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Advances on the application of ocean color remote sensing engineering in China

Pan Delu,Bai Yan

Strategic Study of CAE 2008, Volume 10, Issue 9,   Pages 14-24

Abstract: In this paper, firstly, four major technical advances are describing, including 1) the radiative transfertakes effect on marine environment monitoring, with four major kinds of application systems, namely, 1)With Chinese second ocean color satellite (HY-1B) orbiting on April 11, 2007 and the development of airborne

Keywords： ocean color remote sensing     operational application system     Chinese ocean color satellite series     HY-1A/Bocean color remote sensing     operational application system     Chinese ocean color satellite series     HY-1A    

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Ultraviolet-B induced expression of hypoxia-inducible factor 1α, transferrin receptor through EGFR/PI3K/AKT/DEC1 pathway

LI Yanhua, BI Zhigang

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 79-86 doi: 10.1007/s11684-007-0016-4

Abstract: The aim of this research was to explore the effects and signaling pathway of ultraviolet-B (UVB) irradiationon the expression of hypoxia-inducible factor 1α (HIF-1α) and transferrin receptor (TfR).The DEC1 (-/-) Ha-Cat cells did not increase their TfR and HIF-1α expressions following UVB irradiationIn contrast, DEC1 (+/+) HaCat cells strongly enhanced TfR and HIF-1?We conclude that UVB induces TfR and HIF-1αexpressions via EGFR/PI3K/AKT/DEC1 signaling pathway.
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Superenhancers activate the autophagy-related genes Beclin1 and LC3B to drive metastasis and drug resistance

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 883-895 doi: 10.1007/s11684-022-0919-0

Abstract: We further examined the expression of the autophagy-related genes Beclin1 and LC3B in 82 patients throughimmunohistochemistry and found that Beclin1 and LC3B were highly related to unfavorable prognosis ofKnockdown of Beclin1 and LC3B reduced invasion, metastasis, and proliferation in metastatic osteosarcomademonstrated that autophagy-related genes were activated by SEs and that the inhibition of SEs by JQ-1

Keywords： osteosarcoma     autophagy     metastasis     drug resistance     Beclin1     LC3B    

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An Eight-Step Continuous-Flow Total Synthesis of Vitamin B1 Article

Meifen Jiang, Minjie Liu, Weijian Li, Yingqi Xia, Fener Chen

Engineering 2024, Volume 32, Issue 1,   Pages 230-239 doi: 10.1016/j.eng.2023.01.016

Abstract:

Vitamin B1 is widely applied in the healthcare and food industry as an antineuritic andThis study reports on an integrated eight-step continuous-flow synthesis of vitamin B1 fromVitamin B1 was produced with a separated yield of 47.7% and high purity, with a total residence

Keywords： Vitamin B1     Continuous-flow synthesis     Micro-reactor     Continuous manufacturing    

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HY-2A radar altimeter design and in flight results

Xu Ke,Liu Heguang,Jiang Jingshan

Strategic Study of CAE 2013, Volume 15, Issue 7,   Pages 25-32

Abstract:

HY-2A is the first satellite for oceanic dynamic environment measurementAs one of main payloads of HY-2A, HY-2A radar altimeter has obtained successive measurement data afterThe accuracy of HY-2A radar altimeter is better than 4 cm (at 20 m significant wave height) or 2 cm (In this paper, the design and in flight preliminary results of HY-2A radar altimeter are introduced.

Keywords： radar altimeter     HY-2A satellite     operation in flight    

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Gene therapy for hemophilia B mice with scAAV8-LP1-hFIX

Wei Lu,Qingzhang Zhou,Hao Yang,Hao Wang,Yexing Gu,Qi Shen,Jinglun Xue,Xiaoyan Dong,Jinzhong Chen

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 212-218 doi: 10.1007/s11684-016-0438-y

Abstract:

Hemophilia B is a hemorrhagic disease caused by the deficiency of clotting factor IX (FIX).However, two main problems that should be solved in gene therapy for hemophilia B are immunity and safetyimmunogenicity and high transfection efficiency in liver cells, might be a potential vector for hemophilia BA strong liver-specific promoter-1 (LP1) was inserted and mutant human FIX Arg338Ala was introduced intoOur study provides a potential gene therapy method for hemophilia B.

Keywords： hemophilia B     AAV8     hFIX     gene therapy    

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The study on oceanic vector wind field retrieve technique of the HY-2 satellite

Jiang Xingwei,Lin Mingsen

Strategic Study of CAE 2009, Volume 11, Issue 10,   Pages 86-95

Abstract: retrieving oceanic vector wind algorithm and the precision analysis of its error in accordance with the HYprocess of data acquisition, pre-process, wind vector retrieve and production manufacture about the HYIt will be ready on technology for making a due ontribution once the HY-2 satellite is launched and promotes

Keywords： HY-2 satellite     microwave scatterometer     wind firld retrieve     vector wind filed error analysis    

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Association of miRNA-122-binding site polymorphism at the interleukin-1 α gene and its interaction withhepatitis B virus mutations with hepatocellular carcinoma risk

Du Yan, Han Xue, Pu Rui, Xie Jiaxin, Zhang Yuwei, Cao Guangwen

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 217-226 doi: 10.1007/s11684-014-0326-2

Abstract: designed to investigate the contribution of miRNA-122-binding site polymorphism at the IL-1A gene and its multiplicative interactions with hepatitis B virus (HBV) mutations in the risk

Keywords： hepatocellular carcinoma (HCC)     interaction     miRNA-122-binding site     IL-1A     rs3783553     hepatitis B virus (    

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Netrin-1 works with UNC5B to regulate angiogenesis in diabetic kidney disease

Xiaojing Jiao, Dong Zhang, Quan Hong, Lei Yan, Qiuxia Han, Fengmin Shao, Guangyan Cai, Xiangmei Chen, Hanyu Zhu

Frontiers of Medicine 2020, Volume 14, Issue 3,   Pages 293-304 doi: 10.1007/s11684-019-0715-7

Abstract: Netrin-1, an axon guidance factor, and its receptor UNC5B play important roles in axonal developmentNetrin-1 and UNC5B were upregulated in streptozotocin-induced DKD Wistar rats, and their expression wasNetrin-1 treatment also eliminated the pro-angiogenic effects of exogenous VEGF-165 on UNC5B-silencedThese results indicate that UNC5B antagonizes netrin-1 and that UNC5B upregulation contributes partlyTherefore, introducing exogenous netrin-1 and depleting endogenous UNC5B are potential strategies for

Keywords： netrin-1     VEGF-165     UNC5B     angiogenesis     diabetic kidney disease    

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Loss of liver kinase B1 causes planar polarity defects in cochlear hair cells in mice

Yuqin Men,Aizhen Zhang,Liwen Zhang,Yecheng Jin,Zhishuo Wang,Jing Zhao,Xiaolin Yu,Jian Zhang,Jiangang Gao

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 481-489 doi: 10.1007/s11684-016-0494-3

Abstract:

The tumor suppressor gene liver kinase B1 (LKB1), also called STK11, encodes a serine/threonine kinaseLKB1 plays crucial roles in cell differentiation, proliferation, and polarity.In this study, LKB1 conditional knockout mice (LKB1Pax2 CKO mice) were generated usingLKB1Pax2 CKO mice died perinatally.LKB1 deficiency in LKB1Pax2 CKO mice thus disrupted hair cell planar polarity during

Keywords： LKB1     stereociliary bundles     kinocilium     planar cell polarity     hearing     mice    

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Molecular characterization of two suppressor of cytokine signaling 1 genes (

Xue XU,Jiannan ZHANG,Juan LI,Yajun WANG

Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 1,   Pages 73-83 doi: 10.15302/J-FASE-2015044

Abstract: Suppressor of cytokine signaling 1 (SOCS1) protein can inhibit the signal transduction triggered by someamino acid protein, which shares high amino acid sequence identity (64%–67%) with human and mouse SOCS1.and cSOCS1a.and SOCS1b proteins can negatively regulate GH/PRL signaling.Taken together, these data suggest that both cSOCS1a and cSOCS1b may function as negative regulators

Keywords： chicken     SOCS1a     SOCS1b     growth hormone     prolactin    

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Three-dimensional face point cloud hole-filling algorithm based on binocular stereo matching and a B-spline Research Articles

Yuan HUANG, Feipeng DA,whhbb@163.com

Frontiers of Information Technology & Electronic Engineering 2022, Volume 23, Issue 3,   Pages 398-408 doi: 10.1631/FITEE.2000508

Abstract: When obtaining three-dimensional (3D) face point cloud data based on structured light, factors related to the environment, occlusion, and illumination intensity lead to holes in the collected data, which affect subsequent recognition. In this study, we propose a hole-filling method based on stereo-matching technology combined with a . The algorithm uses phase information acquired during raster projection to locate holes in the point cloud, simultaneously extracting boundary point cloud sets. By registering the face point cloud data using the stereo-matching algorithm and the data collected using the raster projection method, some supplementary information points can be obtained at the holes. The shape of the curve can then be roughly described by a few key points, and the control points are put into the hole area as key points for iterative calculation of surface reconstruction. Simulations using smooth ceramic cups and human face models showed that our model can accurately reproduce details and accurately restore complex shapes on the test surfaces. Simulation results indicated the robustness of the method, which is able to fill holes on complex areas such as the inner side of the nose without a prior model. This approach also effectively supplements the hole information, and the patched point cloud is closer to the original data. This method could be used across a wide range of applications requiring accurate facial recognition.

Keywords： Three-dimensional (3D) point cloud     Hole filling     Stereo matching     B-spline    

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Irreversible phenotypic perturbation and functional impairment of B cells during HIV-1 infection

Jingjing Yan, Shuye Zhang, Jun Sun, Jianqing Xu, Xiaoyan Zhang

Frontiers of Medicine 2019, Volume 13, Issue 3,   Pages 409-409 doi: 10.1007/s11684-018-0618-z

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Geolocation method of HY-2 satellite microwave radiometer

Wu Kuiqiao,Lin Mingsen,Guo Zhenyu

Strategic Study of CAE 2014, Volume 16, Issue 6,   Pages 21-26

Abstract:

Using cone scanning method, microwave radiometer of HY-2 satellite measuresThis article represents one geolocation method applied to the microwave radiometer of HY-2 satellite

Keywords： HY-2 satellite     geolocation     coordinate system    

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Verification of HY-2 satellite radar altimeter wind retrieval

Jia Yongjun,Zhang Youguang,Lin Mingsen

Strategic Study of CAE 2014, Volume 16, Issue 6,   Pages 54-59

Abstract: The HY-2 satellite altimeter provides sea surface height, significant wave height, sea surface wind speedIn this study, the two-parameter algorithm is used to get the wind speed from HY-2 satellite radar altimeterThe correctness of this algorithm is calculated using the Jason-1 and HY-2 scatterometer data qualitatively

Keywords： wind speed retrieval     two-parameter algorithm     radar altimeter     HY-2    

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Title Author Date Type Operation

Advances on the application of ocean color remote sensing engineering in China

Pan Delu,Bai Yan

Journal Article

Ultraviolet-B induced expression of hypoxia-inducible factor 1α, transferrin receptor through EGFR/PI3K/AKT/DEC1 pathway

LI Yanhua, BI Zhigang

Journal Article

Superenhancers activate the autophagy-related genes Beclin1 and LC3B to drive metastasis and drug resistance

Journal Article

An Eight-Step Continuous-Flow Total Synthesis of Vitamin B1

Meifen Jiang, Minjie Liu, Weijian Li, Yingqi Xia, Fener Chen

Journal Article

HY-2A radar altimeter design and in flight results

Xu Ke,Liu Heguang,Jiang Jingshan

Journal Article

Gene therapy for hemophilia B mice with scAAV8-LP1-hFIX

Wei Lu,Qingzhang Zhou,Hao Yang,Hao Wang,Yexing Gu,Qi Shen,Jinglun Xue,Xiaoyan Dong,Jinzhong Chen

Journal Article

The study on oceanic vector wind field retrieve technique of the HY-2 satellite

Jiang Xingwei,Lin Mingsen

Journal Article

Association of miRNA-122-binding site polymorphism at the interleukin-1 α gene and its interaction withhepatitis B virus mutations with hepatocellular carcinoma risk

Du Yan, Han Xue, Pu Rui, Xie Jiaxin, Zhang Yuwei, Cao Guangwen

Journal Article

Netrin-1 works with UNC5B to regulate angiogenesis in diabetic kidney disease

Xiaojing Jiao, Dong Zhang, Quan Hong, Lei Yan, Qiuxia Han, Fengmin Shao, Guangyan Cai, Xiangmei Chen, Hanyu Zhu

Journal Article

Loss of liver kinase B1 causes planar polarity defects in cochlear hair cells in mice

Yuqin Men,Aizhen Zhang,Liwen Zhang,Yecheng Jin,Zhishuo Wang,Jing Zhao,Xiaolin Yu,Jian Zhang,Jiangang Gao

Journal Article

Molecular characterization of two suppressor of cytokine signaling 1 genes (

Xue XU,Jiannan ZHANG,Juan LI,Yajun WANG

Journal Article

Three-dimensional face point cloud hole-filling algorithm based on binocular stereo matching and a B-spline

Yuan HUANG, Feipeng DA,whhbb@163.com

Journal Article

Irreversible phenotypic perturbation and functional impairment of B cells during HIV-1 infection

Jingjing Yan, Shuye Zhang, Jun Sun, Jianqing Xu, Xiaoyan Zhang

Journal Article

Geolocation method of HY-2 satellite microwave radiometer

Wu Kuiqiao,Lin Mingsen,Guo Zhenyu

Journal Article

Verification of HY-2 satellite radar altimeter wind retrieval

Jia Yongjun,Zhang Youguang,Lin Mingsen

Journal Article