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Acetylated HOXB9 at lysine 27 is of differential diagnostic value in patients with pancreatic ductal adenocarcinoma

Xiaoran Sun, Jiagui Song, Jing Zhang, Jun Zhan, Weigang Fang, Hongquan Zhang

Frontiers of Medicine 2020, Volume 14, Issue 1,   Pages 91-100 doi: 10.1007/s11684-019-0696-6

Abstract: Pancreatic ductal adenocarcinoma (PDAC) is the ninth most common human malignancy and the sixth leadingHowever, the role of AcK27-HOXB9 in PDAC is unclear.HOXB9 promoted ( =0.0115), while AcK27-HOXB9 ( =0.0279) inhibited PDAC progression.AcK27-HOXB9 predicted favorable outcome in patients with PDAC ( =0.0412).AcK27-HOXB9 also suppressed PDAC cell migration in a cell migration assay.

Keywords： HOXB9     AcK27-HOXB9     PDAC    

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Acetylated HOXB9 at lysine 27 is of differential diagnostic value in patients with pancreatic ductal adenocarcinoma

Xiaoran Sun, Jiagui Song, Jing Zhang, Jun Zhan, Weigang Fang, Hongquan Zhang

Journal Article