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《中国工程科学》 >> 2003年 第5卷 第7期

抗RNA病毒相关生物材料

1.天津大学高分子材料研究所,天津 300072

2.天津城建学院材料系,天津 300384

收稿日期: 2003-05-15 发布日期: 2003-07-20

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摘要

在介绍RNA病毒结构、生殖、复制和转录的基础上,综述了抗病毒策略,其中包括抗SARS药物设计,RNA干扰,DNA疫苗释放系统,调控蛋白与糖胺聚糖衍生物或类似物相互作用,天然药物及肺泡组织工程等。这些实例涵盖了RNA病毒与蛋白质、DNA及多糖等生物材料的相互作用。生物材料作为基质或载体正在向细胞或/和基因活化的第三代生物材料发展,可望在抗病毒中发挥作用。

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