Taizhou Changjiang River Highway Bridge is a suspension bridge with three towers, two spans and two anchorages. The main span is 2×1 080 m. The south and north foundation of the anchorages are deep water caisson with rectangular plane size 67.9 m×52.0 m. A great many of technical innovations are adopted to solve many technical problems including the disposal of the compound basement, manufacturing and installation of the caisson, fulfillment of concrete in the caisson etc, based on the conditions such as the thick overburden layer at the top of the caisson, the super dimension and the big sinking depth of the caisson. This article gives a brief introduction on construction technologies in huge caisson on the ground and can be taken as a reference during the construction of the super scale caisson on the ground in the future.