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演化算法 1

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Local resistance of fluid flow across sudden contraction in small channels

Hang GUO, Ling WANG, Jian YU, Fang YE, Chongfang MA, Zhuo LI,

《能源前沿（英文）》 2010年第4卷第2期页码 149-154 doi: 10.1007/s11708-009-0060-7

摘要： The pressure drop caused by flow area contraction in microchannels has been experimentally studied in this paper using the tiny gap pressure measurement method. The working fluid was deionized water at room temperature at near-atmospheric pressure. Three test sections with area ratios of 0.284 and 0.274 and at different tube diameter sizes were used. The experimental results show that the abrupt contraction coefficient decreases with the Reynolds number increasing, and it is much higher than that of conventional tubes in laminar flow. The widely-applied correlation =0.5(1−) could not predict the contraction coefficient of turbulent flow in the micro tubes. The decreases as the tube diameter increases. The transition from laminar to turbulent flow is not obvious when the diameter of the small tube is 0.32mm.

关键词： microchannels pressure drop abrupt contraction loss coefficients

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Assessment of novel nature-inspired fuzzy models for predicting long contraction scouring and related

《结构与土木工程前沿（英文）》 2021年第15卷第3期页码 665-681 doi: 10.1007/s11709-021-0713-0

摘要： The scouring phenomenon is one of the major problems experienced in hydraulic engineering. In this study, an adaptive neuro-fuzzy inference system is hybridized with several evolutionary approaches, including the ant colony optimization, genetic algorithm, teaching-learning-based optimization, biogeographical-based optimization, and invasive weed optimization for estimating the long contraction scour depth. The proposed hybrid models are built using non-dimensional information collected from previous studies. The proposed hybrid intelligent models are evaluated using several statistical performance metrics and graphical presentations. Besides, the uncertainty of models, variables, and data are inspected. Based on the achieved modeling results, adaptive neuro-fuzzy inference system–biogeographic based optimization (ANFIS-BBO) provides superior prediction accuracy compared to others, with a maximum correlation coefficient (R_test = 0.923) and minimum root mean square error value (RMSE_test = 0.0193). Thus, the proposed ANFIS-BBO is a capable cost-effective method for predicting long contraction scouring, thus, contributing to the base knowledge of hydraulic structure sustainability.

关键词： long contraction scour prediction uncertainty ANFIS model meta-heuristic algorithm

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基于空间收缩的并行演化算法

王涛,李歧强

《中国工程科学》 2003年第5卷第3期页码 57-61

摘要：

提出了一种基于空间收缩的求解MINLP问题的新算法。算法应用了快速有效的不完全演化搜索较优解的分布信息，通过分布信息定位最优解的可能分布，再由精英个体信息决定下次搜索空间。仿真结果表明该算法在搜索效率、应用范围、解的精确性和鲁棒性上都优于其他现存演化算法。

关键词：空间收缩演化算法 MINLP

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Crk-associated substrate, vascular smooth muscle and hypertension

TANG Dale

《医学前沿（英文）》 2008年第2卷第4期页码 323-331 doi: 10.1007/s11684-008-0062-6

摘要： Hypertension is characterized by vascular smooth muscle constriction and vascular remodeling involving cell migration, hypertrophy and growth. Crk-associated substrate (CAS), the first discovered member of the adapter protein CAS family, has been shown to be a critical cellular component that regulates various smooth muscle functions. In this review, the molecular structure and protein interactions of the CAS family members are summarized. Evidence for the role of CAS in the regulation of vascular smooth muscle contractility is presented. Contraction stimulation induces CAS phosphorylation on Tyr-410 in arterial smooth muscle, creating the binding site for the Src homology (SH) 2/SH3 protein CrkII, which activates neuronal Wiskott-Aldrich syndrome protein (N-WASP)-mediated actin assembly and force development. The functions of CAS in cell migration, hypertrophy and growth are also summarized. Abelson tyrosine kinase (Abl), c-Src, focal adhesion kinase (FAK), proline-rich tyrosine kinase 2 (PYK2), protein tyrosine phosphatase-proline, glutamate, serine and threonine sequence protein (PTP-PEST) and SHP-2 have been documented to coordinate the phosphorylation and dephosphorylation of CAS. The downstream signaling partners of CAS in the context of cell motility, hypertrophy, survival and growth are also discussed. These new findings establish the important role of CAS in the modulation of vascular smooth muscle functions. Furthermore, the upstream regulators of CAS may be new biologic targets for the development of more effective and specific treatment of cardiovascular diseases such as hypertension.

关键词： Contraction stimulation phosphatase-proline molecular structure discovered hypertension