Journal Home Online First Current Issue Archive For Authors Journal Information 中文版

Strategic Study of CAE >> 2017, Volume 19, Issue 2 doi: 10.15302/J-SSCAE-2017.02.018

The Status and Control Strategy of Bacterial Resistance in China

Department of Burn Surgery, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

Funding project:中国工程院咨询项目“我国耐药致病菌及菌群紊乱态势和防控策略研究”(2015-XY-26) Received: 2017-01-15 Revised: 2017-03-13 Available online: 2017-05-03 10:07:28.000

Next Previous

Abstract

Bacterial resistance, a growing public concern worldwide, poses a threat to the health of humans, other animals, and the environment. This paper presents the status of bacterial resistance in various fields in China, analyzes the main cause of such resistance, and reveals the serious damage being caused to public health, food safety, the ecological environment, and economic development. We also summarize China's actions in containing antimicrobial resistance, and this country's main achievements. Finally, to address issues in bacterial resistance surveillance, antibiotics stewardship, hazard evaluation, and talent team building, this paper puts forward a national control strategy that calls for the collaborative effort of multiple disciplines.

References

[ 1 ] World Health Organization. Global action plan on antimicrobial resistance [R]. Geneva: WHO, 2015.

[ 2 ] G20 Leaders’ Communique Hangzhou summit [J]. China Eco-nomic Weekly, 2016 (36): 98–105. Chinese. link1

[ 3 ] World Health Organization. United Nations high-level meeting on antimicrobial resistance [EB/OL]. (2016-08-05) [2016-11-21]. http://www.who.int/mediacentre/events/2016/antimicrobial-re-sis-tance/zh/. Chinese.

[ 4 ] Hu F P, Zhu D M, Wang F, et al. CHINET 2014 surveillance of bacterial resistance in China [J]. Chinese Journal of Infection and Chemotherapy, 2015, 15(5): 401–410. Chinese.

[ 5 ] Tian L, Chen Z J, Sun Z Y, et al. Antibiotic resistance profile of enterobacter in hospitals across China: Data from CHINET an-ti-microbial resistance surveillance program from 2005 through 2014Chinese Journal of Infection and Chemotherapy, 2016, 16(3): 275–283. Chinese. link1

[ 6 ] Zhang H, Zhang X J, Xv Y C, et al. Resistance profile of acineto-bacter isolates in hospitals across China: Results from CHINET antimicrobial resistance surveillance program 2005–2014 Chinese Journal of Infection and Chemotherapy, 2016, 16(4): 429–436. Chinese. link1

[ 7 ] Xv A, Zhuo C, Su D H, et al. Changing susceptibility of klebsiella strains in hospitals across China: Data from the CHINET anti-mi-crobial resistance surveillance program 2005–2014 [J]. Chinese Journal of Infection and Chemotherapy, 2016, 16(3): 267–274. Chinese. link1

[ 8 ] Committee of Experts on Rational Drug Use, National Health and Family Planning Commission of the P.R.China, and China An-ti-microbial Resistance Surveillance System. China antimicrobial 116The Status and Control Strategy of Bacterial Resistance in Chinaresistance surveillance system report 2015 [J]. China Licensed Pharmacist, 2016, 13(3): 3–8. Chinese.

[ 9 ] Shen J Z. The risk and prevention of antimicrobial resistance among pathogenic bacteria from food animals. Proceedings of the National Health Technology Forum [C]. Yantai: China National Center for Biotechnology Development, 2009. Chinese.

[10] Jiang H, Lv D, Chen Z, et al. High prevalence and widespread distribution of multi-resistant escherichia coli isolates in pigs and poultry in China [J]. The Veterinary Journal, 2011, 187(1): 99–103. link1

[11] Pal C, Bengtsson-Palme J, Kristiansson E, et al. The structure and diversity of human, animal and environmental resistances [J]. Mi-crobiome, 2016, 4(1): 54. link1

[12] Van Boeckel T P, Gandra S, Ashok A, et al. Global antibiotic con-sumption 2000 to 2010: An analysis of national pharmaceu-tical sales data [J]. The Lancet Infectious Diseases, 2014, 14(8): 742–750. link1

[13] Wang J, Wang P, Wang X, et al. Use and prescription of antibiotics in primary health care settings in China [J]. JAMA Internal Me-di-cine, 2014, 174(12): 1914–1920. link1

[14] Zhang Q, Ying G, Pan C, et al. Comprehensive evaluation of an-ti-biotics emission and fate in the river basins of China: Source anal-ysis, multimedia modeling, and linkage to bacterial resistance [J]. Environmental Science & Technology, 2015, 49(11): 6772–6782. link1

[15] Van Boeckel T P, Brower C, Gilbert M, et al. Global trends in antimicrobial use in food animals [J]. Proceedings of the National Academy of Sciences, 2015, 112(18): 5649–5654. link1

[16] Finley R L, Collignon P, Larsson D G J, et al. The scourge of antibiotic resistance: The important role of the environment [J]. Clinical Infectious Diseases, 2013, 57(5): 704–710. link1

[17] Xiong W, Sun Y, Zhang T, et al. Antibiotics, antibiotic resistance genes, and bacterial community composition in fresh water aqua- culture environment in China [J]. Microbial Ecology, 2015, 70(2): 425–432. link1

[18] Wang H X, Wang B, Zhao Q, et al. Antibiotic body burden of Chi-nese school children: A multisite biomonitoring-based study [J]. Environmental Science & Technology, 2015, 49(8): 5070–5079. link1

[19] O’Neill J. Review on antimicrobial resistance – antimicrobial re-sistance: Tackling a crisis for the health and wealth of nations [EB/OL]. (2014-12-16) [2016-10-25].

[20] World Bank. Drug-resistant infections: A threat to our economic future (discussion draft) [EB/OL]. (2016-03-20) [2016-10-25].

[21] Xiao Y, Zhang J, Zheng B, et al. Changes in Chinese policies to promote the rational use of antibiotics [J]. PLoS Medicine, 2013, 10(11): e1001556. link1

[22] National Health and Family Planning Commission of the PRC. Antimicrobial management will be enhanced in multi areas [EB/OL]. (2015-11-19) [2016-11-22]. http://www.nhfpc.gov.cn/xcs/wzbd/201511/5f5da3a6792c479aa91cd05e2328d836.shtml. Chinese.

[23] Ministry of Agriculture of the PRC. Five year action plan for the comprehensive management of veterinary drugs in China (2015–2019) [EB/OL]. (2015-07-23) [2016-11-23]. http://www.moa.gov.cn/govpublic/ncpzlaq/201507/t20150723_4759838.htm. Chinese.

[24] National Health and Family Planning Commission of the PRC. National action plan for contain antimicrobial resistance (2016–2020) [EB/OL]. (2016-08-25) [2016-11-23]. http://www.moh.gov.cn/yzygj/s3593/201608/f1ed26a0c8774e1c8fc89dd481ec84d7.shtml. Chinese.

Related Research