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Immunological effects of nano-enabled hyperthermia for solid tumors: opportunity and challenge

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 3, Pages 333-344 doi: 10.1007/s11705-021-2059-5

Abstract: Compared to conventional hyperthermia that is limited by low selectivity and severe side effects, nano-enabledhyperthermia yields great potentials to tackle these limitations for cancer treatment.Another major advance is the observation of immunological responses associated with nano-enabled hyperthermiatemperature-gradient and the spatially-structured immunological landscape in solid tumors receiving nano-enabled hyperthermiamicroenvironment, including the creative design of nano-enabled combination therapy to synergize with nano-enabled hyperthermia

Keywords： nano-enabled hyperthermia immunogenic cell death heterogeneous immunological landscape tumor microenvironment

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Hyperthermia on skin immune system and its application in the treatment of human papillomavirus-infected

Xinghua Gao, Hongduo Chen

Frontiers of Medicine 2014, Volume 8, Issue 1, Pages 1-5 doi: 10.1007/s11684-014-0309-3

Abstract:

Hyperthermia is a condition characterized by increased body temperature as a consequence of failedHyperthermia occurs when a body produces or absorbs more heat than it dissipates.Hyperthermia also elicits various effects on the physiology of living cells.The immunomodulatory effect of hyperthermia has promoted an interest in hyperthermia-aided immunotherapyHyperthermia has also been used to treat deep fungal, bacterial, and viral skin infections.

Keywords： hyperthermia HPV immune response virus tumor