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基于S3C2410的GPRS数据终端的设计

孙学用

《中国工程科学》 2007年 第9卷 第12期   页码 94-96

摘要: 提出了以S3C2410处理器为核心,以SIM100-E为GPRS通信模块,构建了一套嵌入式Internet数据终端的方案,对其硬件构成及工作流程进行了讨论,描述了其软件层次结构,并详细讲解了基于该平台的

关键词: GPRS;嵌入式Internet;S3C2410;SIM100-E    

Fabrication of MIL-100(Fe)@SiO

Yinlong Hu,Shuang Zheng,Fumin Zhang

《化学科学与工程前沿(英文)》 2016年 第10卷 第4期   页码 534-541 doi: 10.1007/s11705-016-1596-9

摘要: Heterogeneous catalysts with convenient recyclability and reusability are vitally important to reduce the cost of catalysts as well as to avoid complex separation and recovery operations. In this regard, magnetic MIL-100(Fe)@SiO @Fe O microspheres with a novel core-shell structure were fabricated by the self-assembly of a metal-organic MIL-100(Fe) framework around pre-synthesized magnetic SiO @Fe O particles under relatively mild and environmentally benign conditions. The catalytic activity of the MIL-100(Fe)@SiO @Fe O catalyst was tested for the liquid-phase acetalization of benzaldehyde and glycol. The MIL-100(Fe)@SiO @Fe O catalyst has a significant amount of accessible Lewis acid sites and therefore exhibited good acetalization catalytic activity. Moreover, due to its superparamagnetism properties, the heterogeneous MIL-100(Fe)@SiO @Fe O catalyst can be easily isolated from the reaction system within a few seconds by simply using an external magnet. The catalyst could then be reused at least eight times without significant loss in catalytic efficiency.

关键词: metal-organic frameworks     heterogeneous catalysis     magnetically recoverable catalysts     core-shell structure     acetalization    

Analysis of 100 consecutive cases of resectable pancreatic neuroendocrine neoplasms: clinicopathological

null

《医学前沿(英文)》 2016年 第10卷 第4期   页码 444-450 doi: 10.1007/s11684-016-0471-x

摘要:

The incidence rate of pancreatic neuroendocrine neoplasms (pNENs) has increased rapidly in recent years. However, the clinicopathological characteristics of pNENs are poorly understood. Medical records of patients who underwent surgery and were confirmed as pNENs by pathological examination from January 2003 to February 2015 in Qilu Hospital were reviewed retrospectively. A total of 100 patients, 36 males and 64 females, were included with a mean operation age of 46.26±13.41 years. Among the 100 cases, 76 had insulinomas and 24 had non-functional pNENs. Tumor size ranged from 0.5 cm to 9 cm, and the mean size was 2.20±1.40 cm. The percentages of TNM stages I, II, III, and IV tumors were 89.0%, 8.0%, 0.0%, and 3.0%, respectively. Based on the WHO classification, pNENs were classified into three grades: G1, G2, and G3. G1, G2, and G3 tumors were confirmed in 72.9%, 23.7%, and 3.4% patients, respectively. The positive rates of CgA and Syn immunohistochemical staining were 94.5% (69/73) and 100% (74/74), respectively. Compared with insulinoma, non-functional pNENs have larger tumor sizes, more advanced TNM staging, a higher Ki-67 index, and a higher rate of liver metastasis (P<0.05). In conclusion, pNENs are heterogeneous tumors with varying clinical manifestations, diverse tumor biological characteristics, and different prognoses. Non-functional pNENs present a more aggressive behavioral model and have poorer prognosis than functional pNENs.

关键词: pancreatic neuroendocrine neoplasms     clinicopathological characteristic     Ki-67     liver metastasis     outcomes    

Regulatory mechanism and functional analysis of

null

《医学前沿(英文)》 2017年 第11卷 第1期   页码 87-96 doi: 10.1007/s11684-016-0469-4

摘要:

S100A9, a calcium-binding protein, participates in the inflammatory process and development of various tumors, thus attracting much attention in the field of cancer biology. This study aimed to investigate the regulatory mechanism of and its function involvement in APL. We used real-time quantitative PCR to determine whether PML/RARα affects the expression of in NB4 and PR9 cells upon ATRA treatment. ChIP-based PCR and dual-luciferase reporter assay system were used to detect how PML/RARα and PU.1 regulate promoter activity. CCK-8 assay and flow cytometry were employed to observe the viability and apoptosis of NB4 cells when was overexpressed. Results showed that was an ATRA-responsive gene, and PML/RARα was necessary for the ATRA-induced expression of in APL cells. In addition, PU.1 could bind to the promoter of , especially when treated with ATRA in NB4 cells, and promote its activity. More importantly, overexpression of induced the apoptosis of NB4 cells and inhibited cell growth. Collectively, our data indicated that PML/RARα and PU.1 were necessary for the ATRA-induced expression of in APL cells. Furthermore, promoted apoptosis in APL cells and affected cell growth.

关键词: S100A9 S100A9     PU.1     PML/RARα     ATRA     APL    

quality of care for patients with type 2 diabetes in China: findings from the Shanghai Integration Model (SIM

《医学前沿(英文)》 2022年 第16卷 第1期   页码 126-138 doi: 10.1007/s11684-021-0897-7

摘要: This cross-sectional study aimed to investigate the quality of care of diabetes in Shanghai, China. A total of 173 235 patients with type 2 diabetes in 2017 were included in the analysis. Profiles of risk factors and intermediate outcomes were determined. The patients had a mean age of 66.43±8.12 (standard deviation (SD)) years and a mean diabetes duration of 7.95±5.53 (SD) years. The percentage of patients who achieved the target level for HbA1c (<7.0%) was 48.6%. Patients who achieved the target levels for blood pressure (BP)<130/80 mmHg and low-density lipoprotein-cholesterol (LDL-c)<2.6 mmol/L reached 17.5% and 34.0%, respectively. A total of 3.8% achieved all three target levels, and the value increased to 6.8% with an adaptation of the BP target level (<140/90 mmHg) for those over 65 years. Multivariable analysis identified the factors associated with a great likelihood of achieving all three target levels: male, young age, short diabetes duration, low body mass index, macrovascular complications, no microvascular complications, prescribed with lipid-lowering medication, and no prescription of antihypertensive medication. In conclusion, nearly 50% and one-third of the patients with diabetes met the target levels for HbA1c and LDL-c, respectively, with a low percentage achieving the BP target level. The percentage of patients who achieved all three target levels needs significant improvement.

关键词: type 2 diabetes     quality of care     macrovascular complication     microvascular complication     treatment pattern     epidemiology    

Development of temperature-robust damage factor based on sensor fusion for a wind turbine structure

Jong-Woong PARK,Sung-Han SIM,Jin-Hak YI,Hyung-Jo JUNG

《结构与土木工程前沿(英文)》 2015年 第9卷 第1期   页码 42-47 doi: 10.1007/s11709-014-0285-3

摘要: Wind power systems have gained much attention due to the relatively high reliability, maturity in technology and cost competitiveness compared to other renewable alternatives. Advances have been made to increase the power efficiency of the wind turbines while less attention has been focused on structural integrity assessment of the structural systems. Vibration-based damage detection has widely been researched to identify damages on a structure based on change in dynamic characteristics. Widely spread methods are natural frequency-based, mode shape-based, and curvature mode shape-based methods. The natural frequency-based methods are convenient but vulnerable to environmental temperature variation which degrades damage detection capability; mode shapes are less influenced by temperature variation and able to locate damage but requires extensive sensor instrumentation which is costly and vulnerable to signal noises. This study proposes novelty of damage factor based on sensor fusion to exclude effect of temperature variation. The combined use of an accelerometer and an inclinometer was considered and damage factor was defined as a change in relationship between those two measurements. The advantages of the proposed method are: 1) requirement of small number of sensor, 2) robustness to change in temperature and signal noise and 3) ability to roughly locate damage. Validation of the proposed method is carried out through numerical simulation on a simplified 5 MW wind turbine model.

关键词: sensor fusion     damage detection     structural health monitoring    

Lignin-based electrospun nanofiber membrane decorated with photo-Fenton Ag@MIF-100(Fe) heterojunctions

《化学科学与工程前沿(英文)》 2023年 第17卷 第7期   页码 930-941 doi: 10.1007/s11705-023-2309-9

摘要: Membrane technology for wastewater remediation has aroused wide interest owing to its unique properties and potential applications. However, it remains challenging to explore green, efficient and robust membrane material and technique for complex wastewater treatment. Herein, we proposed using a simple electrospinning and in situ seeding method to fabricate a lignin-based electrospun nanofiber membrane (LENM) decorated with photo-Fenton Ag@MIL-100(Fe) heterojunctions for efficient separation of oil/water emulsions and degradation of organic dye. Thanks to the embedded lignin in LENM, an ultrahigh MIL-100(Fe) loading (53 wt %) with good wettability and high porosity was obtained. As a result, the hybrid Ag@MIL-100(Fe)/LENM exhibited excellent oil/water emulsions separation efficiency (more than 97%) without a compromise of water flux. Moreover, the hybrid membrane showed an excellent dye removal with degradation of 99% methylene blue within 30 min under illumination, which is attributed to a synergy of dye adsorption/enrichment and photo-Fenton catalytic degradation from Ag@MIL-100(Fe). Therefore, the lignin-based photo-Fenton hybrid membrane can lay the foundation for the preparation and application of green, sustainable and versatile membrane materials and technologies for efficient complex wastewater remediation.

关键词: lignin     electrospinning     heterojunctions     photo-Fenton catalysis     wastewater remediation    

Annexin A2-S100A10 heterotetramer is upregulated by PML/RARα fusion protein and promotes plasminogen-dependent

null

《医学前沿(英文)》 2017年 第11卷 第3期   页码 410-422 doi: 10.1007/s11684-017-0527-6

摘要:

Aberrant expression of annexin A2-S100A10 heterotetramer (AIIt) associated with PML/RARα fusion protein causes lethal hyperfibrinolysis in acute promyelocytic leukemia (APL), but the mechanism is unclear. To facilitate the investigation of regulatory association between ANXA2 and promyelocytic leukemia/retinoic acid receptor a (PML/RARα) fusion protein, this work was performed to determine the transcription start site of ANXA2 promoter with rapid amplification of 5′-cDNA ends analysis. Zinc-induced U937/PR9 cells expressed PML/RARα fusion protein, and resultant increases in ANXA2 transcripts and translational expressions of both ANXA2 and S100A10, while S100A10 transcripts remained constitutive. The transactivation of ANXA2 promoter by PML/RARα fusion protein was 3.29±0.13 fold higher than that by control pSG5 vector or wild-type RARα. The overexpression of ANXA2 in U937 transfected with full-length ANXA2 cDNA was associated with increased S100A10 subunit, although S100A10 transcripts remained constitutive. The tPA-dependent initial rate of plasmin generation (IRPG) in zinc-treated U937/PR9 increased by 2.13-fold, and cell invasiveness increased by 27.6%. Antibodies against ANXA2, S100A10, or combination of both all remarkably inhibited the IRPG and invasiveness in U937/PR9 and NB4. Treatment of zinc-induced U937/PR9 or circulating APL blasts with all-trans retinoic acid (ATRA) significantly reduced cell surface ANXA2 and S100A10 and associated reductions in IRPG and invasiveness. Thus, PML/RARα fusion protein transactivated the ANXA2 promoter to upregulate ANXA2 and accumulate S100A10. Increased AIIt promoted IRPG and invasiveness, both of which were partly abolished by antibodies against ANXA2 and S100A10 or by ATRA.

关键词: annexin A2-S100A10 heterotetramer     PML/RARα fusion protein     plasmin     cell invasion     acute promyelocytic leukemia    

齿轮测量技术100年——回顾与展望

石照耀,费业泰,谢华锟

《中国工程科学》 2003年 第5卷 第9期   页码 13-17

摘要:

全面概述了过去100年齿轮测量技术的发展历程,给出了6件标志性事情;着重论述了测量原理的演变、实现测量原理技术方式的发展以及测量结果的表述与利用;介绍了当今CNC齿轮测量中心的原理、组成和特点;结合

关键词: 齿轮     齿轮测量     齿轮误差     齿轮测量仪器    

Two-dimensional SnS2 nanosheets on Prussian blue template for high performance sodium ion batteries

Sim, Kakui Ma, Zhixiang Huang, Shaozhuan Huang, Ye Wang, Huiying Yang

《化学科学与工程前沿(英文)》 2019年 第13卷 第3期   页码 493-500 doi: 10.1007/s11705-019-1826-z

摘要: Three-dimensional Prussian blue (PB) nanostructures was obtained via a one-step hydrothermal method. Subsequently, two-dimensional tin disulfide (SnS ) nanosheets were grown onto PB through a facile hydrothermal synthesis. The as prepared SnS /PB is further employed as the anode of sodium ion batteries (SIBs). SnS /PB nanoarchitecture delivers a specific capacity of 725.7 mAh∙g at 50 mA∙g . When put through more than 200 cycles, it achieved a stable cycling capacity of 400 mAh∙g at 200 mA∙g . The stable Na storage properties of SnS /PB was attributed to the synergistic effect among the conductive PB carbon, used as the template in this work. These results obtained potentially paves the way for the development of excellent electrochemical performance with stable performance of SIBs.

关键词: Prussian blue     carbon nanocubes     tin disulfide     sodium ion batteries    

HRT波方法准确预测强震时空强的可行性及其汶川8级等强震的震例

赵玉林,钱复业

《中国工程科学》 2009年 第11卷 第6期   页码 111-122

摘要: ,在震前同时测定给出地震三要素(地点、震级和时间)的一种新方法,把孕震过程与前兆产生机理视为“黑箱”,选已知大自然存在的潮汐力波作输入信号;使用专门研发的“PS -100&

关键词: “黑箱”与HRT 波预测模型     “PS -100”HRT 波接收网站     波动前兆的发现及其规律性     HRT 波模型的实用性    

靖边气田陕100井区马五1+2储层水平井开发优化

赵金省,高建英,肖曾利

《中国工程科学》 2013年 第15卷 第10期   页码 66-70

摘要: 结果表明,陕100井区马五1+2储层地质条件适合水平井开发。在对研究区三维精细地质建模的基础上,采用数值模拟对水平井的井网方式、水平段长度、井排距、开发指标等进行了预测。结果表明,最优的井网形式是水平段平行对称布置,采用同时穿越马五12和马五13的阶梯状水平段的水平井,井距和排距均为2 100 m。

关键词: 靖边气田     水平井     开发指标     井网     优化    

Sustainability of metal recovery from E-waste

Biswajit Debnath, Ranjana Chowdhury, Sadhan Kumar Ghosh

《环境科学与工程前沿(英文)》 2018年 第12卷 第6期 doi: 10.1007/s11783-018-1044-9

摘要:

Metal recovery techniques from electronic waste reported in literature.

Metal recovery processes followed in Industries from electronic waste.

Sustainability analysis of metal recovery processes from electronic waste.

关键词: E-waste     Metal recovery     Metal Recovery from E-waste (MREW)     Sustainability    

Lamb wave propagation modeling for structure health monitoring

Xiaoyue ZHANG, Shenfang YUAN, Tong HAO

《机械工程前沿(英文)》 2009年 第4卷 第3期   页码 326-331 doi: 10.1007/s11465-009-0045-6

摘要: This study aims to model the propagation of Lamb waves used in structure health monitoring. A number of different numerical computational techniques have been developed for wave propagation studies. The local interaction simulation approach, used for modeling sharp interfaces and discontinuities in complex media (LISA/SIM theory), has been effectively applied to numerical simulations of elastic wave interaction. This modeling is based on the local interaction simulation approach theory and is finally accomplished through the finite elements software Ansys11. In this paper, the Lamb waves propagating characteristics and the LISA/SIM theory are introduced. The finite difference equations describing wave propagation used in the LISA/SIM theory are obtained. Then, an anisotropic metallic plate model is modeled and a simulating Lamb waves signal is loaded on. Finally, the Lamb waves propagation modeling is implemented.

关键词: Lamb wave     modeling     LISA/SIM theory     finite difference equation     finite element    

risks of heavy metals, polybrominated diphenyl ethers, and polychlorinated dibenzo-dioxins/furans at e-waste

《环境科学与工程前沿(英文)》 2023年 第17卷 第7期 doi: 10.1007/s11783-023-1679-z

摘要:

● Heavy metals and organic toxins may persist in legacy sites for a long time.

关键词: E-waste     Human health risk     Organ risk     Heavy metal toxicity     PBDE     PCDD/F    

标题 作者 时间 类型 操作

基于S3C2410的GPRS数据终端的设计

孙学用

期刊论文

Fabrication of MIL-100(Fe)@SiO

Yinlong Hu,Shuang Zheng,Fumin Zhang

期刊论文

Analysis of 100 consecutive cases of resectable pancreatic neuroendocrine neoplasms: clinicopathological

null

期刊论文

Regulatory mechanism and functional analysis of

null

期刊论文

quality of care for patients with type 2 diabetes in China: findings from the Shanghai Integration Model (SIM

期刊论文

Development of temperature-robust damage factor based on sensor fusion for a wind turbine structure

Jong-Woong PARK,Sung-Han SIM,Jin-Hak YI,Hyung-Jo JUNG

期刊论文

Lignin-based electrospun nanofiber membrane decorated with photo-Fenton Ag@MIF-100(Fe) heterojunctions

期刊论文

Annexin A2-S100A10 heterotetramer is upregulated by PML/RARα fusion protein and promotes plasminogen-dependent

null

期刊论文

齿轮测量技术100年——回顾与展望

石照耀,费业泰,谢华锟

期刊论文

Two-dimensional SnS2 nanosheets on Prussian blue template for high performance sodium ion batteries

Sim, Kakui Ma, Zhixiang Huang, Shaozhuan Huang, Ye Wang, Huiying Yang

期刊论文

HRT波方法准确预测强震时空强的可行性及其汶川8级等强震的震例

赵玉林,钱复业

期刊论文

靖边气田陕100井区马五1+2储层水平井开发优化

赵金省,高建英,肖曾利

期刊论文

Sustainability of metal recovery from E-waste

Biswajit Debnath, Ranjana Chowdhury, Sadhan Kumar Ghosh

期刊论文

Lamb wave propagation modeling for structure health monitoring

Xiaoyue ZHANG, Shenfang YUAN, Tong HAO

期刊论文

risks of heavy metals, polybrominated diphenyl ethers, and polychlorinated dibenzo-dioxins/furans at e-waste

期刊论文