A new-generation, three-dimensional observing network on the plateau and its peripheral may not only provide a strong precursor for the development of regional disastrous weather and climate events downstream, but may also provide crucial information on cross-hemispheric energy and water cycle and global climate change. In view of the roles of the Tibetan Plateau as the upstream key region for flooding, heavy rainfall, and snowstorms in a large area of eastern China, and the most sensitive region for climate change on the global scale, a plan for setting up an observing network and application of new technology has been proposed. We have designed and constructed this new-generation observing network on the Tibetan Plateau and its peripheral regions. The development of this new observing network has gone through a path of scientific experiment engineering construction- operation application. In particular, utilizing a north-south line of observational data from GPS and AWS stations on the east fringe of the Plateau, we were able to assimilate these data into the WRF(weather research and forcaits) 3Dvar system. The ensuing predictive results indicated that the upstream observations enhanced the ability for numerical prediction of summer heavy rainfall in eastern China and winter snowstorms in south China. Verifications suggested that the observing network had a significant impact on the early warning of disastrous weather events downstream.