2 882 samples were taken in Qinghai- Tibet railway cars, and 1 693 samples were taken out randomly, then the factors that may affect the ability of individual' s hypoxia- resistant were analyzed in statistics. This paper has done this work by nonparametric statistics and correlation analysis , and got the conclusion that five factors, which are mountain sickness one have suffered before, sex, smoking frequency, bodily form and age, influence individual' s hypoxia- resistant ability. The conclusion makes a good sense, as it can provide statistics foundation for continuous iatrical research, while giving directive suggestion to reduce passengers' mountain sickness, and providing warranty for the design and amelioration of oxygen supplying system in Qinghai- Tibet railway cars .