According to the practical reservoir characteristics of the study area, the feasibility of horizontal wells development was analyzed, and the result showed that the reservoir characteristics of study area were suit to develop horizontal wells. Based on the establishment of three-dimensional fine geological modeling of study area, using numerical simulation, the well network pattern, length of the horizontal section, well spacing, row spacing and development indicators were predicted. The simulation result showed that the optimal well network was the symmetrical horizontal section, and the horizontal well had echelonment horizontal sections traversing the two layers of Mawu12 and Mawu13, and the well spacing and row spacing were both 2 100 m. The result of development indicators prediction showed that, after 10 years, the recovery percentage was 48.78 %, which was 16.6 % higher than that of vertical wells. The study result can guide the study area to develop efficiently.