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Serologic study on the outbreak of acute upper respiratory tract infections caused by adenovirus 3

JIANG Lufang, JU Liwen, LIN Yuzun, ZHOU Liandi, YU Shunzhang, JIANG Qingwu, JIANG Renjie

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 215-218 doi: 10.1007/s11684-007-0041-3

Abstract: Twenty throat swabs were collected with 13 of them presenting an adenovirus (Ad)-like cytopathogenicMoreover, they were identified as adenovirus type 3 (Ad3) by type-specific PCR and sequencing of thestudy, we can definitively diagnose that this outbreak of acute respiratory infections was caused by Adenovirus

Keywords： Twenty     Adenovirus     cytopathogenic     type-specific     AURTI    

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Investigation of gene therapy of denovirus in immune suppression

XIA Xi, WANG Beibei, CAO Li, CHEN Gang, WU Peng, LU Yunping, ZHOU Jianfeng, MA Ding

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 386-390 doi: 10.1007/s11684-008-0074-2

Abstract: The aim of this paper is to investigate the safety of reconstructed adenovirus in immunosuppressive therapeuticsImmunohistochemistry was used to examine the expression of adenovirus in organs.as time went by in the control group, while it did not happen in the experimental group in which the adenovirusshowed a relative increase compared with their counterparts ( < 0.05). (3) The distributions of adenovirusReconstructed adenovirus as a vector is definitely safe in immunosuppressive therapeutics, and ciclosporin

Keywords： different     reversible inflammation     immunohistochemistry     reconstructed adenovirus     ciclosporin    

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Adenovirus-mediated antisense ERK2 gene therapy ameliorates chronic allograft nephropathy in a rat model

Zhao DING, Zhishui CHEN, Xilin CHEN, Ming CAI, Hui GUO, Nianqiao GONG

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 204-210 doi: 10.1007/s11684-009-0039-0

Abstract: To investigate the effect and underlying mechanism of adenovirus-mediated antisense ERK2 (Adanti-ERK2

Keywords： anti-ERK2     renal transplantation     epithelial mesenchymal transition     chronic allograft nephropathy    

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Expression and function of DMT1 without IRE in C6 cells mediated by recombinant adenovirus

Xixun DU*, Huamin XU*, Hong JIANG, Jun WANG, Lei WANG, Junxia XIE

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 67-71 doi: 10.1007/s11684-009-0010-0

Abstract: In the present study, we constructed a recombinant adenovirus containing the gene of DMT1 without theconfirmed pAdEasy1-DMT1-IRE contained gene DMT1-IRE, indicating the successful construction of recombinant adenovirusGFP fluorescence further confirmed the generation of adenovirus.

Keywords： divalent metal transporter 1     recombinant adenovirus     homologous recombination     iron    

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Adenovirus-mediated tissue inhibitor of metalloproteinase-3 gene transfection inhibits rabbit intervertebral

Xudong YU MM, Zengwu SHAO MD, Liming XIONG MD, Weiwei XU MM, Hezhong WANG MM, Huifa XU MM,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 415-420 doi: 10.1007/s11684-009-0072-z

Abstract: The aim of this study was to investigate the inhibitory effects of recombinant adenovirus vector carryingdiscs as follows: 20μL of normal saline in group 1; 20μL of RAd66 (an empty adenovirus

Keywords： tissue inhibitor of metalloproteinase-3     intervertebral disc     rabbit     gene therapy    

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Lung-Targeted Transgene Expression of Nanocomplexed Ad5 Enhances Immune Response in the Presence of Preexisting Immunity Article

Yilong Yang, Shipo Wu, Yudong Wang, Fangze Shao, Peng Lv, Ruihua Li, Xiaofan Zhao, Jun Zhang, Xiaopeng Zhang, Jianmin Li, Lihua Hou, Junjie Xu, Wei Chen

Engineering 2023, Volume 27, Issue 8,   Pages 127-139 doi: 10.1016/j.eng.2022.12.007

Abstract:

Recombinant adenovirus serotype 5 (Ad5) vector has been widely applied in vaccine development targetingforming a complex with Ad5, significantly increase the transgene expression of Ad5 in both coxsackievirus-adenovirus

Keywords： Adenovirus serotype 5     Vaccine     Preexisting immunity     Nanoparticles     Transgene expression    

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Title Author Date Type Operation

Serologic study on the outbreak of acute upper respiratory tract infections caused by adenovirus 3

JIANG Lufang, JU Liwen, LIN Yuzun, ZHOU Liandi, YU Shunzhang, JIANG Qingwu, JIANG Renjie

Journal Article

Investigation of gene therapy of denovirus in immune suppression

XIA Xi, WANG Beibei, CAO Li, CHEN Gang, WU Peng, LU Yunping, ZHOU Jianfeng, MA Ding

Journal Article

Adenovirus-mediated antisense ERK2 gene therapy ameliorates chronic allograft nephropathy in a rat model

Zhao DING, Zhishui CHEN, Xilin CHEN, Ming CAI, Hui GUO, Nianqiao GONG

Journal Article

Expression and function of DMT1 without IRE in C6 cells mediated by recombinant adenovirus

Xixun DU*, Huamin XU*, Hong JIANG, Jun WANG, Lei WANG, Junxia XIE

Journal Article

Adenovirus-mediated tissue inhibitor of metalloproteinase-3 gene transfection inhibits rabbit intervertebral

Xudong YU MM, Zengwu SHAO MD, Liming XIONG MD, Weiwei XU MM, Hezhong WANG MM, Huifa XU MM,

Journal Article

Lung-Targeted Transgene Expression of Nanocomplexed Ad5 Enhances Immune Response in the Presence of Preexisting Immunity

Yilong Yang, Shipo Wu, Yudong Wang, Fangze Shao, Peng Lv, Ruihua Li, Xiaofan Zhao, Jun Zhang, Xiaopeng Zhang, Jianmin Li, Lihua Hou, Junjie Xu, Wei Chen

Journal Article