In recent years, frequent haze weather makes PM2.5 becoming the public hotspot. The control of PM2.5 has been added in the 2012 release "ambient air quality standard". Under the situation that our current flue gas pollutant control technology is difficult to remove PM2.5, the development of the Flue Gas Pollutants Deep-removal Technology (DRT) for Coal-fired Power Plant for deep-removing PM2.5, SO2, SO3, heavy metals and other pollutants, is becoming an urgent problem. Basing on the analysis of the necessity and existing problems of developing DRT suitable for China, this study focused on the PM2.5 removal technology, low NOx emission of ultra supercritical boiler under full load, and the adaptability of SCR working temperature. Finally, introduces the flue gas pollutant removal system with an example of a 2×660 MW supercritical power plant, and analyses the Roadmap of development of DRT for 1 000 MW ultra supercritical unit.