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Hybrid polymer biomaterials for bone tissue regeneration

Bo Lei, Baolin Guo, Kunal J. Rambhia, Peter X. Ma

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 189-201 doi: 10.1007/s11684-018-0664-6

Abstract: Therefore, there is an increasing interest in developing degradable hybrid polymer biomaterials withIn this review, we highlight the design and synthesis of degradable hybrid polymer biomaterials and focus

Keywords： hybrid polymer     bone regeneration     tissue engineering     biomaterials    

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Minimally Invasive Implantable Biomaterials for Bone Reconstruction

Feng Han,Zhao Liu,Qiang Wei,Luguang Ding,Li Yu,Jiayuan Wang,Huan Wang,Weidong Zhang,Yingkang Yu,Yantao Zhao,Song Chen,Bin Li,

Engineering doi: 10.1016/j.eng.2024.01.031

Abstract: The application of biomaterials has become an inextricable part of treatment for new bone formation andDifferent from traditional bone-regeneration materials, injectable biomaterials-ranging from bioceramicsIn this review, we summarize the most recent developments in minimally invasive implantable biomaterialsfor bone reconstruction and different ways to achieve osteogenesis, with a focus on injectable biomaterialsRecent progress in injectable biomaterials with multiple functionalities and bioresponsive properties

Keywords： Bone     Regeneration     Implantable biomaterials     Biomedical applications     Minimal intervention    

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Biomimetic Design of Biomaterials

Yao Kangde,Shen Feng

Strategic Study of CAE 2000, Volume 2, Issue 6,   Pages 16-20

Abstract:

The research on biomaterials has gotten achievements during the past 30 years.It prompts people to design biomaterials through biomimetic approaches.of artificial extracellular matrixes and the control of apoptosis based on the interaction between biomaterialsIn view of the broadness and flexibility life science, it is recommended to design the biomaterials onof intelligent and environment-friendshiply biomaterials.

Keywords： biomaterials     biomimetic     artificial ECMs    

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Anti RNA Viruses Related Biomaterials

Yao Kangde,Yin Yuji,Zhang Baolian,Zhao Liguo

Strategic Study of CAE 2003, Volume 5, Issue 7,   Pages 17-23

Abstract: Nowadays biomaterials matrixes or vectors are developing toward the third generation, i.e. cell or/andIt is sure that biomaterials will play a crucial role in fighting against SARS viruses and the like.

Keywords： Anti-RNA viruses     protein     DNA     polysaccharide     biomaterials    

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Recent Progress in Biomaterials-Tissue Engineering

Xiaosong Gu

Engineering 2022, Volume 13, Issue 6,   Pages 1-1 doi: 10.1016/j.eng.2022.04.005

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Surface modification of biomaterials by photochemical immobilization and photograft polymerization to

Yakai FENG, Haiyang ZHAO, Li ZHANG, Jintang GUO,

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 3,   Pages 372-381 doi: 10.1007/s11705-010-0005-z

Abstract: Recent progresses and strategies to improve the hemocompatibility of biomaterials by surface modificationThis surface modification is a promising strategy for biomaterials especially for cardiovascular grafts

Keywords： biomimetic amphiphilic     amphiphilic phosphorylcholine     endothelial     functional     biomaterial    

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Regenerative Engineering for Knee Osteoarthritis Treatment: Biomaterials and Cell-Based Technologies

Jorge L. Escobar Ivirico, Maumita Bhattacharjee, Emmanuel Kuyinu, Lakshmi S. Nair, Cato T. Laurencin

Engineering 2017, Volume 3, Issue 1,   Pages 16-27 doi: 10.1016/J.ENG.2017.01.003

Abstract: The use of advanced biomaterials and stem cells independently or in conjunction to treat knee OA could

Keywords： Knee osteoarthritis     Osteoarthritic pain     Mesenchymal stem cells     Biomaterials     Regenerative engineering    

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Biocompatibility Pathways in Tissue-Engineering Templates Perspective

David F. Williams

Engineering 2018, Volume 4, Issue 2,   Pages 286-290 doi: 10.1016/j.eng.2018.03.007

Abstract: through a systematic combination of molecular and mechanical signals, usually involves the assistance of biomaterials-based

Keywords： Biomaterials     Scaffolds     Mechanotransduction     Inflammation     Topography    

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Application of Biomaterials in Cardiac Repair and Regeneration Review

Zhi Cui,Baofeng Yang,Ren-Ke Li

Engineering 2016, Volume 2, Issue 1,   Pages 141-148 doi: 10.1016/J.ENG.2016.01.028

Abstract: Biomaterials, both natural and synthetic, exhibit great potential in cardiac repair and regeneration,, we discuss the current treatment options for several cardiovascular diseases, as well as types of biomaterials

Keywords： Myocardial infarction     Heart regeneration     Biomaterial     Tissue engineering     Stem cell    

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3D Photo-Fabrication for Tissue Engineering and Drug Delivery Review

Rúben F. Pereira, Paulo J. Bártolo

Engineering 2015, Volume 1, Issue 1,   Pages 90-112 doi: 10.15302/J-ENG-2015015

Abstract:

The most promising strategies in tissue engineering involve the integration of a triad of biomaterials

Keywords： 3D photo-fabrication     biomaterials     tissue engineering     drug delivery    

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Microfluidic Generation of Multicomponent Soft Biomaterials Review

Yuetong Wang, Luoran Shang, Yuanjin Zhao, Lingyun Sun

Engineering 2022, Volume 13, Issue 6,   Pages 128-143 doi: 10.1016/j.eng.2021.02.026

Abstract:

Soft biomaterials hold great potential for a plethora of biomedical applications because of theirMulticomponent soft biomaterials are particularly attractive as a way of accommodating components maderecent decades, much progress has been achieved in the microfluidic fabrication of multicomponent soft biomaterialsIn the paper, we summarize current progress in multicomponent soft biomaterials derived from microfluidics

Keywords： Soft biomaterial     Microfluidics     Multicomponent     Microparticle     Microfiber    

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3D Printing Strategies for Precise and Functional Assembly of Silk-based Biomaterials

Xiaoliang Cui, Jun Zhang, Yan Qian, Siqi Chang, Benjamin James Allardyce, Rangam Rajkhowa, Hui Wang, Ke-Qin Zhang

Engineering 2024, Volume 34, Issue 3,   Pages 92-108 doi: 10.1016/j.eng.2023.09.022

Abstract:

In recent years, significant progress has been made in both three-dimensional (3D) printing technologies and the exploration of silk as an ink to produce biocompatible constructs. Combined with the unlimited design potential of 3D printing, silk can be processed into a broad range of functional materials and devices for various biomedical applications. The ability of silk to be processed into various materials, including solutions, hydrogels, particles, microspheres, and fibers, makes it an excellent candidate for adaptation to different 3D printing techniques. This review presents a didactic overview of the 3D printing of silk-based materials, major categories of printing techniques, and their prototyping mechanisms and structural features. In addition, we provide a roadmap for researchers aiming to incorporate silk printing into their own work by summarizing promising strategies from both technical and material aspects, to relate state-of-the-art silk-based material processing with fast-developing 3D printing technologies. Thus, our focus is on elucidating the techniques and strategies that advance the development of precise assembly strategies for silk-based materials. Precise printing (including high printing resolution, complex structure realization, and printing fidelity) is a prerequisite for the digital design capability of 3D printing technology and would definitely broaden the application era of silk, such as complex biomimetic tissue structures, vasculatures, and transdermal microneedles.

Keywords： 3D printing     Bioink     Bioprinting     Silk fibroin    

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Mechanically Strong Proteinaceous Fibers: Engineered Fabrication by Microfluidics Review

Jing Sun, Jingsi Chen, Kai Liu, Hongbo Zeng

Engineering 2021, Volume 7, Issue 5,   Pages 615-623 doi: 10.1016/j.eng.2021.02.005

Abstract:

Lightweight and mechanically strong natural silk fibers have been extensively investigated over the past decades. Inspired by this research, many artificial spinning techniques (wet spinning, dry spinning, electrospinning, etc.) have been developed to fabricate robust protein fibers. As the traditional spinning methods provide poor control over the as-spun fibers, microfluidics has been integrated with these techniques to allow the fabrication of biological fibers in a well-designed manner, with simplicity and cost efficiency. The mechanical behavior of the developed fibers can be precisely modulated by controlling the type and size of microfluidic channel, flow rate, and shear force. This technique has been successfully used to manufacture a broad range of protein fibers, and can accelerate the production and application of protein fibers in various fields. This review outlines recent progress in the design and fabrication of protein-based fibers based on microfluidics. We first briefly discuss the natural spider silk-spinning process and the microfluidics spinning process. Next, the fabrication and mechanical properties of regenerated protein fibers via microfluidics are discussed, followed by a discussion of recombinant protein fibers. Other sourced protein fibers are also reviewed in detail. Finally, a brief outlook on the development of microfluidic technology for producing protein fibers is presented.

Keywords： Proteinaceous fibers     Microfluidics     Soft materia     l Biomaterials    

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Modification of polycarbonateurethane surface with poly(ethylene glycol) monoacrylate and phosphorylcholine glyceraldehyde for anti-platelet adhesion

Jing YANG,Juan LV,Bin GAO,Li ZHANG,Dazhi YANG,Changcan SHI,Jintang GUO,Wenzhong LI,Yakai FENG

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 2,   Pages 188-196 doi: 10.1007/s11705-014-1414-1

Abstract: method using both PEG and phosphorylcholine may be applied in surface modification of blood-contacting biomaterials

Keywords： glycol) monoacrylate     phosphorylcholine     polycarbonateurethane     surface modification     anti-platelet adhesion     biomaterials    

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Biomaterial-Related Cell Microenvironment in Tissue Engineering and Regenerative Medicine Review

Jingming Gao, Xiaoye Yu, Xinlei Wang, Yingning He, Jiandong Ding

Engineering 2022, Volume 13, Issue 6,   Pages 31-45 doi: 10.1016/j.eng.2021.11.025

Abstract: influence the cell microenvironment is a fundamental research topic in the fields of cell biology, biomaterialsits surrounding cells and soluble factors, but also its extracellular matrix (ECM) or nearby external biomaterials

Keywords： Tissue engineering     Regenerative medicine     Biomaterials     Cell microenvironment     Porous scaffold     Surface    

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Title Author Date Type Operation

Hybrid polymer biomaterials for bone tissue regeneration

Bo Lei, Baolin Guo, Kunal J. Rambhia, Peter X. Ma

Journal Article

Minimally Invasive Implantable Biomaterials for Bone Reconstruction

Feng Han,Zhao Liu,Qiang Wei,Luguang Ding,Li Yu,Jiayuan Wang,Huan Wang,Weidong Zhang,Yingkang Yu,Yantao Zhao,Song Chen,Bin Li,

Journal Article

Biomimetic Design of Biomaterials

Yao Kangde,Shen Feng

Journal Article

Anti RNA Viruses Related Biomaterials

Yao Kangde,Yin Yuji,Zhang Baolian,Zhao Liguo

Journal Article

Recent Progress in Biomaterials-Tissue Engineering

Xiaosong Gu

Journal Article

Surface modification of biomaterials by photochemical immobilization and photograft polymerization to

Yakai FENG, Haiyang ZHAO, Li ZHANG, Jintang GUO,

Journal Article

Regenerative Engineering for Knee Osteoarthritis Treatment: Biomaterials and Cell-Based Technologies

Jorge L. Escobar Ivirico, Maumita Bhattacharjee, Emmanuel Kuyinu, Lakshmi S. Nair, Cato T. Laurencin

Journal Article

Biocompatibility Pathways in Tissue-Engineering Templates

David F. Williams

Journal Article

Application of Biomaterials in Cardiac Repair and Regeneration

Zhi Cui,Baofeng Yang,Ren-Ke Li

Journal Article

3D Photo-Fabrication for Tissue Engineering and Drug Delivery

Rúben F. Pereira, Paulo J. Bártolo

Journal Article

Microfluidic Generation of Multicomponent Soft Biomaterials

Yuetong Wang, Luoran Shang, Yuanjin Zhao, Lingyun Sun

Journal Article

3D Printing Strategies for Precise and Functional Assembly of Silk-based Biomaterials

Xiaoliang Cui, Jun Zhang, Yan Qian, Siqi Chang, Benjamin James Allardyce, Rangam Rajkhowa, Hui Wang, Ke-Qin Zhang

Journal Article

Mechanically Strong Proteinaceous Fibers: Engineered Fabrication by Microfluidics

Jing Sun, Jingsi Chen, Kai Liu, Hongbo Zeng

Journal Article

Modification of polycarbonateurethane surface with poly(ethylene glycol) monoacrylate and phosphorylcholine glyceraldehyde for anti-platelet adhesion

Jing YANG,Juan LV,Bin GAO,Li ZHANG,Dazhi YANG,Changcan SHI,Jintang GUO,Wenzhong LI,Yakai FENG

Journal Article

Biomaterial-Related Cell Microenvironment in Tissue Engineering and Regenerative Medicine

Jingming Gao, Xiaoye Yu, Xinlei Wang, Yingning He, Jiandong Ding

Journal Article