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Crk-associated substrate, vascular smooth muscle and hypertension
TANG Dale
《医学前沿(英文)》 2008年 第2卷 第4期 页码 323-331 doi: 10.1007/s11684-008-0062-6
关键词: Contraction stimulation phosphatase-proline molecular structure discovered hypertension
Protein phosphatase 2A, a key player in Alzheimer’s disease
Rong LIU, Qing TIAN
《医学前沿(英文)》 2009年 第3卷 第1期 页码 8-12 doi: 10.1007/s11684-009-0017-6
关键词: protein phosphatase 2A Alzheimer’s disease holoenzyme composition protein phosphatase 2A inhibitors Leu309 demethylation Tyr307 phosphorylation
Proline-2′-deoxymugineic acid, a phytosiderophore analog, drives beneficial rhizobacterial community
《农业科学与工程前沿(英文)》 doi: 10.15302/J-FASE-2023531
● Proline-2′-deoxymugineic (PDMA) significantly altered the bacterial community in the peanut rhizosphere.
关键词: Beneficial rhizobacteria recruitment peanut plant-soil micronutrition enhancement proline-2′-deoxymugineic acid stable microbial network
Measurement of bone alkaline phosphatase and relative study with osteosarcoma
YANG Zhiping, LI Jianmin, LI Xin, HUO Yanqing, SUN Guangzhi
《医学前沿(英文)》 2007年 第1卷 第1期 页码 54-57 doi: 10.1007/s11684-007-0011-9
LIU Rong, ZENG Ji, ZHOU Xinwen, WANG Jianzhi, PEI Jinjing
《医学前沿(英文)》 2008年 第2卷 第3期 页码 235-238 doi: 10.1007/s11684-008-0044-8
关键词: hyperphosphorylation PP2A activity cellular regulation siRNA siRNA transfection
Expression and clinical implication of PRL-1 and PRL-3 in transitional cell carcinoma of bladder
Bin HAO, Changwei LIU, Huixiang LI
《医学前沿(英文)》 2009年 第3卷 第2期 页码 197-203 doi: 10.1007/s11684-009-0036-3
关键词: transitional cell carcinoma of bladder phosphatase of regenerating liver 1 phosphatase of regenerating liver 3 reverse transcription polymerase chain reaction immunohistochemistry
null
《医学前沿(英文)》 2016年 第10卷 第1期 页码 52-60 doi: 10.1007/s11684-016-0433-3
Hepatocellular carcinoma (HCC) is a lethal liver malignancy worldwide. In this study, we reported that protein phosphatase magnesium-dependent 1δ (PPM1D) was highly expressed in the majority of HCC cases (approximately 59%) and significantly associated with high serum α-fetoprotein (AFP) level (P= 0.044). Kaplan-Meier and Cox regression data indicated that PPM1D overexpression was an independent predictor of HCC-specific overall survival (HR, 2.799; 95% CI, 1.346–5.818, P = 0.006). Overexpressing PPM1D promoted cell viability and invasion, whereas RNA interference-mediated knockdown of PPM1D inhibited proliferation, invasion, and migration of cultured HCC cells. In addition, PPM1D suppression by small interfering RNA decreased the tumorigenicity of HCC cells in vivo. Overall, results suggest that PPM1D is a potential prognostic marker and therapeutic target for HCC.
关键词: PPM1D hepatocellular carcinoma prognosis target therapy
Jie Zhou, Xuewen Du, Jiaqing Wang, Natsuko Yamagata, Bing Xu
《化学科学与工程前沿(英文)》 2017年 第11卷 第4期 页码 509-515 doi: 10.1007/s11705-017-1613-7
关键词: enzyme-instructed self-assembly phosphoserine phosphatase supramolecular hydrogel
Keratin 5-Cre-driven deletion of
Jun Yang, Lianqing Wang, Yingzhi Huang, Keqiang Liu, Chaoxia Lu, Nuo Si, Rongrong Wang, Yaping Liu, Xue Zhang
《医学前沿(英文)》 2020年 第14卷 第3期 页码 305-317 doi: 10.1007/s11684-019-0722-8
关键词: acne inversa mouse model interleukin 1 family member 6 small proline rich protein 2D key inflammatory cytokine
标题 作者 时间 类型 操作
Proline-2′-deoxymugineic acid, a phytosiderophore analog, drives beneficial rhizobacterial community
期刊论文
Measurement of bone alkaline phosphatase and relative study with osteosarcoma
YANG Zhiping, LI Jianmin, LI Xin, HUO Yanqing, SUN Guangzhi
期刊论文
Effect of inhibiting tyrosine kinase Src expression on protein phosphatase 2A and tau phosphorylation
LIU Rong, ZENG Ji, ZHOU Xinwen, WANG Jianzhi, PEI Jinjing
期刊论文
Expression and clinical implication of PRL-1 and PRL-3 in transitional cell carcinoma of bladder
Bin HAO, Changwei LIU, Huixiang LI
期刊论文
Protein phosphatase magnesium-dependent 1δ is a novel tumor marker and target in hepatocellular carcinoma
null
期刊论文
Enzyme-instructed self-assembly of peptides containing phosphoserine to form supramolecular hydrogels as potential soft biomaterials
Jie Zhou, Xuewen Du, Jiaqing Wang, Natsuko Yamagata, Bing Xu
期刊论文