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bio-macromolecular drugs 1

cell penetrating peptides 1

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Developing macromolecular therapeutics: the future drug-of-choice

Huining HE, Victor C. YANG, Weibing DONG, Junbo GONG, Jingkang WANG,

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 1, Pages 10-17 doi: 10.1007/s11705-009-0291-5

Abstract: Macromolecular drugs including peptides, proteins, antibodies, polysaccharides and nucleic acids haveDue to their unmatched properties of high selectivity and efficiency, macromolecular drugs have beenSince worldwide progress on macromolecular therapeutics still remains in the infant stage and is thereforewide open for equal-ground competition, R&D related to macromolecular drugs should be consideredstrategies and drug delivery approaches that should be adopted to enhance the therapeutic effects of macromolecular

Keywords： worldwide challenging effective macromolecular self-owned intellectual

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Significance and strategies in developing delivery systems for bio-macromolecular drugs

Huining HE, Qiuling LIANG, Meong Cheol SHIN, Kyuri LEE, Junbo GONG, Junxiao YE, Quan LIU, Jingkang WANG, Victor YANG

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 4, Pages 496-507 doi: 10.1007/s11705-013-1362-1

Abstract: unmatched reaction efficiency and a repetitive action mode, the therapeutic activity of a single bio-macromolecularHence, bio-macromolecular drugs have been recognized around the world as the future “drug-of-choice”.Yet, among the>10000 drugs that are currently available, only ~150 of them belong to these bio-macromolecularIn general, the bottleneck limitations of these bio-macromolecular drugs are two-fold: (1) the absenceSince worldwide progress on bio-macromolecular therapeutics still remains in the infant stage and thus

Keywords： delivery systems bio-macromolecular drugs cell penetrating peptides

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Synthesis and characterization of macromolecular surface modifier PP--PEG for polypropylene

CHEN Hanjia, SHI Xuhua, ZHU Yafei, ZHANG Yi, XU Jiarui

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 1, Pages 102-108 doi: 10.1007/s11705-008-0018-z

Abstract: A novel macromolecular surface modifier, polypropylene-grafted-poly(ethylene glycol) copolymer (PP--PEGthat PP--PEG could diffuse preferably onto the surface of the blends and be suitable as an effectual macromolecular

Keywords： polypropylene crystallization capacity attenuated hydrophilicity reflectance