Nowadays membrane technology has been widely employed in the treatment of industrial wastewater and municipal sewage. In the last decade， plenty of work focused on the preparation and industrialization of advanced polyvinylidene fluoride (PVDF) membranes with excellent performance has been carried out by the Chemical Engineering Department in Tsinghua University， which follows the line of preparation formula design， advanced production and membrane module development. This paper reviewed the history information about these researches. Firstly， PVDF membranes with good performance were prepared via thermally induced phase separation (TIPS) method based on thermodynamic and dynamic researches on the membrane formation process. Secondly， advanced production of PVDF hollow-fiber membrane was achieved by an effective combination of material processing and unit operation. Finally， different modules were designed and fabricated according to the characteristic of PVDF membrane prepared via TIPS method and different application situations. The results show that the PVDF membranes prepared via TIPS method break through the traditional phase separation limitation and exceed performance expectation； as a result TIPS method can be the top option for wastewater treatment.