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Toward deep impacts of BIM on education
Žiga TURK, Andreja ISTENIČ STARČIČ
《工程管理前沿(英文)》 2020年 第7卷 第1期 页码 81-88 doi: 10.1007/s42524-019-0035-2
关键词: engineering education building information modelling engineering communication curriculum development
DQB1*060101 may contribute to susceptibility to immunoglobulin A nephropathy in southern Han Chinese
null
《医学前沿(英文)》 2016年 第10卷 第4期 页码 507-516 doi: 10.1007/s11684-016-0475-6
Immunoglobulin A nephropathy (IgAN) is a common form of chronic glomerulonephritis with unknown pathogenesis. Accumulating evidences have shown the ethnic-specific association between certain human leukocyte antigen (HLA) alleles and IgAN susceptibility. This study was designed to explore the relationship between HLA-DQB1 alleles and disease susceptibility and clinical manifestations of patients with IgAN in southern Han Chinese. A PCR sequence-based typing technique was used to detect HLA-DQB1 alleles in 217 IgAN patients and 229 healthy subjects. Clinical data were collected from each patient at the time of renal biopsy. Twenty HLA-DQB1 alleles were detected in IgAN patients and healthy subjects. High frequency of HLA-DQB1*060101 and low frequency of HLA-DQB1*030101 were observed in IgAN patients compared with healthy controls. Further stratification analysis revealed that the frequency of DQB1*060101 was significantly higher in patients with urine protein≥1.0 g/24 h than in patients with urine protein<1.0 g/24 h. In combination with our previous DRB1 results, we also analyzed the association of DRB1-DQB1 haplotypes with IgAN. We found that the frequency of haplotype DRB1*090102-DQB1*060101 was significantly higher [odds ratio (OR) = 4.409, Pc = 0.016], whereas that of HLA-DRB1*070101-DQB1*020101 was significantly lower (OR= 0.194, Pc = 0.016) compared with healthy controls. Our study indicated that HLA-DQB1*060101 alleles may be a potential predictor of high-risk IgAN susceptibility in Chinese Han population.
关键词: DQB1 human leukocyte antigen (HLA) IgA nephropathy haplotype association study
Tran Quoc THAI, Timon RABCZUK, Xiaoying ZHUANG
《结构与土木工程前沿(英文)》 2020年 第14卷 第2期 页码 267-279 doi: 10.1007/s11709-019-0567-x
关键词: cohesive zone model IGA Kirchhoff-Love model thin shell analysis delamination
IGA
《化学科学与工程前沿(英文)》 2013年 第7卷 第4期 页码 482-489 doi: 10.1007/s11705-013-1342-5
关键词: pectic extracts antiproliferative activity breast cancer enzymatic treatment
标题 作者 时间 类型 操作
Toward deep impacts of BIM on education
Žiga TURK, Andreja ISTENIČ STARČIČ
期刊论文
DQB1*060101 may contribute to susceptibility to immunoglobulin A nephropathy in southern Han Chinese
null
期刊论文
Isogeometric cohesive zone model for thin shell delamination analysis based on Kirchhoff-Love shell model
Tran Quoc THAI, Timon RABCZUK, Xiaoying ZHUANG
期刊论文