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2019 1

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CRNDE 1

alternative splicing 1

long noncoding RNA 1

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Overexpressed long noncoding RNA CRNDE with distinct alternatively spliced isoforms in multiple cancers

Xuefei Ma, Wei Zhang, Rong Zhang, Jingming Li, Shufen Li, Yunlin Ma, Wen Jin, Kankan Wang

Frontiers of Medicine 2019, Volume 13, Issue 3,   Pages 330-343 doi: 10.1007/s11684-017-0557-0

Abstract: CRNDE is a long noncoding RNA with alternative splicing and is implicated in the pathogenesis of severalHowever, whether deregulated expression of CRNDE is common and which isoforms are mainly involved inIn this study, we report that CRNDE is aberrantly expressed in the majority of solid and hematopoieticThe investigation of CRNDE expression in normal samples revealed that CRNDE was expressed in a tissueprimary samples, and even had different impacts on the expression of CRNDE isoforms.

Keywords： long noncoding RNA     CRNDE     alternative splicing    

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Overexpressed long noncoding RNA CRNDE with distinct alternatively spliced isoforms in multiple cancers

Xuefei Ma, Wei Zhang, Rong Zhang, Jingming Li, Shufen Li, Yunlin Ma, Wen Jin, Kankan Wang

Journal Article