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Journal Article 1

Year

2009 1

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CD437 1

apoptosis 1

celecoxib 1

cycle arrest 1

melanoma A375 cell 1

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Celecoxib in combination with retinoid CD437 inhibits melanoma A375 cell

Jianwen REN, Zhenhui PENG, Birong GUO, Min PAN

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 108-112 doi: 10.1007/s11684-009-0015-8

Abstract: This study aimed to investigate the effects of celecoxib, synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenylCelecoxib at 80 μmol/L inhibited proliferation, induced apoptosis and G /M cell cycle arrest of humanCelecoxib in combination with CD437 could significantly enhance the effects of inhibiting proliferationCelecoxib could inhibit the growth of human malignant melanoma A375 cells by inducing apoptosis and GCelecoxib exhibited additive effects with CD437 on retarding the growth and inducing apoptosis of human

Keywords： celecoxib     CD437     melanoma A375 cell     apoptosis     cycle arrest    

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Celecoxib in combination with retinoid CD437 inhibits melanoma A375 cell

Jianwen REN, Zhenhui PENG, Birong GUO, Min PAN

Journal Article