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Genome-wide association study of the backfat thickness trait in two pig populations

Dandan ZHU,Xiaolei LIU,Rothschild MAX,Zhiwu ZHANG,Shuhong ZHAO,Bin FAN

《农业科学与工程前沿（英文）》 2014年 第1卷 第2期   页码 91-95 doi: 10.15302/J-FASE-2014005

摘要： Backfat thickness is a good predictor of carcass lean content, an economically important trait, and a main breeding target in pig improvement. In this study, the candidate genes and genomic regions associated with the tenth rib backfat thickness trait were identified in two independent pig populations, using a genome-wide association study of porcine 60K SNP genotype data applying the compressed mixed linear model (CMLM) statistical method. For each population, 30 most significant single-nucleotide polymorphisms (SNPs) were selected and SNP annotation implemented using Build 10.2. In the first population, 25 significant SNPs were distributed on seven chromosomes, and SNPs on SSC1 and SSC7 showed great significance for fat deposition. The most significant SNP (ALGA0006623) was located on SSC1, upstream of the gene. In the second population, 27 significant SNPs were recognized by annotation, and 12 SNPs on SSC12 were related to fat deposition. Two haplotype blocks, M1GA0016251-MARC0075799 and ALGA0065251-MARC0014203-M1GA0016298-ALGA0065308, were detected in significant regions where the and genes were identified as contributing to fat metabolism. The results indicated that genetic mechanism regulating backfat thickness is complex, and that genome-wide associations can be affected by populations with different genetic backgrounds.

关键词： backfat thickness     SNP chip     genome-wide association study     compressed mixed linear model     pig    

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Effects of sheet thickness and material on the mechanical properties of flat clinched joint

Chao CHEN, Huiyang ZHANG, Shengdun ZHAO, Xiaoqiang REN

《机械工程前沿（英文）》 2021年 第16卷 第2期   页码 410-419 doi: 10.1007/s11465-020-0618-y

摘要： The flat clinching process is attracting a growing attention in the joining field of lightweight materials because it avoids the geometric protrusion that appears in the conventional clinching process. In this paper, the effects of sheet thickness and material on the mechanical properties of the clinched joint were studied. Al1060 and Al2024 sheets with 2 mm thickness were employed to develop the clinched joint by using different material configurations, and Al1060 sheets with 2.5- and 1.5-mm thicknesses were used to produce the clinched joint by using different thickness configurations. The clinched joints using various sheet configurations were sectioned, and dimensional analysis was conducted. Cross-tensile and shearing tests were carried out to analyze the mechanical properties of the clinched joint, including tensile strength, shearing strength, and absorbed energy. In addition, the failure modes of the clinched joints were discussed. Results indicated that the clinched joint with a stiff top sheet had increased static strength regardless of the test type. The clinched joint with a thick top sheet demonstrated lower static strength than the joint with a thick bottom sheet in the cross-tensile test. However, this result was reversed in the shearing tests. The flat clinching process has a great potential in joining dissimilar and various thickness materials.

关键词： clinched joint     flat clinching process     thickness configuration     material configuration     mechanical property    

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Lamellar thickness transition of melt-crystallized polybuten-1 tetragonal phase: configurational change

Motoi YAMASHITA

《化学科学与工程前沿（英文）》 2009年 第3卷 第1期   页码 26-32 doi: 10.1007/s11705-009-0002-2

摘要： Lamellar crystal thickness of isotactic polybutene-1 ( -PB1) have been investigated for crystallization in the melt over a wide range of crystallization temperature from 40°C to 90°C by small angle X-ray scattering experiments and density measurements. The crystal thickness demonstrates two linear dependences on inverse supercooling and a transition from one dependence to the other has been observed around = 65°C. Each of the two dependences obeys the nucleation theory in the high and low supercooling ranges, respectively. Chain folding free energy determined from the low supercooling range is larger than that determined from the high supercooling range. Possible mechanisms for the transition are discussed taking account of entropy of chain folding directions.

关键词： isotactic polybutene-1     tetragonal phase     crystal thickness     melt growth     chain folding     small angle X-ray scattering     nucleation theory     end surface free energy    

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Modeling of the minimum cutting thickness in micro cutting with consideration of the friction around

Tianfeng ZHOU, Ying WANG, Benshuai RUAN, Zhiqiang LIANG, Xibin WANG

《机械工程前沿（英文）》 2020年 第15卷 第1期   页码 81-88 doi: 10.1007/s11465-019-0561-y

摘要： Friction modeling between the tool and the workpiece plays an important role in predicting the minimum cutting thickness during TC4 micro machining and finite element method (FEM) cutting simulation. In this study, a new three-region friction modeling is proposed to illustrate the material flow mechanism around the friction zone in micro cutting; estimate the stress distributions on the rake, edge, and clearance faces of the tool; and predict the stagnation point location and the minimum cutting thickness. The friction modeling is established by determining the distribution of normal and shear stress. Then, it is applied to calculate the stagnation point location on the edge face and predict the minimum cutting thickness. The stagnation point and the minimum cutting thickness are also observed and illustrated in the FEM simulation. Micro cutting experiments are conducted to validate the accuracy of the friction and the minimum cutting thickness modeling. Comparison results show that the proposed friction model illustrates the relationship between the normal and sheer stress on the tool surface, thereby validating the modeling method of the minimum cutting thickness in micro cutting.

关键词： tool friction     minimum cutting thickness     finite element method     tool edge radius     micro cutting    

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Numerical simulation of compaction parameters for sand-filled embankment using large thickness sand filling

Wentao WANG, Chongzhi TU, Rong LUO

《结构与土木工程前沿（英文）》 2018年 第12卷 第4期   页码 568-576 doi: 10.1007/s11709-017-0444-4

摘要： The study uses the finite element method to simulate a new technique of highway sand embankment filling in Jianghan Plain district, which can raise the thickness of sand-filled layer from 30 cm to 70 cm and can significantly shorten the construction period based on the guarantee of sand embankment construction quality. After simulating the three compacting proposals carried out on the field test, the study uses COMSOL software to research on the compacting effects of sand-filled layers in larger thicknesses by 22 ton vibratory roller alone, and then to investigate the steady compacting effect of 12 ton vibratory roller. The simulation results indicate that the sand-filled layer thickness of 70 cm is suitable for the new sand filling technique, and the sand-filled embankment project with tight construction period is suggested to choose the 12 ton vibration roller for steady compaction.

关键词： sand embankment     compaction in large thickness     numerical simulation     small size vibratory roller     steady compaction    

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Determining the optimum economic insulation thickness of double pipes buried in the soil for district

Fating LI, Pengfei JIE, Zhou FANG, Zhimei WEN

《能源前沿（英文）》 2021年 第15卷 第1期   页码 170-185 doi: 10.1007/s11708-020-0680-5

摘要： The insulation thickness (IT) of double pipes buried in the soil (DPBIS) for district heating (DH) systems was optimized to minimize the annual total cost of DPBIS for DH systems. An optimization model to obtain the optimum insulation thickness (OIT) and minimum annual total cost (MATC) of DPBIS for DH systems was established. The zero point theorem and fsolve function were used to solve the optimization model. Three types of heat sources, four operating strategies, three kinds of insulation materials, three buried depth (BD) values, and seven nominal pipe size (NPS) values were considered in the calculation of the OIT and MATC of DPBIS for DH systems, respectively. The optimization results for the above factors were compared. The results show that the OIT and MATC of DPBIS for DH systems can be obtained by using the optimization model. Sensitivity analysis was conducted to investigate the impact of some economic parameters, i.e., unit heating cost, insulation material price, interest rate, and insulation material lifetime, on optimization results. It is found out that the impact of sensitivity factors on the OIT and MATC of DPBIS for DH systems is different.

关键词： double pipes     optimization model     optimum insulation thickness     minimum annual total cost    

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Time of flight improved thermally grown oxide thickness measurement with terahertz spectroscopy

《机械工程前沿（英文）》 2022年 第17卷 第4期 doi: 10.1007/s11465-022-0705-3

摘要： As a nondestructive testing technique, terahertz time-domain spectroscopy technology is commonly used to measure the thickness of ceramic coat in thermal barrier coatings (TBCs). However, the invisibility of ceramic/thermally grown oxide (TGO) reflective wave leads to the measurement failure of natural growth TGO whose thickness is below 10 μm in TBCs. To detect and monitor TGO in the emergence stage, a time of flight (TOF) improved TGO thickness measurement method is proposed. A simulative investigation on propagation characteristics of terahertz shows the linear relationship between TGO thickness and phase shift of feature wave. The accurate TOF increment could be acquired from wavelet soft threshold and cross-correlation function with negative effect reduction of environmental noise and system oscillation. Thus, the TGO thickness could be obtained efficiently from the TOF increment of the monitor area with different heating times. The averaged error of 1.61 μm in experimental results demonstrates the highly accurate and robust measurement of the proposed method, making it attractive for condition monitoring and life prediction of TBCs.

关键词： thermal barrier coatings     thermally grown oxide     terahertz spectroscopy     time of flight    

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Optimizing environmental insulation thickness of buildings with CHP-based district heating system based

Yumei ZHANG, Pengfei JIE, Chunhua LIU, Jing LI

《能源前沿（英文）》 2022年 第16卷 第4期   页码 613-628 doi: 10.1007/s11708-020-0700-5

摘要： The increase of insulation thickness (IT) results in the decrease of the heat demand and heat medium temperature. A mathematical model on the optimum environmental insulation thickness (OEIT) for minimizing the annual total environmental impact was established based on the amount of energy and energy grade reduction. Besides, a case study was conducted based on a residential community with a combined heat and power (CHP)-based district heating system (DHS) in Tianjin, China. Moreover, the effect of IT on heat demand, heat medium temperature, exhaust heat, extracted heat, coal consumption, carbon dioxide (CO ) emissions and sulfur dioxide (SO ) emissions as well as the effect of three types of insulation materials (i.e., expanded polystyrene, rock wool and glass wool) on the OEIT and minimum annual total environmental impact were studied. The results reveal that the optimization model can be used to determine the OEIT. When the OEIT of expanded polystyrene, rock wool and glass wool is used, the annual total environmental impact can be reduced by 84.563%, 83.211%, and 86.104%, respectively. It can be found that glass wool is more beneficial to the environment compared with expanded polystyrene and rock wool.

关键词： optimum environmental insulation thickness     heat medium temperature     energy grade     extracted heat     exhaust heat    

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The ITZ microstructure, thickness, porosity and its relation with compressive and flexural strength of

《结构与土木工程前沿（英文）》 2022年 第16卷 第2期   页码 191-201 doi: 10.1007/s11709-021-0792-y

摘要： A new insight into the interfacial transition zone (ITZ) in cement mortar specimens (CMSs) that is influenced by cement fineness is reported. The importance of cement fineness in ITZ characterizations such as morphology and thickness is elucidated by backscattered electron images and by consequences to the compressive (Fc) and flexural strength (Ff), and porosity at various water/cement ratios. The findings indicate that by increasing the cement fineness the calcium silicate hydrate formation in the ITZ is favored and that this can refine the pore structures and create a denser and more homogeneous microstructure. By increasing cement fineness by about 25% of, the ITZ thickness of CMSs was reduced by about 30% and Fc was increased by 7%–52% and Ff by 19%–40%. These findings illustrate that the influence of ITZ features on the mechanical strength of CMSs is mostly related to the cement fineness and ITZ microstructure.

关键词： cement fineness     interfacial transition zone     compressive and flexural strength    

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Eddy current measurement of the thickness of top Cu film of the multilayer interconnects in the integrated

Zilian QU,Yonggang MENG,Qian ZHAO

《机械工程前沿（英文）》 2015年 第10卷 第1期   页码 1-6 doi: 10.1007/s11465-015-0325-2

摘要：

This paper proposes a new eddy current method, named equivalent unit method (EUM), for the thickness measurement of the top copper film of multilayer interconnects in the chemical mechanical polishing (CMP) process, which is an important step in the integrated circuit (IC) manufacturing. The influence of the underneath circuit layers on the eddy current is modeled and treated as an equivalent film thickness. By subtracting this equivalent film component, the accuracy of the thickness measurement of the top copper layer with an eddy current sensor is improved and the absolute error is 3 nm for sampler measurement.

关键词： CMP     eddy current     multilayer wafer     Cu interconnects     equivalent unit    

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numerical studies on concrete encased trapezoidally web profiled cold formed steel beams by varying depth-thickness

Divahar RAVI, Aravind Raj PONSUBBIAH, Sangeetha Sreekumar PRABHA, Joanna Philip SARATHA

《结构与土木工程前沿（英文）》 2020年 第14卷 第4期   页码 930-946 doi: 10.1007/s11709-020-0652-1

摘要： Concrete encased with trapezoidally corrugated web profiled cold-formed steel beams are used worldwide to improve resistance toward fire and corrosion, higher load carrying capacity as well as significant increase in the bending stiffness by encasing concrete on the beam portion. The present work gives a detailed description on the experimental, analytical and numerical investigation on the flexural behavior of concrete encased trapezoidally corrugated web profiled cold-formed steel beams which were simply supported at both ends and subjected to two point symmetric loading. The flexural behavior of such structure has been experimentally tested to failure under pure bending. To find the effect of concrete encasement in the web, 12 experiments were conducted by two different series. Beams having three different web corrugation angles of 0°, 30°, and 45° with two different web depth-thickness ( / ) ratios of 60 and 80 were tested. Experimental results such as load-deflection relationship, ultimate capacity, load-strain relationship, moment-curvature curves, ductility and failure mode indices of the specimens are presented. From the static bending tests the concrete encased trapezoidally corrugated web beam showed improved moment carrying capacity, ductility behavior and the resistance to transverse deflections in comparison to concrete encased with plain web beam. Especially for the beams with concrete encased 30° trapezoidally corrugated web having ( / ) ratio 60 and 80, the loading capacity was improved about 54% and 67.3% and the ductility also increased about 1.6 and 3.6 times, when compared to concrete encased beams with plain web. This research should contribute to the future engineering applications on seismic resistant structures and efficient usage of concrete encased with cold-formed steel beams by exhibiting its super elasto-plastic property. The analytical and numerical results showed good agreement with the experimental results at yield load, which indicates that the proposed analytical equations can be applied in predicting flexural strength accurately for such concrete encased trapezoidally corrugated web profiled cold-formed steel beams.

关键词： concrete encased beam     trapezoidally corrugated web     loading capacity     super elasto-plastic    

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Elastoplastic frictional contact problem study on interference fits of compressor

ZHANG Hongwu, WU Changhua, LIAO Aihua

《能源前沿（英文）》 2008年 第2卷 第3期   页码 313-319 doi: 10.1007/s11708-008-0026-1

摘要： The FE parametric quadratic programming (PQP) method developed from the parametric variational principle (PVP) was used for the analysis of the stress distribution of the 3D elastoplastic frictional contact of an impeller-shaft sleeve-shaft. A locomotive-type turbocharger compressor with 24 blades under combined centrifugal and interference-fit loading was considered in the numerical analysis. The solution of elastoplastic frictional contact problems belongs to unspecified boundary problems where the interaction between two kinds of nonlinearities should occur. To save time in the numerical computation, a multi-substructure technique was adopted in the structural modeling. The effect of fit tolerance, wall thickness of the shaft sleeve, and rotational speed on the contact stress was discussed in detail in the numerical computation. To decrease the difficulty of the assembly process and ensure the safety of the working state, the amount of interference between the shaft sleeve and shaft by press-fitting should be controlled strictly to avoid the rapid increase of contact stress. The numerical results show that the algorithm has high accuracy and good convergence. The study can be referred to in deciding the proper fit tolerance and improving the design and manufacturing technology of compressor impellers.

关键词： computation     thickness     interference-fit     interference     unspecified    

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产氧缝合线介导的氧气全层渗透用于促进移植皮肤的存活 Article

宰文静, 袁雨浓, 康琳, 许加龙, 胡一桥, 康立峰, 吴锦慧

《工程（英文）》 2023年 第29卷 第10期   页码 83-94 doi: 10.1016/j.eng.2023.05.006

摘要：

全厚皮肤移植对于重建皮肤屏障、促进伤口愈合至关重要，充足的氧气供给与皮肤移植的成功密切相关。然而，全厚皮肤的氧气递送受限于皮肤对氧气的低渗透性。在本篇文章中，构建了产氧缝合线用于促进全厚皮肤的氧气渗透。在皮肤模型的15 mm厚度处，产氧缝合线递送的氧气量是局部气态氧疗的100倍以上。在极端乏氧（< 0.5% O2，v/v）环境下，产氧缝合线可以促进内皮细胞增殖。通过小鼠自体皮瓣移植实验发现，产氧缝合线帮助恢复血液再灌注、促进移植皮肤的存活。产氧缝合线有望在临床中被使用，促进全厚皮肤移植的成功。

关键词： 伤口     皮肤移植     产氧缝合线     全层氧气递送    

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The effects of interfacial strength on fractured microcapsule

Luthfi Muhammad MAULUDIN, Chahmi OUCIF

《结构与土木工程前沿（英文）》 2019年 第13卷 第2期   页码 353-363 doi: 10.1007/s11709-018-0469-3

摘要： The effects of interfacial strength on fractured microcapsule are investigated numerically. The interaction between crack and microcapsule embedded in mortar matrix is modeled based on cohesive approach. The microcapsules are modelled with variation of core-shell thickness ratio and potential cracks are represented by pre-inserted cohesive elements along the element boundaries of the mortar matrix, microcapsules core, microcapsule shell, and at the interfaces between these phases. Special attention is given to the effects of cohesive fracture on the microcapsule interface, namely fracture strength, on the load carrying capacity and fracture probability of the microcapsule. The effect of fracture properties on microcapsule is found to be significant factor on the load carrying capacity and crack propagation characteristics. Regardless of core-shell thickness ratio of microcapsule, the load carrying capacity of self-healing material under tension increases as interfacial strength of microcapsule shell increases. In addition, given the fixed fracture strength of the interface of microcapsule shell, the higher the ratio core-shell thickness, the higher the probability of microcapsules being fractured.

关键词： interfacial strength     cohesive elements     microcapsule     core-shell thickness ratio     fracture properties    

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Numerical simulation of liquid falling film on horizontal circular tubes

Fengdan SUN, Songlin XU, Yongchuan GAO

《化学科学与工程前沿（英文）》 2012年 第6卷 第3期   页码 322-328 doi: 10.1007/s11705-012-1296-z

摘要： The objective of this study is to investigate numerically the flow characteristics of falling film on horizontal circular tubes. Numerical simulations are performed using FLUENT for 2D configurations with one and two cylinders. The volume of fluid method is used to track the motion of liquid falling film and the gas-liquid interface. The effect of flow characteristics on heat and transfer coefficient may be remarkable, although it has been neglected in previous studies. The velocity distribution and the film thickness characteristics on the top tube, some special flow characteristics on the bottom tube, intertube flow modes and effect of liquid feeder height on flow characteristics have been studied. Our simulations indicate that 1) the velocity distributions of the upper and lower parts of the tube are not strictly symmetric and non-uniform, 2) the film thickness depends on flow rate and angular distributions, 3) the flow characteristics of the top tube are different from those of the bottom tube, 4) three principal and two intermediate transition modes are distinguished, and 5) the liquid feed height plays an important role on the formation of falling film. The numerical results are in a good agreement with the theoretical values by the Nusselt model and the reported results.

关键词： falling film     horizontal tube     flow characteristics     film thickness     liquid feeder height    

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标题 作者 时间 类型 操作

Genome-wide association study of the backfat thickness trait in two pig populations

Dandan ZHU,Xiaolei LIU,Rothschild MAX,Zhiwu ZHANG,Shuhong ZHAO,Bin FAN

期刊论文

Effects of sheet thickness and material on the mechanical properties of flat clinched joint

Chao CHEN, Huiyang ZHANG, Shengdun ZHAO, Xiaoqiang REN

期刊论文

Lamellar thickness transition of melt-crystallized polybuten-1 tetragonal phase: configurational change

Motoi YAMASHITA

期刊论文

Modeling of the minimum cutting thickness in micro cutting with consideration of the friction around

Tianfeng ZHOU, Ying WANG, Benshuai RUAN, Zhiqiang LIANG, Xibin WANG

期刊论文

Numerical simulation of compaction parameters for sand-filled embankment using large thickness sand filling

Wentao WANG, Chongzhi TU, Rong LUO

期刊论文

Determining the optimum economic insulation thickness of double pipes buried in the soil for district

Fating LI, Pengfei JIE, Zhou FANG, Zhimei WEN

期刊论文

Time of flight improved thermally grown oxide thickness measurement with terahertz spectroscopy

期刊论文

Optimizing environmental insulation thickness of buildings with CHP-based district heating system based

Yumei ZHANG, Pengfei JIE, Chunhua LIU, Jing LI

期刊论文

The ITZ microstructure, thickness, porosity and its relation with compressive and flexural strength of

期刊论文

Eddy current measurement of the thickness of top Cu film of the multilayer interconnects in the integrated

Zilian QU,Yonggang MENG,Qian ZHAO

期刊论文

numerical studies on concrete encased trapezoidally web profiled cold formed steel beams by varying depth-thickness

Divahar RAVI, Aravind Raj PONSUBBIAH, Sangeetha Sreekumar PRABHA, Joanna Philip SARATHA

期刊论文

Elastoplastic frictional contact problem study on interference fits of compressor

ZHANG Hongwu, WU Changhua, LIAO Aihua

期刊论文

产氧缝合线介导的氧气全层渗透用于促进移植皮肤的存活

宰文静, 袁雨浓, 康琳, 许加龙, 胡一桥, 康立峰, 吴锦慧

期刊论文

The effects of interfacial strength on fractured microcapsule

Luthfi Muhammad MAULUDIN, Chahmi OUCIF

期刊论文

Numerical simulation of liquid falling film on horizontal circular tubes

Fengdan SUN, Songlin XU, Yongchuan GAO

期刊论文