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Progress in NMR-based metabolomics of
Qifang PAN,Jingya ZHAO,Yuliang WANG,Kexuan TANG
《农业科学与工程前沿(英文)》 2015年 第2卷 第3期 页码 195-204 doi: 10.15302/J-FASE-2015063
关键词: Catharanthus roseus monoterpenoid indole alkaloids NMR metabolomics
Yurong ZHANG, Shengxuan XU, Yanhong GAO, Jie GUO, Yinghui CAO, Junzhi ZHANG
《结构与土木工程前沿(英文)》 2020年 第14卷 第6期 页码 1509-1519 doi: 10.1007/s11709-020-0681-9
关键词: permeability microstructure NMR MIP X-CT
Solid-state NMR for metal-containing zeolites: From active sites to reaction mechanism
Xingling Zhao, Jun Xu, Feng Deng
《化学科学与工程前沿(英文)》 2020年 第14卷 第2期 页码 159-187 doi: 10.1007/s11705-019-1885-1
关键词: metal-containing zeolites solid-state NMR active site host-guest interaction reaction mechanism
Siming Chen, Yue Wu, Geoffrey W. Stevens, Guoping Hu, Wenshou Sun, Kathryn A. Mumford
《化学科学与工程前沿(英文)》 2020年 第14卷 第3期 页码 415-424 doi: 10.1007/s11705-019-1882-4
A review of measurement methods for peracetic acid (PAA)
Chen Cheng, Haodong Li, Jinling Wang, Hualin Wang, Xuejing Yang
《环境科学与工程前沿(英文)》 2020年 第14卷 第5期 doi: 10.1007/s11783-020-1266-5
关键词: Peroxyacetic acid Measurement methods Titration Colorimetric Chromatography NMR
Metabolomics in human type 2 diabetes research
null
《医学前沿(英文)》 2013年 第7卷 第1期 页码 4-13 doi: 10.1007/s11684-013-0248-4
The high prevalence of diabetes and diabetic complications has caused a huge burden on the modern society. Although scientific advances have led to effective strategies for preventing and treating diabetes over the past several decades, little progress has been made toward curing the disease or even getting it under control, from a public health and overall societal standpoint. There is still a lack of reliable biomarkers indicative of metabolic alterations associated with diabetes and different drug responses, highlighting the need for the development of early diagnostic and prognostic markers for diabetes and diabetic complications. The emergence of metabolomics has allowed researchers to systemically measure the small molecule metabolites, which are sensitive to the changes of both environmental and genetic factors and therefore, could be regarded as the link between genotypes and phenotypes. During the last decade, the progression made in metabolomics has provided insightful information on disease development and disease onset prediction. Recent studies using metabolomics approach coupled with statistical tools to predict incident diabetes revealed a number of metabolites that are significantly altered, including branched-chain and aromatic amino acids, such as isoleucine, leucine, valine, tyrosine and phenylalanine, as diagnostic or highly-significant predictors of future diabetes. This review summarizes the current findings of metabolomic studies in human investigations with the most common form of diabetes, type 2 diabetes.
关键词: metabolomics type 2 diabetes metabolic pathway mass spectrometry nuclear magnetic resonance (NMR)
G-quadruplex formation of oligonucleotides containing ALS and FTD related GGGGCC repeat
Jasna Brčić,Janez Plavec
《化学科学与工程前沿(英文)》 2016年 第10卷 第2期 页码 222-237 doi: 10.1007/s11705-016-1556-4
于德泉
《中国工程科学》 1999年 第1卷 第2期 页码 87-90
文章展望了从天然产物中创制新药的发展趋势。单味中草药有效成分的研究重点将转向瞄准质控的中药复方化学成分研究。进入21世纪,中国天然药物研究要在国际上占有重要位置,突破口便是中药复方现代化,其关键之一便是化学(有效)成分研究。从中草药中发现有效成分或先导物必须采用化学成分与生物活性研究融为一体的机制,采用高通量筛选,目标就是寻找有效成分或先导物进而创制新药。长短结合,正确处理知识创新和新药开发的关系。知识创新须体现在创制新药的应用基础研究中,是产生巨大效益的理论基础;短程开发是知识累积水平的体现,是科研经费的必要补充和保证。改革传统天然产物化学研究模式,实施以当代最先进大型谱仪为先导的天然产物研究战略。
Solvability and thermal response of cellulose with different crystal configurations
Qian CHEN, Kai ZHENG, Qingtao FAN, Kun WANG, Haiyan YANG, Jianxin JIANG, Shijie LIU
《工程管理前沿(英文)》 2019年 第6卷 第1期 页码 62-69 doi: 10.1007/s42524-019-0001-z
Cellulose is a biodegradable and renewable natural material that it is naturally resistant to breaking and modification. Moreover, the crystalline structure of cellulose is a major factor restricting its industrial utilization. In this study, cellulose polymorphs were prepared from natural cellulose, and their solvability and thermal response were investigated. Using liquid- and solid-state NMR signals, the distinct types and dissolving states of cellulose polymorphs were identified. The thermal behavior of the polymorphic forms of cellulose-d was also evaluated, and cellulose II exhibited the poorest thermal stability and a unique exothermic reaction.
关键词: cellulose crystal structure thermal response XRD CP/MAS 13C NMR
Annett SCHROETER, Tanja ENGELBRECHT, Reinhard H. H. NEUBERT
《化学科学与工程前沿(英文)》 2013年 第7卷 第1期 页码 29-36 doi: 10.1007/s11705-013-1302-0
关键词: nano-structure of the stratum corneum ceramide penetration enhancer model membrane neutron diffraction 2H NMR spectroscopy
Jianzhang Sun, Baoyu Gao, Yuanxia Luo, Moxi Xue, Xing Xu, Qinyan Yue, Yan Wang
《环境科学与工程前沿(英文)》 2018年 第12卷 第3期 doi: 10.1007/s11783-018-1029-8
关键词: Algal Extraction Enteromorpha polysaccharide 1H-13C nuclear magnetic resonance (NMR) Fourier transform infrared (FTIR) X-ray photoelectron spectroscopy (XPS) Coagulation mechanism.
标题 作者 时间 类型 操作
chloride diffusion coefficient and microstructure parameters in concrete: A comparative analysis using NMR
Yurong ZHANG, Shengxuan XU, Yanhong GAO, Jie GUO, Yinghui CAO, Junzhi ZHANG
期刊论文
Solid-state NMR for metal-containing zeolites: From active sites to reaction mechanism
Xingling Zhao, Jun Xu, Feng Deng
期刊论文
Precipitation study of CO
Siming Chen, Yue Wu, Geoffrey W. Stevens, Guoping Hu, Wenshou Sun, Kathryn A. Mumford
期刊论文
A review of measurement methods for peracetic acid (PAA)
Chen Cheng, Haodong Li, Jinling Wang, Hualin Wang, Xuejing Yang
期刊论文
G-quadruplex formation of oligonucleotides containing ALS and FTD related GGGGCC repeat
Jasna Brčić,Janez Plavec
期刊论文
Solvability and thermal response of cellulose with different crystal configurations
Qian CHEN, Kai ZHENG, Qingtao FAN, Kun WANG, Haiyan YANG, Jianxin JIANG, Shijie LIU
期刊论文
Influence of short chain ceramides and lipophilic penetration enhancers on the nano-structure of stratum corneum model membranes studied using neutron diffraction
Annett SCHROETER, Tanja ENGELBRECHT, Reinhard H. H. NEUBERT
期刊论文