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Role of the forkhead transcription factor FOXO-FOXM1 axis in cancer and drug resistance
Fung Zhao, Eric W.-F. Lam
Frontiers of Medicine 2012, Volume 6, Issue 4, Pages 376-380 doi: 10.1007/s11684-012-0228-0
The forkhead transcription factors FOXO and FOXM1 have pivotal roles in tumorigenesis and in mediatingforkhead transcription factor FOXM1 is a direct transcriptional target repressed by the forkhead protein FOXO3a, a vital downstream effector of the PI3K-AKT-FOXO signaling pathway.Intriguingly, FOXM1 and FOXO3a also compete for binding to the same gene targets, which have a role inAn understanding of the role and regulation of the FOXO-FOXM1 axis will impact directly on our knowledge
Keywords: FOXO3a FOXM1 transcription factor cancer drug resistance tumorigenesis
Xifan Wang,Pengjie Wang,Yixuan Li,Huiyuan Guo,Ran Wang,Siyuan Liu,Ju Qiu,Xiaoyu Wang,Yanling Hao,Yunyi Zhao,Haiping Liao,Zhongju Zou,Josephine Thinwa,Rong Liu,
Engineering doi: 10.1016/j.eng.2023.10.016
Keywords: Inflammatory bowel disease Mucosal Barrier Autophagy
YE Lin, ZHAO Yumei, FENG Zengguo, BAI Ying, WU Feng
Frontiers of Chemical Science and Engineering 2007, Volume 1, Issue 4, Pages 343-348 doi: 10.1007/s11705-007-0062-0
Keywords: 4-butanediol 2-methoxyethylenoxy consistent oxetane-derived copolymer
Heterologous expression of signal protein 14-3-3 in and the subsequent immune response in mice
ZHENG Meijuan, SHEN Jilong, LUO Qingli, XU Yuanhong
Frontiers of Medicine 2008, Volume 2, Issue 1, Pages 95-99 doi: 10.1007/s11684-008-0017-y
Keywords: development challenging rSj14-3-3 resistance cultural supernatant
Conference Date: 12 Mar 2020
Conference Place: 广东广州
Administered by: HP3C 2020
FOXP3 and Its Cofactors as Targets of Immunotherapies Review
Yasuhiro Nagai,Lian Lam,Mark I. Greene,Hongtao Zhang
Engineering 2019, Volume 5, Issue 1, Pages 115-121 doi: 10.1016/j.eng.2019.01.001
Forkhead box P3 (FOXP3) is a "master regulator" of regulatory T cells (Tregs), which areAs a consequence, the PTMs change the stability of FOXP3 and its capability to regulate gene expressionAlthough FOXP3 per se is not an ideal drug target, deacetylases, acetyltransferases, kinases, and other enzymes that regulate the PTMs of FOXP3 are potential targets to modulate FOXP3 and TregFOXP3" side effects must be considered when inhibitors to these enzymes are used.
Keywords: Treg Forkhead box P3 (FOXP3) Post-translational modification Autoimmune Cancer
Conference Date: 12 Mar 2020
Conference Place: 海南海口 三亚
Administered by: APISE
Frontiers of Medicine 2024, Volume 18, Issue 1, Pages 180-191 doi: 10.1007/s11684-023-1003-0
Keywords: Lipin3 Lipin1 hypertriglyceridemia obesity mitochondrial dysfunction
A Review on the 3D Printing of Functional Structures for Medical Phantoms and Regenerated Tissue and
Kan Wang, Chia-Che Ho, Chuck Zhang, Ben Wang
Engineering 2017, Volume 3, Issue 5, Pages 653-662 doi: 10.1016/J.ENG.2017.05.013
Keywords: 3D printing 3D bioprinting Medical phantom Regenerated tissue/organ Scaffold
Deep3DSketch-im: rapid high-fidelity AI 3D model generation by single freehand sketches Research Article
Tianrun CHEN;Runlong CAO;Zejian LI;Ying ZANG;Lingyun SUN;
Frontiers of Information Technology & Electronic Engineering 2024, Volume 25, Issue 1, Pages 149-159 doi: 10.1631/FITEE.2300314
Keywords: Content creation Sketch Three-dimensional (3D) modeling 3D reconstruction Shape from X Artificial
Influence and related mechanism of Retn gene expression on glucose uptake in 3T3-L1 cells
LI Yahui, DONG Shiyuan, YU Chao, JIANG Yu, LI Huaixing, SUN Shuhan
Frontiers of Medicine 2007, Volume 1, Issue 3, Pages 269-273 doi: 10.1007/s11684-007-0051-1
Keywords: 3T3-L1 influence resistance receptor substrate-1 transport
3D-printable self-healing biodegradable materials and their applications
Frontiers of Mechanical Engineering 2024, Volume 19, Issue 3, doi: 10.1007/s11465-024-0787-1
Combustion and emissions of RP-3 jet fuel and diesel fuel in a single-cylinder diesel engine
Frontiers in Energy 2023, Volume 17, Issue 5, Pages 664-677 doi: 10.1007/s11708-021-0787-3
Keywords: RP-3 jet fuel diesel engine combustion emissions
China Engineering Science 2001 Volume 3 Contents
Strategic Study of CAE 2001, Volume 3, Issue 12, Pages 96-99
Title Author Date Type Operation
Role of the forkhead transcription factor FOXO-FOXM1 axis in cancer and drug resistance
Fung Zhao, Eric W.-F. Lam
Journal Article
Procyanidin C1 Modulates the Microbiome to Increase FOXO1 Signaling and Valeric Acid Levels to Protect
Xifan Wang,Pengjie Wang,Yixuan Li,Huiyuan Guo,Ran Wang,Siyuan Liu,Ju Qiu,Xiaoyu Wang,Yanling Hao,Yunyi Zhao,Haiping Liao,Zhongju Zou,Josephine Thinwa,Rong Liu,
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Xiaohan: Traditional Chinese Medicine Talks About Health, Dietary Supplement and Improving Immunity (2020-3-
18 Apr 2022
Conference Videos
Synthesis of copolymers of 3-acryloyloxymethyl-3′-methyloxetane and 3-(2-(2-(2-Methoxyethylenoxy)ethylenoxy)ethylenoxy)-3′-methyloxetane and their ionic conductivity properties
YE Lin, ZHAO Yumei, FENG Zengguo, BAI Ying, WU Feng
Journal Article
Heterologous expression of signal protein 14-3-3 in and the subsequent immune response in mice
ZHENG Meijuan, SHEN Jilong, LUO Qingli, XU Yuanhong
Journal Article
第四届高性能编译、计算和通信国际会议(HP3C 2020)
12 Mar 2020
Conference Information
FOXP3 and Its Cofactors as Targets of Immunotherapies
Yasuhiro Nagai,Lian Lam,Mark I. Greene,Hongtao Zhang
Journal Article
2020第四届环境与能源工程国际会议(IC3E 2020)
12 Mar 2020
Conference Information
Haploinsufficiency of Lipin3 leads to hypertriglyceridemia and obesity by disrupting the expression and
Journal Article
A Review on the 3D Printing of Functional Structures for Medical Phantoms and Regenerated Tissue and
Kan Wang, Chia-Che Ho, Chuck Zhang, Ben Wang
Journal Article
Deep3DSketch-im: rapid high-fidelity AI 3D model generation by single freehand sketches
Tianrun CHEN;Runlong CAO;Zejian LI;Ying ZANG;Lingyun SUN;
Journal Article
Influence and related mechanism of Retn gene expression on glucose uptake in 3T3-L1 cells
LI Yahui, DONG Shiyuan, YU Chao, JIANG Yu, LI Huaixing, SUN Shuhan
Journal Article
Combustion and emissions of RP-3 jet fuel and diesel fuel in a single-cylinder diesel engine
Journal Article