been performed in order to achieve high efficiency and low CO2 emissions in Europe, the US, Japan, and recently in China and India as well. These projects involve the replacement of martensitic 9%−12% Cr steels with nickel (Ni)-base alloys for the highest temperature boiler and turbine components in order to provide sufficient creep strength at 700 °C and above. To minimize the require­ment for expensive Ni-base alloys, martensitic 9%−12% Cr steels can be applied to the next highest temperature components of an A-USC power plant, up to a maximum of 650 °C. This paper comprehensively describes the research and development of Ni-base alloys and martensitic 9%−12% Cr steels for thick section boiler and turbine components of A-USC power plants, mainly focusing on the long-term creep-rupture strength of base metal and welded joints, strength loss in welded joints, creep-fatigue properties, and microstructure evolution during exposure at elevated temperatures.

Keywords： strength     creep-fatigue property     welded joint     grain boundary     microstructure     &gamma     &prime     M23    

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Evidence for lung repair and regeneration in humans: key stem cells and therapeutic functions of fibroblast growth factors

Xuran Chu, Chengshui Chen, Chaolei Chen, Jin-San Zhang, Saverio Bellusci, Xiaokun Li

Frontiers of Medicine 2020, Volume 14, Issue 3,   Pages 262-272 doi: 10.1007/s11684-019-0717-5

Abstract: basal cells, broncho-alveolar stem cells, and alveolar type 2 cells, rely on fibroblast growth factor (FGFrecent clinical trial for acute respiratory distress syndrome (ARDS) using intravenous injection of FGF7

Keywords： FGF     human lung     repair     regeneration     stem cells    

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Title Author Date Type Operation

FGF23 associated bone diseases

Eryuan Liao

Journal Article

The FGF metabolic axis

Xiaokun Li

Journal Article

FGF13 suppresses acute myeloid leukemia by regulating bone marrow niches

Journal Article

Influence of retinoic acid on TBX1 expression in myocardial cells induced by Shh and Fgf8

Miao LIU, Xiaoyan WU, Jiawei XU, Runming JIN

Journal Article

pancreatic carcinoma by β-elemene combined with dendritic cells modified with genes encoding interleukin-23

TAN Guang, WANG Zhongyu, CHE Luanqing, YIN Shuo

Journal Article

The important revelation of “7·23” passenger train accident

Sun Yongfu

Journal Article

Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology

Huating Li, Jing Zhang, Weiping Jia

Journal Article

Artificial intelligence and wireless communications

Wang, Yi-qun Ge, Qi-fan Zhang, Wu-xian Shi,justin.wangjun@huawei.com,lirongone.li@huawei.com,wangjian23

Journal Article

High-quality industrial n-type silicon wafers with an efficiency of over 23% for Si heterojunction solar

Fanying MENG,Jinning LIU,Leilei SHEN,Jianhua SHI,Anjun HAN,Liping ZHANG,Yucheng LIU,Jian YU,Junkai ZHANG,Rui ZHOU,Zhengxin LIU

Journal Article

Research and Development of Heat-Resistant Materials for Advanced USC Power Plants with Steam Temperatures of 700 °C and Above

Fujio Abe

Journal Article

Evidence for lung repair and regeneration in humans: key stem cells and therapeutic functions of fibroblast growth factors

Xuran Chu, Chengshui Chen, Chaolei Chen, Jin-San Zhang, Saverio Bellusci, Xiaokun Li

Journal Article