Resource Type

Journal Article 1

Year

2022 1

Keywords

Nrf2 signaling pathway 1

aminoglycosides 1

apigenin 1

ototoxicity 1

oxidative stress 1

Search scope:

排序： Display mode:

Apigenin alleviates neomycin-induced oxidative damage via the Nrf2 signaling pathway in cochlear hair

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 637-650 doi: 10.1007/s11684-021-0864-3

Abstract: We tested the potential effect of apigenin, a natural flavonoid with anticancer, anti-inflammatory, andResults showed that apigenin significantly ameliorated the loss of hair cells and the accumulation ofsuggested that the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway was activated by apigeninDisruption of the Nrf2 axis abolished the effects of apigenin on the alleviation of oxidative stressThis study provided evidence of the protective effect of apigenin on cochlear hair cells and its underlying

Keywords： apigenin     aminoglycosides     ototoxicity     oxidative stress     Nrf2 signaling pathway    

HTML PDF Collect

Title Author Date Type Operation

Apigenin alleviates neomycin-induced oxidative damage via the Nrf2 signaling pathway in cochlear hair

Journal Article