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2016 1

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DCEF 1

SDF-1/CXCR-4 1

migration 1

osteogenesis differentiation 1

rBMSCs 1

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Influence of the intensity and loading time of direct current electric field on the directional migration of rat bone marrow mesenchymal stem cells

Xiaoyu Wang,Yuxuan Gao,Haigang Shi,Na Liu,Wei Zhang,Hongbo Li

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 286-296 doi: 10.1007/s11684-016-0456-9

Abstract: : (1) the direction of rat BMSC (rBMSC) migration upon exposure to a direct current electric field (DCEFin rBMSC migration as induced by DCEF.Results showed that rBMSCs migrated to the positive electrode of the DCEF, and that the DCEF of 200 mVMoreover, when CXCR4 was inhibited, rBMSC migration due to DCEF was partially blocked.These findings indicated that DCEF can effectively induce rBMSC migration.

Keywords： DCEF     migration     osteogenesis differentiation     rBMSCs     SDF-1/CXCR-4    

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Influence of the intensity and loading time of direct current electric field on the directional migration of rat bone marrow mesenchymal stem cells

Xiaoyu Wang,Yuxuan Gao,Haigang Shi,Na Liu,Wei Zhang,Hongbo Li

Journal Article