Filling solution cavity of high pressure and rich water have the characteristics features of abundant water, high pressure,large scale and complicated filling medium. Its engineering construction risk is extremely high. The conventional grouting method is affected by inhomogeneity stratum, the choices of material and technique level, so the grouting blind area is difficult to avoid. Once the grouting blind area is breakdown by high pressure water during the process of construction, It will generate large-scale water and mud outburst which cause a disaster. By tackling key problems in science and technology, adopting the energesis and depressurization technology is advanced to father filling solution cavity of high pressure and rich water on Yichang-Wanzhou Railway.It is safe, economical, credible and successful by local practice. The energesis and depressurization technology is adopting arranged and purposeful cccurate–blasting to open out solution cavity, to release storaged energy, to reduce tunnel's influence by water pressure during the process of construction and to finish farthering solution cavity by related measures.