Search scope:
排序: Display mode:
Utility of transbronchial biopsy in the diagnosis of lymphangioleiomyomatosis
Riffat Meraj, Kathryn A. Wikenheiser-Brokamp, Lisa R. Young, Sue Byrnes, Francis X. McCormack
Frontiers of Medicine 2012, Volume 6, Issue 4, Pages 395-405 doi: 10.1007/s11684-012-0231-5
Pulmonary lymphangioleiomyomatosis (LAM) is a rare cystic lung disease that targets women during their reproductive years. A confident diagnosis can often be based on clinical grounds, but diagnostic certainty requires pathological analysis. Although surgical lung biopsy is considered the gold standard for obtaining tissue in patients with diffuse lung disease, it is also associated with higher morbidity and mortality than alternative, less invasive techniques. The objective of our study was to examine the utility of transbronchial biopsy in the diagnosis of LAM. We conducted two online surveys of over 1 000 LAM patients registered with the LAM Foundation who were accessible by email. Transbronchial biopsy specimens were subsequently collected and reviewed by an expert pathologist to validate the diagnosis. We found that transbronchial biopsy has a yield of approximately 60% in patients with LAM. We conclude that transbronchial biopsy may be a safe and effective method for establishing the diagnosis of LAM, obviating the need for surgical lung biopsy in more than half of LAM patients.
Keywords: disease diffuse cystic lung disease transbronchial biopsy perivascular epithelioid cell tumor (PEComa) HMB-45-45
Stability and dynamics of rotor system with 45° slant crack on shaft
Yanli LIN, Xiaohui SI, Fulei CHU
Frontiers of Mechanical Engineering 2011, Volume 6, Issue 2, Pages 203-213 doi: 10.1007/s11465-011-0131-4
Keywords: rotor dynamics slant crack stability torsional excitation open and close
Controllability of fractional-order damped systems with time-varying delays in control Research Articles
Bin-bin He, Hua-cheng Zhou, Chun-hai Kou,hebinbin45@126.com,hczhou@amss.ac.cn,kouchunhai@dhu.edu.cn
Frontiers of Information Technology & Electronic Engineering 2020, Volume 21, Issue 6, Pages 809-962 doi: 10.1631/FITEE.1900736
Keywords: 可控性;分数阶阻尼系统;时变时滞;Gramian矩阵
Title Author Date Type Operation
Utility of transbronchial biopsy in the diagnosis of lymphangioleiomyomatosis
Riffat Meraj, Kathryn A. Wikenheiser-Brokamp, Lisa R. Young, Sue Byrnes, Francis X. McCormack
Journal Article
Stability and dynamics of rotor system with 45° slant crack on shaft
Yanli LIN, Xiaohui SI, Fulei CHU
Journal Article