Disruptive technologies that lead industrial change have many characteristics, including technological breakthrough, product substitution, market universality, and industrial transformation, all of which have profound impact on social development and people's lives. First, from the industry and technology perspectives, this article proposes the connotation and selection of disruptive technologies that lead industrial change. Next, the corresponding index evaluation system is established. Lastly, through two rounds of questionnaire surveys utilizing qualitative and quantitative methods, this article selects approximately 20 disruptive technologies that are currently leading the industrial change; subsequent analysis provides support for further study on the law between disruptive technology and the industrial revolution, as well as carrying out technical forecasting.