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Daniel Wai-Hung Ho,Alan Ka-Lun Kai,Irene Oi-Lin Ng
Frontiers of Medicine 2015, Volume 9, Issue 3, Pages 322-330 doi: 10.1007/s11684-015-0408-9
This study systematically evaluates the TCGA whole-transcriptome sequencing data of hepatocellular
Keywords: TCGA whole-transcriptome sequencing HCC liver cancer
Exploring the cancer genome in the era of next-generation sequencing
Hui Dong, Shengyue Wang
Frontiers of Medicine 2012, Volume 6, Issue 1, Pages 48-55 doi: 10.1007/s11684-012-0182-x
The emergence of next-generation sequencing technologies has led to dramatic advances in cancer genomeThe increased efficiency and resolution of next-generation sequencing greatly facilitate the detectionComprehensive analysis of cancer genomes through approaches of whole genome, exome, and transcriptomesequencing has significantly improved the understanding of cancer biology, diagnosis, and therapy.The present study briefly reviews the recent pioneering studies on cancer genome sequencing and provides
Keywords: next-generation sequencing cancer genome whole genome sequencing exome transcriptome
Frontiers of Medicine doi: 10.1007/s11684-023-0994-x
Keywords: primary central nervous system lymphoma whole-genome sequencing TMSB4X copy number variation
Exome sequencing greatly expedites the progressive research of Mendelian diseases
Xuejun Zhang
Frontiers of Medicine 2014, Volume 8, Issue 1, Pages 42-57 doi: 10.1007/s11684-014-0303-9
The advent of whole-exome sequencing (WES) has facilitated the discovery of rare structure and functionalCombining exome sequencing with linkage studies is one of the most efficient strategies in searchingWe illustrate the workflow of exome capture and sequencing to highlight the advantages of WES.
Keywords: genetics whole-exome sequencing Mendelian disease disease gene
Biao Kan, Haijian Zhou, Pengcheng Du, Wen Zhang, Xin Lu, Tian Qin, Jianguo Xu
Frontiers of Medicine 2018, Volume 12, Issue 1, Pages 23-33 doi: 10.1007/s11684-017-0607-7
Two decades have passed since the first bacterial whole-genome sequencing, which provides new opportunityIn recent years, genome sequencing techniques and bioinformatics have developed rapidly, which has resultedBacterial whole-genome sequencing and bioinformatic computing allow genotyping to satisfy the requirementsIn this review, we outline the significance and summarize the roles of bacterial genome sequencing inWide applications of genome sequencing and data sharing in infectious disease surveillance networks will
Keywords: genome sequencing genomic epidemiology bacteria surveillance infectious diseases
Lijuan Hu,Zhirui Lin,Yanheng Wu,Juqin Dong,Bo Zhao,Yanbing Cheng,Peiyu Huang,Lihua Xu,Tianliang Xia,Dan Xiong,Hongbo Wang,Manzhi Li,Ling Guo,Elliott Kieff,Yixin Zeng,Qian Zhong,Musheng Zeng
Frontiers of Medicine 2016, Volume 10, Issue 1, Pages 61-75 doi: 10.1007/s11684-016-0436-0
Keywords: Epstein-Barr virus paired-end transcriptome sequencing latency genes lytic genes nasopharyngeal carcinoma
Plastic materials and water sources actively select and shape wastewater plastispheres over time
Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 11, doi: 10.1007/s11783-022-1580-1
● Wastewater MPs exhibited resistomes and therefore health threats.
Keywords: Microplastics Whole-genome metagenomic sequencing Plastisphere Plastic degradation MHETase
A novel variant in the gene in a large Chinese family with a unique phenotype of Clouston syndrome
Frontiers of Medicine 2023, Volume 17, Issue 2, Pages 330-338 doi: 10.1007/s11684-022-0933-2
Keywords: Clouston syndrome whole exome sequencing GJB6 gene novel variant unique phenotype
Transcriptome resources and genome-wide marker development for Japanese larch (
Wanfeng LI,Suying HAN,Liwang QI,Shougong ZHANG
Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 1, Pages 77-84 doi: 10.15302/J-FASE-2014010
Keywords: Larix transcriptome age wood formation somatic embryogenesis molecular marker
Hongyuan ZHAO, Shanshan ZHANG, Feibing WANG, Ning ZHAO, Shaozhen HE, Qingchang LIU, Hong ZHAI
Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 2, Pages 214-225 doi: 10.15302/J-FASE-2018219
Keywords: anthocyanin gene expression mutant purple-fleshed sweet potato transcriptome
Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 2,
Frontiers of Engineering Management Pages 439-454 doi: 10.1007/s42524-022-0211-7
Keywords: megaproject organizational evolution whole lifecycle management project management team
Cell surface protein engineering for high-performance whole-cell catalysts
Hajime Nakatani,Katsutoshi Hori
Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 1, Pages 46-57 doi: 10.1007/s11705-017-1609-3
Keywords: cell surface engineering surface display whole-cell catalysts bioprocess
Yan Zhang, Shuting Wang, He Xia, Jing Guo, Kangxin He, Chenjie Huang, Rui Luo, Yanfei Chen, Kaijin Xu, Hainv Gao, Jifang Sheng, Lanjuan Li
Engineering 2022, Volume 17, Issue 10, Pages 161-169 doi: 10.1016/j.eng.2021.05.009
Keywords: COVID-19 Severe infection Critically ill Monocytes Fibrosis
Efficient acetoin production from pyruvate by engineered whole-cell biocatalysis
Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 4, Pages 425-436 doi: 10.1007/s11705-022-2229-0
Keywords: -acetolactate synthetase α-acetolactate decarboxylase Halomonas bluephagenesis whole-cell
Title Author Date Type Operation
TCGA whole-transcriptome sequencing data reveals significantly dysregulated genes and signaling pathways
Daniel Wai-Hung Ho,Alan Ka-Lun Kai,Irene Oi-Lin Ng
Journal Article
Exploring the cancer genome in the era of next-generation sequencing
Hui Dong, Shengyue Wang
Journal Article
Analysis of the genomic landscape of primary central nervous system lymphoma using whole-genome sequencing
Journal Article
Exome sequencing greatly expedites the progressive research of Mendelian diseases
Xuejun Zhang
Journal Article
Transforming bacterial disease surveillance and investigation using whole-genome sequence to probe the
Biao Kan, Haijian Zhou, Pengcheng Du, Wen Zhang, Xin Lu, Tian Qin, Jianguo Xu
Journal Article
Comprehensive profiling of EBV gene expression in nasopharyngeal carcinoma through paired-end transcriptomesequencing
Lijuan Hu,Zhirui Lin,Yanheng Wu,Juqin Dong,Bo Zhao,Yanbing Cheng,Peiyu Huang,Lihua Xu,Tianliang Xia,Dan Xiong,Hongbo Wang,Manzhi Li,Ling Guo,Elliott Kieff,Yixin Zeng,Qian Zhong,Musheng Zeng
Journal Article
Plastic materials and water sources actively select and shape wastewater plastispheres over time
Journal Article
A novel variant in the gene in a large Chinese family with a unique phenotype of Clouston syndrome
Journal Article
Transcriptome resources and genome-wide marker development for Japanese larch (
Wanfeng LI,Suying HAN,Liwang QI,Shougong ZHANG
Journal Article
Comparative transcriptome analysis of purple-fleshed sweet potato provides insights into the molecular
Hongyuan ZHAO, Shanshan ZHANG, Feibing WANG, Ning ZHAO, Shaozhen HE, Qingchang LIU, Hong ZHAI
Journal Article
METABOLIC AND TRANSCRIPTOME ANALYSIS REVEALS METABOLITE VARIATION AND FLAVONOID REGULATORY NETWORKS IN
Journal Article
Organizational evolution of project management teams over the whole lifecycle of megaprojects: Case study
Journal Article
Cell surface protein engineering for high-performance whole-cell catalysts
Hajime Nakatani,Katsutoshi Hori
Journal Article
Monocytes Associated with Severe COVID-19 in the PBMCs of Severely Infected Patients Through Single-Cell TranscriptomeSequencing
Yan Zhang, Shuting Wang, He Xia, Jing Guo, Kangxin He, Chenjie Huang, Rui Luo, Yanfei Chen, Kaijin Xu, Hainv Gao, Jifang Sheng, Lanjuan Li
Journal Article