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Stem cell niches and endogenous electric fields in tissue repair

null

《医学前沿(英文)》 2011年 第5卷 第1期   页码 40-44 doi: 10.1007/s11684-011-0108-z

摘要:

Adult stem cells are responsible for homeostasis and repair of many tissues. Endogenous adult stem cells reside in certain regions of organs, known as the stem cell niche, which is recognized to have an important role in regulating tissue maintenance and repair. In wound healing and tissue repair, stem cells are mobilized and recruited to the site of wound, and participate in the repair process. Many regulatory factors are involved in the stem cell-based repair process, including stem cell niches and endogenous wound electric fields, which are present at wound tissues and proved to be important in guiding wound healing. Here we briefly review the role of stem cell niches and endogenous electric fields in tissue repair, and hypothesize that endogenous electric fields become part of stem cell niche in the wound site.

关键词: stem cell     stem cell niche     electric field     tissue repair    

Immune response triggered by the ablation of hepatocellular carcinoma with nanosecond pulsed electric

Jianpeng Liu, Xinhua Chen, Shusen Zheng

《医学前沿(英文)》 2021年 第15卷 第2期   页码 170-177 doi: 10.1007/s11684-020-0747-z

摘要: Nanosecond pulsed electric field (nsPEF) is a novel, nonthermal, and minimally invasive modality that can ablate solid tumors by inducing apoptosis. Recent animal experiments show that nsPEF can induce the immunogenic cell death of hepatocellular carcinoma (HCC) and stimulate the host’s immune response to kill residual tumor cells and decrease distant metastatic tumors. nsPEF-induced immunity is of great clinical importance because the nonthermal ablation may enhance the immune memory, which can prevent HCC recurrence and metastasis. This review summarized the most advanced research on the effect of nsPEF. The possible mechanisms of how locoregional nsPEF ablation enhances the systemic anticancer immune responses were illustrated. nsPEF stimulates the host immune system to boost stimulation and prevail suppression. Also, nsPEF increases the dendritic cell loading and inhibits the regulatory responses, thereby improving immune stimulation and limiting immunosuppression in HCC-bearing hosts. Therefore, nsPEF has excellent potential for HCC treatment.

关键词: nanosecond pulsed electric fields (nsPEF)     hepatocellular carcinoma (HCC)     immune response     recurrence     metastasis    

Analysis of mobilization of inorganic ions in soil by electrokinetic remediation

Xiaojing LI, Lige WANG, Xueming SUN, Yuansheng CONG

《结构与土木工程前沿(英文)》 2019年 第13卷 第6期   页码 1463-1473 doi: 10.1007/s11709-019-0569-8

摘要: Saline soil has imposed a serious threat on many expressway engineering and agricultural areas. This paper describes the performance of saline soil treatment using electrokinetic remediation technology. Comparison study involving sample soil and soil is carried out. Two different electric fields, i.e., uniform and non-uniform are utilized to promote the migration of inorganic ions contained in the soil toward the electrode area. The effects of different electric field types and potential gradient ion migration rate in soil are investigated. The test result reveals that a uniform electric field of a constant potential gradient of 1 V/cm drives the Cl through the sample soil at a rate of 1.36 cm/h. Moreover, larger potential gradients could make ions migrate faster, but more electrical energy is consumed in such a way. Compared with uniform electric field, the non-uniform process maintains the soil pH values more effectively and consumes less electrical energy. A desirable result of removing Na in soil is expected using electrokinetic remediation technology under four-times scaling up of soil volume.

关键词: electromigration     electric fields     saline soil     soil-remediation    

Simulation of heterogeneous two-phase media using random fields and level sets

George STEFANOU

《结构与土木工程前沿(英文)》 2015年 第9卷 第2期   页码 114-120 doi: 10.1007/s11709-014-0267-5

摘要: The accurate and efficient simulation of random heterogeneous media is important in the framework of modeling and design of complex materials across multiple length scales. It is usually assumed that the morphology of a random microstructure can be described as a non-Gaussian random field that is completely defined by its multivariate distribution. A particular kind of non-Gaussian random fields with great practical importance is that of translation fields resulting from a simple memory-less transformation of an underlying Gaussian field with known second-order statistics. This paper provides a critical examination of existing random field models of heterogeneous two-phase media with emphasis on level-cut random fields which are a special case of translation fields. The case of random level sets, often used to represent the geometry of physical systems, is also examined. Two numerical examples are provided to illustrate the basic features of the different approaches.

关键词: microstructure     random fields     level sets     shape recovery     two-phase media    

NITROGEN USE AND MANAGEMENT IN ORCHARDS AND VEGETABLE FIELDS IN CHINA: CHALLENGES AND SOLUTIONS

《农业科学与工程前沿(英文)》 2022年 第9卷 第3期   页码 386-395 doi: 10.15302/J-FASE-2022443

摘要:

● Excessive application of N fertilizers in orchards and vegetable fields (OVFs) in China is particularly common.

关键词: nitrogen fate     nitrogen fertilizer     orchards     vegetable fields    

Advanced biomass materials: progress in the applications for energy, environmental, and emerging fields

《化学科学与工程前沿(英文)》 2023年 第17卷 第7期   页码 795-797 doi: 10.1007/s11705-023-2336-6

摘要: Advanced biomass materials: progress in the applications for energy, environmental, and emerging fields

关键词: progress applications energy     fields    

Engineering Fronts in fields of Energy and Electrical Science and Technologies in the report of

《能源前沿(英文)》 2023年 第17卷 第1期   页码 5-8 doi: 10.1007/s11708-023-0868-6

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The perturbed magnetic fields caused by mechanical stress

QIN Fei, YAN Dong-mei

《机械工程前沿(英文)》 2006年 第1卷 第2期   页码 151-156 doi: 10.1007/s11465-006-0015-1

摘要: In the framework of the linearized magnetoelastic theory, the perturbed magnetic fields caused by mechanical stress and deformation were investigated theoretically. Governing equations and boundary conditions to determine the perturbed fields were derived. The effect of mechanical deformation on the magnetic fields was taken into account by coupling structural displacement into the perturbed magnetic field continuous conditions on the boundary of the structure. As an example, the perturbed field of a half-plane magnetized structure caused by a point force was calculated by the Fourier transform method. The results show that the calculated magnetic intensity component normal to the boundary of the structure reaches its maximum at the point force acted while the component tangent to the boundary inverses its direction sharply. The magnetic induction of the perturbed field is proportional to the applied force. Magnitude analysis proved that since the applied magnetic field has a relative weak intensity such as the Earth s magnetic field, influence of the magnetic field on deformation of the structure can be neglected.

Characterization of random stress fields obtained from polycrystalline aggregate calculations using multi-scale

Bruno SUDRET,Hung Xuan DANG,Marc BERVEILLER,Asmahana ZEGHADI,Thierry YALAMAS

《结构与土木工程前沿(英文)》 2015年 第9卷 第2期   页码 121-140 doi: 10.1007/s11709-015-0290-1

摘要: The spatial variability of stress fields resulting from polycrystalline aggregate calculations involving random grain geometry and crystal orientations is investigated. A periodogram-based method is proposed to identify the properties of homogeneous Gaussian random fields (power spectral density and related covariance structure). Based on a set of finite element polycrystalline aggregate calculations the properties of the maximal principal stress field are identified. Two cases are considered, using either a fixed or random grain geometry. The stability of the method w.r.t the number of samples and the load level (up to 3.5% macroscopic deformation) is investigated.

关键词: polycrystalline aggregates     crystal plasticity     random fields     spatial variability     correlation structure    

Extrapolation reconstruction of wind pressure fields on the claddings of high-rise buildings

Yehua SUN, Guquan SONG, Hui LV

《结构与土木工程前沿(英文)》 2019年 第13卷 第3期   页码 653-666 doi: 10.1007/s11709-018-0503-5

摘要: Recent research about reconstruction methods mainly used the interpolation reconstruction of the fluctuating wind pressure field on the surface. However, to investigate wind pressure at the edge of the building, the work presented in this paper focuses on the extrapolation reconstruction of wind pressure fields. Here, we propose an improved proper orthogonal decomposition (POD) and Kriging method with a von Kármán correlation function to resolve this issue. The studies show that it works well for not only interpolation reconstruction but also extrapolation reconstruction. The proposed method does require determination of the Hurst exponent and other parameters analysed from the original data. Hence, the fluctuating wind fields have been characterized by the von Kármán correlation function, as an a priori function. Compared with the cubic spline method and different variogram, preliminary results suggest less time consumption and high efficiency in extrapolation reconstruction at the edge.

关键词: extrapolation reconstruction     proper orthogonal decomposition     Kriging method     von Kármán function     Hurst exponent     rescaled range analysis    

Techno-economic analysis of the adoption of electric vehicles

Donald KENNEDY, Simon P. PHILBIN

《工程管理前沿(英文)》 2019年 第6卷 第4期   页码 538-550 doi: 10.1007/s42524-019-0048-x

摘要: Significant advances in battery technology are creating a viable marketspace for battery powered passenger vehicles. Climate change and concerns over reliable supplies of hydrocarbons are aiding in the focus on electric vehicles. Consumers can be influenced by marketing and emotion resulting in behaviors that may not be in line with their stated objectives. Although sales of electric vehicles are accelerating, it may not be clear that purchasing an electric vehicle is advantageous from an economic or environmental perspective. A techno- economic analysis of electric vehicles comparing them against hybrids, gasoline and diesel vehicles is presented. The results show that the complexity of electrical power supply, infrastructure requirements and full life cycle concerns show that electric vehicles have a place in the future but that ongoing improvements will be required for them to be clearly the best choice for a given situation.

关键词: BEV     battery powered electric vehicle     environmental impact of electric vehicles     techno-economic analysis     gasoline versus electric powered cars     diesel versus electric cars     consumer behaviour    

SOIL CARBON CHECK: A TOOL FOR MONITORING AND GUIDING SOIL CARBON SEQUESTRATION IN FARMER FIELDS

《农业科学与工程前沿(英文)》 2023年 第10卷 第2期   页码 248-261 doi: 10.15302/J-FASE-2023499

摘要:

● Establishment of a rapid tool for monitoring soil carbon sequestration in farmer fields.

关键词: 4 per 1000 initiative     carbon sequestration     climate action     farmer fields     SDG13     soil organic carbon     soil testing    

Recent progress in electric-field assisted combustion: a brief review

《能源前沿(英文)》 2022年 第16卷 第6期   页码 883-899 doi: 10.1007/s11708-021-0770-z

摘要: The control of combustion is a hot and classical topic. Among the combustion technologies, electric-field assisted combustion is an advanced techno-logy that enjoys major advantages such as fast response and low power consumption compared with thermal power. However, its fundamental principle and impacts on the flames are complicated due to the coupling between physics, chemistry, and electromagnetics. In the last two decades, tremendous efforts have been made to understand electric-field assisted combustion. New observations have been reported based on different combustion systems and improved diagnostics. The main impacts, including flame stabilization, emission reduction, and flame propagation, have been revealed by both simulative and experimental studies. These findings significantly facilitate the application of electric-field assisted combustion. This brief review is intended to provide a comprehensive overview of the recent progress of this combustion technology and further point out research opportunities worth investigation.

关键词: electric field     combustion     flame stabilization     emission reduction     flame propagation    

Design and characteristics of electric supercharger for diesel engine acceleration by additional rapid

YAO Chun-de, ZHOU Hong-xiu

《机械工程前沿(英文)》 2006年 第1卷 第4期   页码 409-412 doi: 10.1007/s11465-006-0048-5

摘要: The ES (electric supercharger) driven by a high-speed brushless motor was developed to solve the problem of smoke caused by the turbocharger s sluggish response during acceleration. Its rotation speed was from 6 000 r/min to 24 000 r/min, and the maximum flux was 0.1 kg/s. The structural design of the electric supercharger is novel, which makes it easier to set the lubricating installation and to assemble. The velocity distribution at the outlet of the electric supercharger is determined by hot-wire anemometry under various rotation speeds in steady state. Furthermore, the trends of the flux and charge rate with various speeds were analyzed. In addition, the transient response was detected from the motor setup to smooth running within 10 s, 15 s, 20 s and 25 s respectively, and the characteristic of the transient flux is under pilot study. Research results indicate that the electric supercharger can respond rapidly with the great flux, and it is independent of the operating conditions of a diesel engine. Therefore, it is a feasible way to reduce smoke emission and improve the acceleration performance.

关键词: acceleration     velocity distribution     high-speed brushless     turbocharger     electric supercharger    

Lightweight design of an electric bus body structure with analytical target cascading

《机械工程前沿(英文)》 2023年 第18卷 第1期 doi: 10.1007/s11465-022-0718-y

摘要: Lightweight designs of new-energy vehicles can reduce energy consumption, thereby improving driving mileage. In this study, a lightweight design of a newly developed multi-material electric bus body structure is examined in combination with analytical target cascading (ATC). By proposing an ATC-based two-level optimization strategy, the original lightweight design problem is decomposed into the system level and three subsystem levels. The system-level optimization model is related to mass minimization with all the structural modal frequency constraints, while each subsystem-level optimization model is related to the sub-structural performance objective with sub-structure mass constraints. To enhance the interaction between two-level systems, each subsystem-level objective is reformulated as a penalty-based function coordinated with the system-level objective. To guarantee the accuracy of the model-based analysis, a finite element model is validated through experimental modal test. A sequential quadratic programming algorithm is used to address the defined optimization problem for effective convergence. Compared with the initial design, the total mass is reduced by 49 kg, and the torsional stiffness is increased by 17.5%. In addition, the obtained design is also validated through strength analysis.

关键词: electric vehicle     body in white (BIW)     lightweight     analytical target cascading (ATC)    

标题 作者 时间 类型 操作

Stem cell niches and endogenous electric fields in tissue repair

null

期刊论文

Immune response triggered by the ablation of hepatocellular carcinoma with nanosecond pulsed electric

Jianpeng Liu, Xinhua Chen, Shusen Zheng

期刊论文

Analysis of mobilization of inorganic ions in soil by electrokinetic remediation

Xiaojing LI, Lige WANG, Xueming SUN, Yuansheng CONG

期刊论文

Simulation of heterogeneous two-phase media using random fields and level sets

George STEFANOU

期刊论文

NITROGEN USE AND MANAGEMENT IN ORCHARDS AND VEGETABLE FIELDS IN CHINA: CHALLENGES AND SOLUTIONS

期刊论文

Advanced biomass materials: progress in the applications for energy, environmental, and emerging fields

期刊论文

Engineering Fronts in fields of Energy and Electrical Science and Technologies in the report of

期刊论文

The perturbed magnetic fields caused by mechanical stress

QIN Fei, YAN Dong-mei

期刊论文

Characterization of random stress fields obtained from polycrystalline aggregate calculations using multi-scale

Bruno SUDRET,Hung Xuan DANG,Marc BERVEILLER,Asmahana ZEGHADI,Thierry YALAMAS

期刊论文

Extrapolation reconstruction of wind pressure fields on the claddings of high-rise buildings

Yehua SUN, Guquan SONG, Hui LV

期刊论文

Techno-economic analysis of the adoption of electric vehicles

Donald KENNEDY, Simon P. PHILBIN

期刊论文

SOIL CARBON CHECK: A TOOL FOR MONITORING AND GUIDING SOIL CARBON SEQUESTRATION IN FARMER FIELDS

期刊论文

Recent progress in electric-field assisted combustion: a brief review

期刊论文

Design and characteristics of electric supercharger for diesel engine acceleration by additional rapid

YAO Chun-de, ZHOU Hong-xiu

期刊论文

Lightweight design of an electric bus body structure with analytical target cascading

期刊论文