The concept of disruptive technology has been widely used since it was introduced. And there is no uniform definition due to different research perspectives. Since disruptive technology has transformative effects of defining times and reconstructing patterns, it plays increasingly significant role in national strategy. Understanding disruptive technology from the national perspective has a practical guiding significance in the development of disruptive technology. After explorations on the concept of disruptive technology from different perspectives, this paper points out that developing disruptive technology from the national perspective opens up a new technology trajectory based on new principles, combinations, and applications of science and technologies. It is a strategic innovative technology that will reorganize value network of the traditional industries, decisively affect the upgrading of social technology systems, or reconstruct present national foundations, capabilities, and structure. Furthermore, a deconstruction framework of disruptive technology is proposed from the perspectives of source, structure, span, scale, level, and path. On this basis, to develop disruptive technology, this paper proposed to focus on the combination of frontier research and practical use, the process, the balance between reality and future, innovative management modes, and strategic research.