Mine disaster science is a systematic science for mine safety and disaster reduction. It is,compared with the previous unitary prevention and treatment of mine disaster, characterized by the comprehensiveness, prediction and economic nature. It involves 8 aspects of safety and disaster reduction,such as safety philosophy , safety economics ,etc. The research pattern embodies the principle of unity between the macroscopic and the microscopic. The research should be under the guidance of the system-theory. While exploring the preventing and treatment technology and method for the individual case of mine disaster,the research should be pitched into with multi discipline,at different levels and from different directions.