This paper introduces the four stages of independent innovation in Weichai’s 20 years of development. Combined with the research and development of core technologies for the commercial vehicle powertrain system, this paper expounds the understandings of and typical experiences in the innovative development of commercial vehicle powertrain system. It also provides an outlook for the future development of commercial vehicles from the aspects of high-efficiency low-emission internal combustion engines, new energy application, and intelligent connected technology, and shares the future planning and practices of Weichai in the traditional energy and new energy business area.