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Bacteria-mediated tumor-targeted delivery of tumstatin (54-132) significantly suppresses tumor growth in mouse model by inhibiting angiogenesis and promoting apoptosis

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 873-882 doi: 10.1007/s11684-022-0925-2

Abstract: VNP20009, an attenuated Salmonella typhimurium strain, preferentially accumulates in the hypoxicIn this study, a novel Salmonella-mediated targeted expression system of tumstatin (VNP-Tum5)Treatment with VNP-Tum5 effectively suppressed tumor growth and prolonged survival in the mouse modelof B16F10 cells in vitro and in vivo compared with VNP (control).This study is the first to use tumstatin-transformed VNP20009 as a tumor-targeted system for treatment

Keywords： Salmonella VNP20009     tumstatin     B16F10     melanoma     apoptosis     angiogenesis    

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Salmonella-Delivered COBRA-HA1 Antigen Derived from H1N1 Hemagglutinin Sequences Elicits Broad-Spectrum Article

Ram Prasad Aganja, Amal Senevirathne, Chandran Sivasankar, John Hwa Lee

Engineering 2024, Volume 32, Issue 1,   Pages 42-57 doi: 10.1016/j.eng.2023.08.001

Abstract: Constructs carrying different HA1 regions were delivered into eukaryotic cells by SalmonellaThis discovery revolutionizes influenza vaccine design and delivery; Salmonella-mediated COBRA-HA1

Keywords： COBRA     Influenza A     Salmonella     Vaccine     Broad spectral protection    

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Genomic Epidemiology of ST34 Monophasic Salmonella enterica Serovar Typhimurium from Clinical Patients Article

Yujiao Mu, Ruichao Li, Pengcheng Du, Pei Zhang, Yan Li, Shenghui Cui, Séamus Fanning, Li Bai

Engineering 2022, Volume 15, Issue 8,   Pages 34-44 doi: 10.1016/j.eng.2022.05.006

Abstract:

Salmonella enterica serovar 4,[5],12:i:- (S. 4,[5],12:i:-) is a monophasic variant of Salmonella enterica serovar Typhimurium that has emerged

Keywords： Salmonella Typhimurium monophasic variant     ST34     Prevalence     Phylogenetic analysis     Chinese lineages    

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Quantum Dot Nanobeads-Labelled Lateral Flow Immunoassay Strip for Rapid and Sensitive Detection of Salmonella Article

Yuting Shang,Shuzhen Cai,Qinghua Ye,Qingping Wu,Yanna Shao,Xiaoying Qu,Xinran Xiang,Baoqing Zhou,Yu Ding,Moutong Chen,Liang Xue,Honghui Zhu,Jumei Zhang

Engineering 2022, Volume 19, Issue 12,   Pages 62-70 doi: 10.1016/j.eng.2021.03.024

Abstract: combined with strand displacement loop-mediated isothermal amplification (SD-LAMP) for quantitative Salmonella

Keywords： Salmonella     Typhimurium     Quantum dot nanobeads     Lateral flow immunoassay strip     Loop-mediated isothermal    

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Title Author Date Type Operation

Bacteria-mediated tumor-targeted delivery of tumstatin (54-132) significantly suppresses tumor growth in mouse model by inhibiting angiogenesis and promoting apoptosis

Journal Article

Salmonella-Delivered COBRA-HA1 Antigen Derived from H1N1 Hemagglutinin Sequences Elicits Broad-Spectrum

Ram Prasad Aganja, Amal Senevirathne, Chandran Sivasankar, John Hwa Lee

Journal Article

Genomic Epidemiology of ST34 Monophasic Salmonella enterica Serovar Typhimurium from Clinical Patients

Yujiao Mu, Ruichao Li, Pengcheng Du, Pei Zhang, Yan Li, Shenghui Cui, Séamus Fanning, Li Bai

Journal Article

Quantum Dot Nanobeads-Labelled Lateral Flow Immunoassay Strip for Rapid and Sensitive Detection of Salmonella

Yuting Shang,Shuzhen Cai,Qinghua Ye,Qingping Wu,Yanna Shao,Xiaoying Qu,Xinran Xiang,Baoqing Zhou,Yu Ding,Moutong Chen,Liang Xue,Honghui Zhu,Jumei Zhang

Journal Article

Bai Li: Epidemic Characteristics and Population Exposure Risk of Newly Developed Drug-resistant Salmonella

17 Oct 2022

Conference Videos