Resource Type

Journal Article 7

Year

2023 2

2021 1

2020 1

2019 1

2018 2

Keywords

ROS 4

Lymnea luteola 1

Pseudomonas stutzeri 1

Acute toxicity 1

Aerobic denitrification 1

DNA damage 1

Denitrification 1

Dissolved organic matter 1

Ecotoxicity 1

Humic substance 1

IVF-ET 1

Microbiology 1

Microplastics 1

NADPH oxidase 1

PCOS 1

Persist organic pollutants 1

Persistent free radicals (PFRs) 1

Photoaging 1

Polycyclic aromatic hydrocarbons (PAHs) 1

Profenofos 1

open ︾

Search scope:

排序： Display mode:

Discovery of novel ursolic acid derivatives as effective antimicrobial agents through a ROS-mediated

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 12,   Pages 2101-2113 doi: 10.1007/s11705-023-2361-5

Abstract: In response to the reduction of food production and economic losses caused by plant bacterial diseases, it is necessary to develop new, efficient, and green pesticides. Natural products are rich and sustainable source for the development of new pesticides due to their low toxicity, easy degradation, and eco-friendliness. In this study, we prepared three series of ursolic acid derivatives and assessed their antibacterial ability. Most target compounds exhibited outstanding antibacterial activities. Among them, the relative optimal EC50 values of Xanthomonas oryzae pv. oryzae and Xanthomonas axonopodis pv. citri were 2.23 (A17) and 1.39 (A16) μg·mL–1, respectively. The antimicrobial mechanism showed that compound A17 induced an excessive accumulation and production of reactive oxygen species in bacteria and damaged the cell membrane integrity to kill bacteria. More interestingly, the addition of low concentrations of exogenous hydrogen peroxide enhanced the antibacterial efficacy of compound A17 against Xanthomonas oryzae pv. oryzae. These entertaining results suggested that compound A17 induced an apparent apoptotic behavior in the tested bacteria. Overall, we developed the promising antimicrobial agents that destroyed the redox system of phytopathogenic bacteria, further demonstrating the unprecedented potential of ursolic acid for agricultural applications.

Keywords： ursolic acid     antibacterial activities     reactive oxygen species     apoptosis    

HTML PDF Collect

Photoaging mechanism of microplastics: a perspective on the effect of dissolved organic matter in natural water

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 11, doi: 10.1007/s11783-023-1743-8

Abstract:

● Microplastics (MPs) undergo photoaging in natural water under light irradiation.

Keywords： Microplastics     Photoaging     Dissolved organic matter     ROS generation    

HTML PDF Collect

Toxic effect of sodium perfluorononyloxy-benzenesulfonate on in aerobic denitrification, cell structure and gene expression

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 5, doi: 10.1007/s11783-021-1391-9

Abstract:

• OBS inhibited the growth of P. stutzeri and destroyed its structure.

Keywords： perfluorononyloxy-benzenesulfonate     Aerobic denitrification     Pseudomonas stutzeri     Ecotoxicity     ROS    

HTML PDF Collect

Detection of oxidative stress and DNA damage in freshwater snail

Daoud Ali, Huma Ali, Saud Alifiri, Saad Alkahtani, Abdullah A Alkahtane, Shaik Althaf Huasain

Frontiers of Environmental Science & Engineering 2018, Volume 12, Issue 5, doi: 10.1007/s11783-018-1039-6

Abstract:

Freshwater snail (Lymnea luteola L.) is good bio indicator of water pollution.

Profenofos is tested for its molluscicidal activity against Lymnea luteola L. snail.

Deleterious effects on some oxidative stress were detected.

Profenofos has a genotoxic effect on Lymnea luteola L. snails.

Keywords： Acute toxicity     Profenofos     ROS     oxidative stress     DNA damage     Lymnea luteola    

HTML PDF Collect

Persistent free radicals in humin under redox conditions and their impact in transforming polycyclic aromatic hydrocarbons

Hanzhong Jia, Yafang Shi, Xiaofeng Nie, Song Zhao, Tiecheng Wang, Virender K. Sharma

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 4, doi: 10.1007/s11783-020-1252-y

Abstract: . • The newly produced PFRs readily release electrons to oxygen and generate ROS. • PFR-induced ROS mediateunstable” free radicals released an electron to O2, inducing the formation of reactive oxygen species (ROSThe generated ROS promoted the degradation of polycyclic aromatic hydrocarbons based on the radical quenching

Keywords： Polycyclic aromatic hydrocarbons (PAHs)     Persistent free radicals (PFRs)     Redox     Reactive oxygen species (ROS    

HTML PDF Collect

Important parameters in plasma jets for the production of RONS in liquids for plasma medicine: A brief review

Anna Khlyustova, Cédric Labay, Zdenko Machala, Maria-Pau Ginebra, Cristina Canal

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 2,   Pages 238-252 doi: 10.1007/s11705-019-1801-8

Abstract: Reactive oxygen and nitrogen species (RONS) are among the key factors in plasma medicine. They are generated by atmospheric plasmas in biological fluids, living tissues and in a variety of liquids. This ability of plasmas to create a delicate mix of RONS in liquids has been used to design remote or indirect treatments for oncological therapy by treating biological fluids by plasmas and putting them in contact with the tumour. Documented effects include selective cancer cell toxicity, even though the exact mechanisms involved are still under investigation. However, the “right” dose for suitable therapeutical activity is crucial and still under debate. The wide variety of plasma sources hampers comparisons. This review focuses on atmospheric pressure plasma jets as the most studied plasma devices in plasma medicine and compiles the conditions employed to generate RONS in relevant liquids and the concentration ranges obtained. The concentrations of H O , NO , NO and short-lived oxygen species are compared critically to provide a useful overview for the reader.

Keywords： atmospheric plasma jets     liquids     ROS     RNS     plasma-dose    

HTML PDF Collect

Oxidative stress in granulosa cells contributes to poor oocyte quality and IVF-ET outcomes in women with polycystic ovary syndrome

Qiaohong Lai, Wenpei Xiang, Qing Li, Hanwang Zhang, Yufeng Li, Guijin Zhu, Chengliang Xiong, Lei Jin

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 518-524 doi: 10.1007/s11684-017-0575-y

Abstract:

The increased levels of intracellular reactive oxygen species (ROS) in granulosa cells (GCs) may affectIVF-ET) results of 22 patients with PCOS and 25 patients with tubal factor infertility and detected the ROS(diphenyleneiodonium and apocynin) significantly reduced the ROS production in the PCOS group.In conclusion, the increased ROS expression levels in PCOS GCs greatly induced cell apoptosis, whichNADPH oxidase pathway may be involved in the mechanism of ROS production in GCs of women with PCOS.

Keywords： PCOS     ROS     granulosa cell     IVF-ET     NADPH oxidase    

HTML PDF Collect

Title Author Date Type Operation

Discovery of novel ursolic acid derivatives as effective antimicrobial agents through a ROS-mediated

Journal Article

Photoaging mechanism of microplastics: a perspective on the effect of dissolved organic matter in natural water

Journal Article

Toxic effect of sodium perfluorononyloxy-benzenesulfonate on in aerobic denitrification, cell structure and gene expression

Journal Article

Detection of oxidative stress and DNA damage in freshwater snail

Daoud Ali, Huma Ali, Saud Alifiri, Saad Alkahtani, Abdullah A Alkahtane, Shaik Althaf Huasain

Journal Article

Persistent free radicals in humin under redox conditions and their impact in transforming polycyclic aromatic hydrocarbons

Hanzhong Jia, Yafang Shi, Xiaofeng Nie, Song Zhao, Tiecheng Wang, Virender K. Sharma

Journal Article

Important parameters in plasma jets for the production of RONS in liquids for plasma medicine: A brief review

Anna Khlyustova, Cédric Labay, Zdenko Machala, Maria-Pau Ginebra, Cristina Canal

Journal Article

Oxidative stress in granulosa cells contributes to poor oocyte quality and IVF-ET outcomes in women with polycystic ovary syndrome

Qiaohong Lai, Wenpei Xiang, Qing Li, Hanwang Zhang, Yufeng Li, Guijin Zhu, Chengliang Xiong, Lei Jin

Journal Article