Puguang Gas Field is characteristic of deep reservior, long hole interval to be perforated and rich H2S. These features brings risks to perforation and operation safety. This paper presents the choice of perforation technology, defination of perforating gun and perforation parameters, selection of sulfide resistance material, tubing protection, design of ignition and detonation propagation reliability related to technical problems and dificulties on perforation operation in Puguang gas field. The perforation effectiveness analysis shows such technical designs can satisfy the requirement of acid fracturing after perforating in Puguang gas field as using anti-sulfur 114 perforators and changing the perforation density. Tubing tripping can be prevented effectively by using some technical measures such as different tubing thickness combination, partition time delayed perforation, combination of longitudinal shock absorber and radial direction shock absorber. Enhancement type fixed bullet system can meet the request of reliable detonation of long-channel perforation.