Nuclear energy is a carbon-free,  clean and efficient energy. It is very important in the progress of human civilization and modern development of the world. However,  there are still some problems such as nuclear leak and nuclear waste. In this paper,  the world's nuclear energy utilization and nuclear power plant constructions are reviewed and plans are forecasted. The basic reason of previous nuclear power plant accidents in history is summarized. Taking 2011 Tohuku earthquake -fukushima nuclear power station accident as an example, threats to the nuclear power plant by earthquake are investigated and impacts on social,  economic and ecological environment caused by nuclear power station accident are analyzed. This paper drew lessons from previous accidents and put forward a variety of countermeasures which are from both the technical and management aspects. This paper also put forward some suggestions. Security measures of the existing nuclear power plants should be assessed carefully. The long-term construction plan of the nuclear power plant should be improved. In addition,  emergency management mechanism of the nuclear power plant can be enhanced in the future. The earthquake monitoring and earthquake early-warning system is critical and promoted to be established widely. The nuclear probability safety analysis (PSA) could be investigated in depth. The security education of the public should be continuously popularized and disaster drills be carried out regularly. International cooperation and communication are also advocated to be strengthened. All these measures can be significant in human process to explore nuclear energy correctly. We also appeal people all over the world to respect the nature,  enjoy the nature,  and to create and enjoy the new civilization of human beings.