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Th17 Cells in autoimmune diseases

Lei Han,Jing Yang,Xiuwen Wang,Dan Li,Ling Lv,Bin Li

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 10-19 doi: 10.1007/s11684-015-0388-9

Abstract:

Th17 cells are a new subset of CD4+ T cells involved in the clearance of extracellularAccumulating evidence suggests that Th17 cells and their signature cytokines have a pivotal role in theHere, we summarize recent research progress on Th17 function in the development and pathogenesis of autoimmuneWe also propose to identify new small molecule compounds to manipulate Th17 function for potential therapeutic

Keywords： IL-17     Th17 cells     RORγt     autoimmune diseases     posttranslational modification     inhibitors    

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Relationship between Th17 cells and allograft rejection

Zhikun ZHENG MM, Jinsong LI MD, Ke JIANG MD,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 491-494 doi: 10.1007/s11684-009-0066-x

Abstract: Thl7 cells, a special kind of auxiliary type T cells, can secrete IL-17A, IL-17F, IL-21, IL-22, etc.,As a different subset from the Thl and Th2 cells, Th17 cells play an important role in the developmentIL-23 can promote the production of IL17, as well as participate in amplification and maintenance ofthe survival of IL-l7 generating cells.As our knowledge on Th17 family members is rapidly growing and changing, it will be important to specify

Keywords： TH17 cells     regulation     allograft     rejection    

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sources of dissolved organic matter from wastewater treatment plants and their mediation effect on 17α-ethinylestradiol

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 6, doi: 10.1007/s11783-023-1669-1

Abstract:

● EE2 photodegradation behavior in the presence of four WWTPs’ DOM was explored.

Keywords： Photosensitivity sources     17α-ethinylestradiol     Photodegradation     Dissolved organic matter     Wastewater    

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Predictive values of plasma TNFα and IL-8 for intracranial hemorrhage in patients with acute promyelocytic

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 909-918 doi: 10.1007/s11684-021-0890-1

Abstract: Results showed that tumor necrosis factor α and interleukin 8 (IL-8) were vital in distinguishing patientsFinally, in-vitro and in-vivo experimental evidence were provided to show that IL-8 influenced

Keywords： acute promyelocytic leukemia     intracranial hemorrhage     cytokines     biomarker    

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Effect of IL-10 on formation of foam cell induced by ox-LDL

WANG Fei, DAI Yalei, XU Ting, XU Bo, WANG Kaifeng

Frontiers of Medicine 2008, Volume 2, Issue 3,   Pages 298-302 doi: 10.1007/s11684-008-0057-3

Abstract: In this study the effects of lipopolysaccharide (LPS) and interleukin-10 (IL-10) on the formation ofThe cells were further stimulated by ox-LDL, ox-LDL plus LPS, ox-LDL plus IL-10 and LPS.However, the significant elevation by LPS was abrogated when IL-10 was added.IL-10, an anti-inflammatory cytokine, can inhibit the effect of ox-LDL and LPS.The inhibitive effect of IL-10 is an important factor for delaying atherosclerosis processes.

Keywords： inflammatory     presence     interleukin-10     dose-dependent     ox-LDL    

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Traces and echoes of De Architectura by Marcus Vitruvius Pollio in the work of Xu Guangqi in 17th

Michela CIGOLA,Yibing FANG

Frontiers of Mechanical Engineering 2016, Volume 11, Issue 1,   Pages 3-11 doi: 10.1007/s11465-015-0359-5

Abstract: Dynasty, in the development of European scientific and technical knowledge in China between the 16th and 17th

Keywords： Vitruvius’ De Architectura     Xu Guangqi’s Taixi Shuifa     Jesuit missionaries     Italian Renaissance     drawing     representation    

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Emergence in cyber-physical systems: potential and risk

Shmuel Tyszberowicz, David Faitelson,tyshbe@tau.ac.il,davidf@afeka.ac.il

Frontiers of Information Technology & Electronic Engineering 2020, Volume 21, Issue 11,   Pages 1535-1670 doi: 10.1631/FITEE.2000279

Abstract: (CPSs) are distributed assemblages of computing, communicating, and physical components that sense their environment, algorithmically assess the incoming information, and affect their physical environment. Thus, they share a common structure with other , and therefore share both the possible benefits and the probable harmful effects of emergent phenomena. Emergence is an often unexpected pattern that arises from the interactions among the individual system components and the environment. In this paper we focus on three major problems concerning emergence in the context of CPSs: how to successfully exploit emergence, how to avoid its detrimental effects in a single CPS, and how to avoid harmful emergence that arises due to unexpected interaction among several independently developed CPSs that are operating in the same environment. We review the state of the research with regard to these problems and outline several approaches that could be used to address them.
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Removal of 17β-estradiol in laccase catalyzed treatment processes

XIA Qing,KONG Deyang,LIU Guoqiang,HUANG Qingguo,ALALEWI Aamr,LU Junhe

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 3,   Pages 372-378 doi: 10.1007/s11783-013-0567-3

Abstract: The removal of 17β-estradiol (E2) in laccase catalyzed oxidative coupling processes was systematically

Keywords： 17β-estradiol     laccase     oxidative coupling processes     kinetics     mechanisms    

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Decomposition of aqueous chlorinated contaminants by UV irradiation with H

Eunsung KAN,Chang-Il KOH,Kyunghyuk LEE,Joonwun KANG

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 3,   Pages 429-435 doi: 10.1007/s11783-014-0677-6

Abstract: In the present study, the decomposition rates of carbon tetrachloride (CCl ) and 2,4-dichlorophenol (2,4-DCP) in water by the ultraviolet (UV) light irradiation alone and H O /UV were experimentally investigated. The detailed experimental studies have been conducted for examining treatment capacities of the two different ultraviolet light sources (low and medium pressure Hg arc) in H O /UV processes. The low or medium UV lamp alone resulted in a 60%–90% decomposition of 2,4-DCP while a slight addition of H O resulted in a drastic enhancement of the 2,4-DCP decomposition rate. The decomposition rate of 2,4-DCP with the medium pressure UV lamp alone was about 3–6 times greater than the low pressure UV lamp alone. In the direct photolysis of aqueous CCl , the medium pressure UV lamp had advantage over the low pressure UV lamp because the molar extinction coefficient of CCl at shorter wavelength (210–220 nm) is about 20 to 50 times higher than that at 254 nm. However, adding H O to the medium pressure UV lamp system rendered a negative oxidation rate because H O acted as a UV absorber being competitive with CCl due to negligible reaction between CCl and OH radicals. The results from the present study indicated significant influence of the photochemical properties of the target contaminants on the photochemical treatment characteristics for designing cost-effective UV-based degradation of toxic contaminants.

Keywords： H2O2/ultraviolet (UV) light     advanced oxidation     UV light irradiation     chlorinated contaminants     photochemical treatment characteristics    

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Active steering control strategy for articulated vehicles Project supported by the Program for Changjiang Scholars and Innovative Research Team in University, China (No. IRT0626) Article

Kyong-il KIM,Hsin GUAN,Bo WANG,Rui GUO,Fan LIANG

Frontiers of Information Technology & Electronic Engineering 2016, Volume 17, Issue 6,   Pages 576-586 doi: 10.1631/FITEE.1500211

Abstract: To improve maneuverability and stability of articulated vehicles, we design an active steering controller, including tractor and trailer controllers, based on linear quadratic regulator (LQR) theory. First, a three-degree-of-freedom (3-DOF) model of the tractor-trailer with steered trailer axles is built. The simulated annealing particle swarm optimization (SAPSO) algorithm is applied to identify the key parameters of the model under specified vehicle speed and steering wheel angle. Thus, the key parameters of the simplified model can be obtained according to the vehicle conditions using an online look-up table and interpolation. Simulation results show that vehicle parameter outputs of the simplified model and TruckSim agree well, thus providing the ideal reference yaw rate for the controller. Then the active steering controller of the tractor and trailer based on LQR is designed to follow the desired yaw rate and minimize their side-slip angle of the center of gravity (CG) at the same time. Finally, simulation tests at both low speed and high speed are conducted based on the TruckSim-Simulink program. The results show significant effects on the active steering controller on improving maneuverability at low speed and lateral stability at high speed for the articulated vehicle. The control strategy is applicable for steering not only along gentle curves but also along sharp curves.

Keywords： Articulated vehicle     Sharp curve     Lateral stability     Linear quadratic regulator (LQR)    

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Cytokine storm and translating IL-6 biology into effective treatments for COVID-19

Frontiers of Medicine doi: 10.1007/s11684-023-1044-4

Abstract: Considering that high levels of interleukin-6 (IL-6) have been detected in several highly pathogenicacute respiratory syndrome in 2002, the Middle East respiratory syndrome in 2012, and COVID-19, the ILThus, we review the history of cytokine storm and the process of targeting IL-6 signaling to elucidate

Keywords： SARS-CoV-2     COVID-19     cytokine storm     interleukin-6     tocilizumab    

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Effects of heavy rainfall on the composition of airborne bacterial communities

Gwang Il Jang, Chung Yeon Hwang, Byung Cheol Cho

Frontiers of Environmental Science & Engineering 2018, Volume 12, Issue 2, doi: 10.1007/s11783-018-1008-0

Abstract: Wet deposition scavenges particles and particle-associated bacteria from the air column, but the impact of raindrops on various surfaces on Earth causes emission of surface-associated bacteria into the air column. Thus, after rainfall, these two mechanisms are expected to cause changes in airborne bacterial community composition (BCC). In this study, aerosol samples were collected at a suburban site in Seoul, Korea before and after three heavy rainfall events in April, May, and July 2011. BCC was investigated by pyrosequencing the 16S rRNA gene in aerosol samples. Interestingly, the relative abundance of non-spore forming operational taxonomic units (OTUs) was always higher in post-rain aerosol samples. In particular, the absolute and relative abundances of airborne always increased after rainfall, whereas those of airborne , including and , consistently decreased. Marine bacterial sequences, which were temporally important in aerosol samples, also decreased after rainfall events. Further, increases in pathogen-like sequences were often observed in post-rain air samples. Rainfall events seemed to affect airborne BCCs by the combined action of the two mechanisms, with potentially adverse effects on human and plant health.

Keywords： Aerosol     Bacteria     Community composition     Pyrosequencing     Rain    

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Successful production of an all-female common carp (Cyprinus carpio L.) population using cyp17a1 Article

Gang Zhai,Tingting Shu,Kuangxin Chen,Qiyong Lou,Jingyi Jia,Jianfei Huang,Chuang Shi,Xia Jin,Jiangyan He,Donghuo Jiang,Xueqiao Qian,Wei Hu,Zhan Yin,

Engineering 2022, Volume 8, Issue 1,   Pages 181-189 doi: 10.1016/j.eng.2021.03.026

Abstract: Male and female heterozygous cyp17a1-deficient common carp were first obtained using the clusteredAn all-male phenotype for homozygous cyp17a1-deficient carp, regardless of the individuals&rsquoour laboratory was used to screen the neomale carp population with the XX genotype from the cyp17a1The neomale common carp were then mated with wild-type (WT) females (cyp17a1+/+ XX genotype)The average body weight of cyp17a1+/− XX females was higher by 6.60% (8 mpf) and 32.66%

Keywords： Common carp     Sexual dimorphism     Growth     cyp17a1     Sex steroids     All-female population    

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Adsorption properties of polycarboxylate ether-based superplasticizer on cement particles and their resultant dispersion

Jinyoung YOON; Byoung Il CHOI; Jae Hong KIM

Frontiers of Structural and Civil Engineering 2022, Volume 16, Issue 4,   Pages 506-514 doi: 10.1007/s11709-022-0813-5

Abstract: The cement dispersion performance of a polycarboxylate (PCE)-based superplasticizer is highly related to their adsorption behaviors as a function of time. This study evaluated effects of PCEs on rheological properties of cementitious materials. First, characteristics of PCEs were characterized via permeation chromatography (GPC) and Fourier-transform infrared spectrometry (FT-IR). The adsorption behavior of single and blended PCEs on cementitious composites was identified using total organic carbon analyzer (TOC). Based on the measurement of PCE adsorption, the changes of rheological properties of cementitious materials as well as the number of dispersed cement particles were characterized using a rheometer and laser spectroscopy, respectively. The experimental results support the systematic mechanism of PCE adsorption, cement dispersion, and the decrease in viscosity of cementitious materials.

Keywords： adsorption     polycarboxylate     superplasticizer     rheology     dispersion    

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A 17–26.5 GHz 42.5 dBm broadband and highly efficient gallium nitride power amplifier design Correspondences

Ming LI, Zhiqun LI, Quan ZHENG, Lanfeng LIN, Hongqi TAO,liming_2018@seu.edu.cn,zhiqunli@seu.edu.cn

Frontiers of Information Technology & Electronic Engineering 2022, Volume 23, Issue 2,   Pages 346-350 doi: 10.1631/FITEE.2000513

Abstract: A wideband power amplifier is one of the key components in mobile communication systems and radar systems because it is a key component of radio frequency (RF) front-end systems, and its performance occupies a dominant position in the entire system function. GaN as the representative of the third generation of wide band gap semiconductors has the advantages of wide band gap, high electron mobility, and high breakdown field strength (Mishra et al., 2008; Millán et al., 2014). The power density of the device far exceeds that of Si and GaAs. Because of its high frequency, high power, high efficiency, high temperature resistance, high radiation resistance, and other excellent characteristics, GaN MMICs have broad application prospects in the microwave and millimeter wave bands.

Keywords： K波段；高效率；宽带；氮化镓（GaN）；功率放大器    

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Title Author Date Type Operation

Th17 Cells in autoimmune diseases

Lei Han,Jing Yang,Xiuwen Wang,Dan Li,Ling Lv,Bin Li

Journal Article

Relationship between Th17 cells and allograft rejection

Zhikun ZHENG MM, Jinsong LI MD, Ke JIANG MD,

Journal Article

sources of dissolved organic matter from wastewater treatment plants and their mediation effect on 17α-ethinylestradiol

Journal Article

Predictive values of plasma TNFα and IL-8 for intracranial hemorrhage in patients with acute promyelocytic

Journal Article

Effect of IL-10 on formation of foam cell induced by ox-LDL

WANG Fei, DAI Yalei, XU Ting, XU Bo, WANG Kaifeng

Journal Article

Traces and echoes of De Architectura by Marcus Vitruvius Pollio in the work of Xu Guangqi in 17th

Michela CIGOLA,Yibing FANG

Journal Article

Emergence in cyber-physical systems: potential and risk

Shmuel Tyszberowicz, David Faitelson,tyshbe@tau.ac.il,davidf@afeka.ac.il

Journal Article

Removal of 17β-estradiol in laccase catalyzed treatment processes

XIA Qing,KONG Deyang,LIU Guoqiang,HUANG Qingguo,ALALEWI Aamr,LU Junhe

Journal Article

Decomposition of aqueous chlorinated contaminants by UV irradiation with H

Eunsung KAN,Chang-Il KOH,Kyunghyuk LEE,Joonwun KANG

Journal Article

Active steering control strategy for articulated vehicles Project supported by the Program for Changjiang Scholars and Innovative Research Team in University, China (No. IRT0626)

Kyong-il KIM,Hsin GUAN,Bo WANG,Rui GUO,Fan LIANG

Journal Article

Cytokine storm and translating IL-6 biology into effective treatments for COVID-19

Journal Article

Effects of heavy rainfall on the composition of airborne bacterial communities

Gwang Il Jang, Chung Yeon Hwang, Byung Cheol Cho

Journal Article

Successful production of an all-female common carp (Cyprinus carpio L.) population using cyp17a1

Gang Zhai,Tingting Shu,Kuangxin Chen,Qiyong Lou,Jingyi Jia,Jianfei Huang,Chuang Shi,Xia Jin,Jiangyan He,Donghuo Jiang,Xueqiao Qian,Wei Hu,Zhan Yin,

Journal Article

Adsorption properties of polycarboxylate ether-based superplasticizer on cement particles and their resultant dispersion

Jinyoung YOON; Byoung Il CHOI; Jae Hong KIM

Journal Article

A 17–26.5 GHz 42.5 dBm broadband and highly efficient gallium nitride power amplifier design

Ming LI, Zhiqun LI, Quan ZHENG, Lanfeng LIN, Hongqi TAO,liming_2018@seu.edu.cn,zhiqunli@seu.edu.cn

Journal Article