Nuclear fuel cycle standardization is important for the safe and innovative development of the nuclear fuel cycle industry, especially when China has currently entered a high-quality development stage. Therefore, conducting strategic research on nuclear fuel cycle standardization becomes significant for boosting China’s nuclear industry. In this article, we analyze the development status of nuclear fuel cycle standardization in China and abroad, investigate the key problems of nuclear fuel cycle standardization in China from the perspectives of working mechanism, development balance, leading role, and support ability, and propose the major tasks and relevant countermeasures. Specifically, the major tasks involve seven aspects: post-stage standards of the nuclear fuel cycle, standards for key technologies, advanced standards, frontier basic standards, safety and environmental protection standards, international standardization, and basic capacities for standardization. Furthermore, the countermeasures comprise including nuclear fuel cycle standardization into the 14th Five-Year Plan of the nuclear industry, improving the standardization mechanism, increasing investment, and strengthening the construction of standardization talent teams.