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Caveolin proteins: a molecular insight into disease
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《医学前沿（英文）》 2016年 第10卷 第4期 页码 397-404 doi: 10.1007/s11684-016-0483-6
Caveolae are a kind of specific cystic structures of lipid rafts in the cytoplasmic membrane and are rich in cholesterol and sphingolipids. In recent years, many researchers have found that both caveolins and caveolae play a role in the development of various human diseases, including coronary heart disease, hypertension, and nervous system disorders. The specific mechanisms by which caveolins induce diseases have been a topic of interest. However, a number of detailed molecular mechanisms remain poorly understood. This article focuses on the relationship between caveolin proteins and human diseases and reviews the molecular mechanisms of caveolins in disease networks.
关键词： caveolin caveolae microRNA disease signaling pathway heart tumor
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