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Liu Li,Wu Chunlin,Hu Yajun
Strategic Study of CAE 2015, Volume 17, Issue 6, Pages 31-35
Objective：To find out the general clinical characteristics from patients with normal ovulation，small follicular ovulation and luteinized unruptured follicle and observe the result of ovulation detection repeatedly and the effect of ovarian stimulatioin for later two types. Methods：Retrospective analyzing the difference of the patients’age，basal serum gonadal steroid hormones and follicle size before ovulation in the groups of normal ovulation（n=258）， small follicular ovulation（n=65）and luteinized unruptured follicle（n=27）. Then we observed the result of ovulation detection repeatedly by transvaginal ultrasound in the latter two groups. Finally，the ovulation induction with clomiphene citrate was carried out in the 58 cases of small follicles ovulation and 25 cases of luteinizing unruptured follicle which obtained the consistent results during the twice ovulation detection，we observed the rates of normal ovulation and clinical pregnancy in the two types of ovulatory dysfunctions. Results：Average age and basal serum Gonadal steroid hormones levelsdid not have significant difference（P<0.01）in thegroups of normal ovulation，small follicular ovulation and luteinized unruptured follicle，average diameter of follicles before ovulation in the three groups had significant difference（F=117.9，P< 0.01）. Incidence rates of small follicular ovulation and luteinized unruptured follicle were 18.5 % and 7.71 % respectively. Both were detected repeatedly，repetition rates were 89.23 % and 92.59 % respectively. After combined induced ovulation by clomiphene withluteal support， normal ovulation rates were 70.69 % and 80 % in the groups of small follicular ovulation and unruptured follicle ovulation luteinized respectively，clinical pregnancy rateswere 29.31 % and 48 % respectively. Conclusions：Small follicular ovulation and luteinized unruptured follicle are two special types of ovulatory dysfunctions，basal serum gonadal steroid hormones levels cannot predict ovulation，and transvaginal ultrasound is the most direct method to diagnosisthe small follicular ovulation and luteinized unruptured follicle. Without treatment，the repetition rate is high in thetwo types of ovulatory dysfunctions. Combined induced ovulation withluteal support is effective in the patients of the small follicular ovulation and luteinized unruptured follicle.
Keywords： transvaginalultrasound ovulation detection small follicular ovulation luteinized unruptured follicle
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