Research on Bionic Fungicide Yintai and Its Application

2007, Volume 9, Issue 3

Abstract

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Strategic Study of CAE >> 2007, Volume 9, Issue 3

Research on Bionic Fungicide Yintai and Its Application

1. Department of Architectural Engineering, Xinyang Normal University, Xinyang, Henan, 464000, China;

2. School of Civil Engineering and Mechanics, Huazhong University of Science and Technology, Wuhan, 430074, China

Received: 2006-05-26 Revised: 2006-08-01

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Abstract

Yintai (p-hydroxy butrophenone) is a kind of bionic fungicides synthesized by simulating the lead compound of ginkgol isolated from the exosperm of ginkgo fruit. 8.3-time diluted solution of alcohol crude extract from the ginkgo fruit showed 100% inhibtion on the pathogen of apple canker (Valsa mali), and 50% inhibition for the 25-time solution. Both 200-time and400time solutions of ginkgol, extracted from external seed coat of ginkgo, had 100% inhibition on pathogen of apple canker(Valsa mali). EC₅₀ of 20% Yintai ME against4kinds of pathogens, including apple canker, tomato gray mold, and so on, ranges from 17.26 mg/L to 48.43 mg/L, better than the contrast chemicals respectively. Field control effects on4kinds of diseases, e.g. , Rhizoctonia cerealis, are higher than 85%, with safety to non-target organisms, and no symptom of pesticide resistance. Both LD50of acute oral toxicity and LD₅₀of acute dermal toxicity to mouse are 4640 mg/kg by Yintai technical material, and 3160 mg/kg and 2150 mg/kg by 20% Yintai EC coorespondingly. Trials of subchronic toxicity (90days) revealed that oral toxicity was 19.1 mg/kg for female, and 18.3 mg/kg for male, with negative results on Ames test, micro-nucleus test, and chromosome-type aberration test.

Keywords

Ginkgo biloba L. ; ginkgol ; bionic synthesis ; Yintai ; control effect

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