Disruptive technology has become an important driving force for economic and social development and military revolution. Strengthening disruptive technological innovation is particularly important in realizing development transformation and future strategic initiative in China. The Chinese Academy of Engineering has set up a major advisory project "Strategic Research on Disruptive Technologies in Engineering Science and Technology". This project is aimed to plan the development of disruptive technologies in engineering science and technology in China. The paper systematically introduces the research objectives, contents, and methods of this project, and summarizes the progresses in disruptive technology concept study, forecasting and identifying methods, tracking and early warning of worldwide disruptive technologies, and identification and evaluation of major disruptive technology directions. Meanwhile, the paper also summarizes the experiences and deficiencies in project implementation. All the research contents of the project provide a useful reference for the national strategic research on disruptive technology.