Resource Type

Journal Article 1

Year

2012 1

Keywords

antidepressant 1

brain-derived neurotrophic factor 1

ketamine 1

tramadol 1

tropomyosin-related kinase B 1

Search scope:

排序: Display mode:

Tramadol reinforces antidepressant effects of ketamine with increased levels of brain-derived neurotrophic

Chun Yang, Xiaomin Li, Nan Wang, Shixia Xu, Jianjun Yang, Zhiqiang Zhou

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 411-415 doi: 10.1007/s11684-012-0226-2

Abstract:

Ketamine exerts rapid and robust antidepressant properties in both animal models and depressed patientsWe hypothesized that tramadol pretreatment might reinforce ketamine-elicited antidepressant effects withHowever, pretreatment with tramadol (5 mg/kg) enhanced the ketamine (10 mg/kg) -elicited antidepressantIn conclusion, tramadol pretreatment reinforces the ketamine-elicited antidepressant effects, which is

Keywords: tramadol     ketamine     antidepressant     brain-derived neurotrophic factor     tropomyosin-related kinase B    

Title Author Date Type Operation

Tramadol reinforces antidepressant effects of ketamine with increased levels of brain-derived neurotrophic

Chun Yang, Xiaomin Li, Nan Wang, Shixia Xu, Jianjun Yang, Zhiqiang Zhou

Journal Article