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Expression and clinical implication of PRL-1 and PRL-3 in transitional cell carcinoma of bladder

Bin HAO, Changwei LIU, Huixiang LI

《医学前沿（英文）》 2009年第3卷第2期页码 197-203 doi: 10.1007/s11684-009-0036-3

摘要： The mRNA and protein expression of phosphatase of regenerating liver 1 (PRL-1) and phosphatase of regenerating liver 3 (PRL-3) in transitional cell carcinoma of bladder (BTCC) and normal epithelia of bladder was investigated, and the relationship between the BTCC and pathological changes was clarified. The expression of PRL-1 and PRL-3 mRNA was detected by using reverse transcription polymerase chain reaction (RT-PCR) in 30 cases of BTCC and 10 cases of normal bladder, and the expression of PRL-1 and PRL-3 protein was checked by using immunohistochemistry in 30 cases of BTCC and 15 cases of normal bladder. The expression levels of PRL-1 and PRL-3 mRNA and protein were higher in BTCC than those in normal bladder epithelia ( <0.05). The increased expression of PRL-1 and PRL-3 mRNA and protein was detectable in deep invasion and metastasis of BTCC ( <0.05). There was no correlation between the expression of PRL-1 and PRL-3 and gender, age or recurrence of BTCC (all >0.05). A significantly positive correlation was found between PRL-1 and PRL-3 in BTCC ( <0.05). PRL-1 and PRL-3 are expressed consistently and may contribute to the growth, differentiation, invasion and metastasis of BTCC.

关键词： transitional cell carcinoma of bladder phosphatase of regenerating liver 1 phosphatase of regenerating liver 3 reverse transcription polymerase chain reaction immunohistochemistry

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Review on research and application of mesoporous transitional metal oxides in water treatment

Minghao SUI, Lei SHE

《环境科学与工程前沿（英文）》 2013年第7卷第6期页码 795-802 doi: 10.1007/s11783-013-0521-4

摘要： This paper reviews the application of mesoporous transitional metal oxides in water treatment on basis of the catalysis and adsorption. Mesoporous transitional metal oxides are characterized by their intrinsic features, such as a high surface area, a highly ordered array of unidimensional pores with a very narrow pore size distribution, and highly dispersed active sites. Finally, the suggestions of further study on application are proposed.

关键词： mesoporous materials transitional metal oxides catalysis adsorption water treatment

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Development of combined transitional pavement structure for urban tram track-road grade crossings

《结构与土木工程前沿（英文）》页码 1199-1210 doi: 10.1007/s11709-023-0949-y

摘要： The grade crossings and adjacent pavements of urban trams are generally subjected to complex load conditions and are susceptible to damage. Therefore, in this study, a novel pavement structure between tram tracks and roads constructed using polyurethane (PU) elastic concrete and ultra-high-performance concrete (UHPC), referred to as a track-road transitional pavement (TRTP), is proposed. Subsequently, its performance and feasibility are evaluated using experimental and numerical methods. First, the mechanical properties of the PU elastic concrete are evaluated. The performance of the proposed structure is investigated using a three-dimensional finite element model, where vehicle-induced dynamic and static loads are considered. The results show that PU elastic concrete and the proposed combined TRTP are applicable and functioned as intended. Additionally, the PU elastic concrete achieved sufficient performance. The recommended width of the TRTP is approximately 50 mm. Meanwhile, the application of UHPC under a PU elastic concrete layer significantly reduces vertical deformation. Results of numerical calculations confirmed the high structural performance and feasibility of the proposed TRTP. Finally, material performance standards are recommended to provide guidance for pavement design and the construction of tram-grade crossings in the future.

关键词： urban tram track grade crossing combined track-road transitional pavement polyurethane elastic concrete finite element method

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Robust optimization of the billet for isothermal local loading transitional region of a Ti-alloy rib-web

Ke WEI, Xiaoguang FAN, Mei ZHAN, Miao MENG

《机械工程前沿（英文）》 2018年第13卷第3期页码 376-384 doi: 10.1007/s11465-018-0500-3

摘要：

Billet optimization can greatly improve the forming quality of the transitional region in the isothermal local loading forming (ILLF) of large-scale Ti-alloy rib-web components. However, the final quality of the transitional region may be deteriorated by uncontrollable factors, such as the manufacturing tolerance of the preforming billet, fluctuation of the stroke length, and friction factor. Thus, a dual-response surface method (RSM)-based robust optimization of the billet was proposed to address the uncontrollable factors in transitional region of the ILLF. Given that the die underfilling and folding defect are two key factors that influence the forming quality of the transitional region, minimizing the mean and standard deviation of the die underfilling rate and avoiding folding defect were defined as the objective function and constraint condition in robust optimization. Then, the cross array design was constructed, a dual-RSM model was established for the mean and standard deviation of the die underfilling rate by considering the size parameters of the billet and uncontrollable factors. Subsequently, an optimum solution was derived to achieve the robust optimization of the billet. A case study on robust optimization was conducted. Good results were attained for improving the die filling and avoiding folding defect, suggesting that the robust optimization of the billet in the transitional region of the ILLF was efficient and reliable.

关键词： isothermal local loading forming rib-web component transitional region robust optimization dual response surface method

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Development of environmental management system in China's financial sector

CHANG Miao, PENG Lijuan, WANG Shiwen

《环境科学与工程前沿（英文）》 2008年第2卷第2期页码 172-177 doi: 10.1007/s11783-008-0032-x

摘要： The establishment of the environmental management system in the financial sector can be effectively promoted through the introduction of the environmental protection concept and its implementation by the financial sector. The impact of a sustainable development system on the sector is analyzed in this article from three aspects: environmental risk assessment, financing support for environmental protection projects, and financial services to environmentally friendly corporations and individuals. Influential factors on the development of the environmental management system in China’s financial sector are discussed from the perspective of various entities such as financial institutions, financial regulation authorities, environmental protection departments, corporations, and the public. It is pointed out that China’s financial sector is now in the transitional phase from a defensive attitude to a preventive attitude. Strengthening governmental guidance, the supervision of regulators as well as public awareness of environmental protection should be used to enhance the initiative in the development of the environmental management system in the Chinese financial sector.

关键词： perspective s financial financial ’ s transitional