The impropriety industrial production mode is one of the main causes of environmental pollution. From thermodynamics, this paper analyses the entropy essential of the pollution of industrial production. On the basis of this, a dynamic equilibrium entropy flow model is set up to measure the infection of industrial production to the environment. Taking three production modes for example, the entropy increase quantity is calculated by using the model and the environmental effect trends can be educed. It can provide decision-making basis for choice of sustainable production mode.